Interleukin-8 and tumor necrosis factor-α levels in vitreous samples from patients with diabetic retinopathy [PDF]
, 2013 AIM: To measure the interleukin-8(IL-8)and tumor necrosis factor-α(TNF-α)levels in vitreous samples obtained the patients undergoing pars plana vitrectomy(PPV)due to diabetic retinopathy(DR), then to compare these results with those of the control group ...
Alper Sengul +7 more
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Effect of intramuscular adipose tissue in the skeletal muscle of thigh on glucose metabolism in male patients with obesity [PDF]
, 2023 Objective·To investigate the correlation between intramuscular adipose tissue (IMAT) content and glucose metabolism in male patients with obesity.Methods·Eighty male patients with obesity were recruited from the Endocrinology Department of Renji Hospital,
DONG Ying +5 more
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血清炎症细胞因子检测对预警子宫内膜癌术后深静脉血栓的应用分析
Zhongguo shiyan zhenduanxue, 2022 目的 探讨血清炎症细胞因子检测对预警子宫内膜癌术后深静脉血栓（DVT）的应用分析。方法 收集2017年3月到2021年3月收治的56例子宫内膜癌手术后发生DVT患者临床资料，将其纳入DVT组，另选取同期56例术后未发生DVT患者临床资料，将其纳入非DVT组。两组术前均测定血清炎症细胞因子水平[中性粒细胞、抗肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)、白细胞介素-8(IL-8)]，并分析其检测效能。结果DVT组患者血液中性粒细胞计数高于非DVT组 ...
王莉莎 +5 more
doaj
DAPT attenuates ox-LDL-induced human umbilical vein endothelial cell injury [PDF]
, 2017 目的:; 探究gamma-分泌酶抑制剂N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine; t-butyl ester (DAPT)在氧化低密度脂蛋白(oxidized low-density lipoprotein,; ox-LDL)损伤人脐静脉内皮细胞(human umbilical vein endothelial; cells,HUVECs)模型中的细胞保护作用及其对Notch信号通路的调控。方法:体外培养HUVECs,用ox ...
任开新 +7 more
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Advances in basic research, clinical diagnosis and treatment of prostate cancer in 2022 [PDF]
, 2023 About 40%-70% of newly diagnosed prostate cancer patients in China are in the stage of metastatic disease, and the spatio-temporal heterogeneity of the occurrence and development of prostate cancer and the unique metastasis pattern make it difficult to ...
PAN Jian, ZHU Yao, DAI Bo, YE Dingwei
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Protective Effect of Antioxidant Peptides Derived from Yak Milk Casein on Oxidative Stress Injury in HEK293 Cells [PDF]
, 2023 In this experiment, HEK293 cells were induced by H2O2 to establish a cell model of oxidative damage, and the optimal H2O2 concentration and treatment time were determined.
WU Dengyu, WEI Ti, MA Zhongren, SONG Li, YANG Jutian, CAI Yong, GAO Dandan
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银杏达莫对急性脑梗死患者血清补体C3、IL-6和IL-8的影响 [PDF]
Objective:To explore the effect of yinxingdamo on serum Complement C3、interleukin-6,8 in Patients with Acute Cerebral Infarction(ACI).Methods:136 cases of ACI were equally and randomly divided into two groups,one is the control group,the other group is ...
Chen, Jin-xiang, Yu, Gao-bing, Zhong, Xu
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Molecular mechanism of inhibitory effect of lipoxin A4 on estrogen-induced epithelial to mesenchymal transition (EMT) in endometriosis [PDF]
, 2016 子宫内膜异位症，简称内异症（Endometriosis，EM），是育龄妇女的常见病，它是指具有活性的子宫内膜出现在子宫腔以外所引起的一种病变。人群发病率高达10%-15%。其典型症状为不孕和疼痛，严重影响患者的生活质量和家庭和谐，尤其是高达50%的复发率，给家庭和社会带来沉重的经济负担。这一系列防治难题的根本原因在于发病机制尚不明确。解析内异症的发病机制，进而寻找新的药物靶点和安全高效的治疗方法具有重大意义。 本论文首先以临床内异症患者在位/异位子宫内膜组织及非内异症患者子宫内膜组织为研究对象 ...
吴荣锋
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抑制
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的本研究旨在探讨抑制miR-4321在改善脓毒症相关急性肾损伤（Sepsis associated acute kidney injury， SA-AKI）中的作用和机制。方法采用RT-qPCR方法检测LPS诱导的HK2细胞模型和CLP模型小鼠肾脏组织中miR-3165、miR-4270和miR-4321的表达水平。利用miR-4321-Inhibitor抑制LPS诱导的HK2细胞损伤模型中miR-4321的表达，分别通过CCK-8分析、EdU染色分析和western blotting评估miR ...
张春敏 +7 more
doaj
Detection of EGFR and COX-2 Expression by Immunohistochemical Method on a Tissue Microarray Section in Lung Cancer and Biological Significance [PDF]
, 2010 Background and objective Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2), which can regulate growth, invasion and metastasis of tumor through relevant signaling pathway, have been detected in a variety of solid tumors.
Congzhong ZHU, Juan LIU, Xinyun WANG
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