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NO吸入对肝移植急性肺损伤大鼠肺组织iNOS?IL-1β及IL-6的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 观察一氧化氮(NO)吸入对肝移植急性肺损伤大鼠肺组织诱导型NO合酶(iNOS)?白细胞介素-1β(IL-1β)?白细胞介素-6(IL-6)水平的影响与意义?【方法】 选用SD大鼠24只,按随机数字表法分为对照组(C组)?自体原位肝移植组(M组)和NO吸入组(T组),每组8只?对照组开腹游离肝叶后即关腹,后两组行大鼠自体原位肝移植?对照组及自体原位肝移植组术后于室内吸空气,NO吸入组术后即放入特制的密封盒内(NO体积分数为20 × 10-6)?手术结束后8 h行肺脏病理检查,测定肺组织干湿质量比(
罗晨芳
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Zhongguo shiyan zhenduanxue, 2015 目的观察和分析2型糖尿病（DM）合并糖尿病肾病（DN）患者血清IL-2、IL-8水平的变化及其临床意义。方法选取2型DM患者120例作为研究对象,根据其尿白蛋白排泄率（UAER）水平将其分为DM组（UAER200μg/min,共纳入41例）,选取同期体检结果正常的健康人40例作为对照组。对四组研究对象的血清IL-2水平和血清IL-8水平进行检测和比较。结果对照组研究对象的血清IL-2水平显著高于DM组 ...
杜立树, 平龙玉, 张曼俐
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Zhongguo shiyan zhenduanxue目的 探究肝硬化合并腹水患者的发病危险因素，为肝硬化合并腹水的防治提供依据。方法 选取健康人68名(健康对照组)、肝硬化代偿期患者70例(肝硬化代偿组)和肝硬化失代偿期患者70例(肝硬化失代偿组)。采用酶联免疫吸附测定法(ELISA)试剂盒检测各组研究对象肝功能指标，采用流式血细胞分析仪检测各组研究对象白细胞计数(WBC)、中性粒细胞计数(NE)、血小板计数(PLT),采用16S rDNA分析各组研究对象肠道菌群情况，采用ELISA试剂盒测定各组研究对象炎症因子及内毒素水平 ...
赵洋 +4 more
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Zhongguo shiyan zhenduanxue, 2013 目的探讨Th17细胞、白介素21（interleukin 21,IL-21）因子在肺纤维化发病机制中的表达及意义。方法采用64只SD大鼠随机分为3组:肺纤维化模型组（P,n=24）、地塞米松3mg/kg干预组（D,n=16）、生理盐水对照组（N,n=24）。P、D组均采用一次性气管内注射博来霉素（Bleomycin,BLM）（5mg/kg）方法建立大鼠肺纤维化模型,N组气管内灌注等量0.9%氯化钠注射液。D组从第7天开始1次/日腹腔注射地塞米松;N、P组腹腔注射等量0.9%氯化钠注射液。造模后7、14 ...
于永江 +5 more
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[Research progress on toxic shock syndrome due to group A <i>Streptococcus</i> infection in children]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiWang HY, Zhou W, Huang LS.
europepmc +1 more source
[Sulforaphane reduces reactive astrocyte-mediated neuron apoptosis <i>in vitro</i> by inhibiting the MAPK/NF-κB signaling pathway in Aβ42 oligomer-activated astrocytes]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang S +5 more
europepmc +1 more source
[Aerobic exercise regulates macrophage polarization and improves insulin resistance in mice: the mediating role of miR-221-3p]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi N, Zhang L, Guo Q, Zhou Y, Liu C.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 观察一氧化氮(NO)信号途径在膜雌激素受体介导的内皮祖细胞(EPCs)增殖和凋亡中的作用65377; 【方法】 在培养的EPCs上,分别使用E2-BSA65380;或加雌激素受体阻断剂ICI 182,78065380;PI3K抑制剂LY294002和NOS抑制剂l-NAME,利用噻唑蓝(MTT)法检测细胞增殖活性(10组,n = 9),利用化学比色法测定NO的含量(6组,n = 6),Hoechst 33258染色观察EPCs凋亡(8组,n = 5 ...
doaj
[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhao B +8 more
europepmc +1 more source
Objective To investigate the application effect of vacuum sealing drainage combined with continuous irrigation of compound Sihuang solution in the wound care of diabetic foot ulcers. Methods A prospective study was conducted.
CHEN Huibing (陈惠冰) +1 more
core +1 more source