Results 1 to 10 of about 7,825 (61)
Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023 Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang +6 more
wiley +1 more source
Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019 目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua +6 more
wiley +1 more source
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Long‐term use of lokivetmab in dogs with atopic dermatitis
Veterinary Dermatology, Volume 35, Issue 6, Page 683-693, December 2024.Background – Lokivetmab, a caninised monoclonal antibody against interleukin (IL)‐31, is an effective treatment for the pruritus associated with canine atopic dermatitis (cAD). Objectives – To investigate the efficacy and safety of lokivetmab during long‐term treatment defined as at least three consecutive lokivetmab injections in atopic dogs under ...
Bettina Kasper +2 more
wiley +1 more source
Maternal ethnicity and socioeconomic deprivation: influence on adverse pregnancy outcomes
Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 2, Page 187-192, August 2024.ABSTRACT Objective To evaluate the relative importance of ethnicity and socioeconomic deprivation in determining the likelihood and prevalence of placentally derived composite of adverse pregnancy outcomes (CAPO) and composite of severe adverse pregnancy outcomes (CAPO‐S).
M. Minopoli +5 more
wiley +1 more source
Physiological Entomology, Volume 49, Issue 2, Page 67-90, June 2024.Olfactory receptor neurons (ORNs) in insect antennae project axons to glomeruli in the antennal lobe for odor processing by local interneurons. Uniglomerular projection neurons (PNs) relay processed odor information to the mushroom body and lateral horn.
Saleem Jaffar, Guy Smagghe, Yongyue Lu
wiley +1 more source
Integrative Conservation, Volume 3, Issue 1, Page 36-45, March 2024.Threatened and endangered species that occur in coastal areas are susceptible to the impacts of hurricanes that can destroy and reorganize their habitats. We used long‐term tracking of endangered beach mice to reveal they survive these impacts by using high elevation dune habitats to stay safe.
Michael V. Cove +5 more
wiley +1 more source
[Advances in targeted therapies for chronic spontaneous urticaria]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanZhou L, Hu C, Wang S, Zhang R.
europepmc +1 more source
[Liver-bone axis: novel mechanisms and strategies for MAFLD regulation]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWang YW, Yan XZ, You H, Yang AT.
europepmc +1 more source