, 2013 【目的】 探讨姜黄素预先给药对兔单肺通气导致的肺炎性损伤的影响及可能机制。【方法】 将12只健康新西兰白兔随机分为2组,每组6只:开胸单肺通气+对照剂组(组1)和开胸单肺通气+姜黄素组(组2)。两组兔经腹腔注射分别预先给予对照剂和姜黄素,每天早晚各1次。连续给药7 d后,两组兔均经口插入单腔气管导管行右侧单肺通气,并左胸开一小口模拟手术操作。分别于机械通气前(T0)及实验结束前(T4)采集动脉血行血气分析,计算氧合指数。处死动物后,行右侧支气管肺泡灌洗测定髓过氧化物酶 (MPO)含量及中性粒细胞数量 ...
李慧婷
core
[Advances in targeted therapies for chronic spontaneous urticaria]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanZhou L, Hu C, Wang S, Zhang R.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban目的探讨NR2F1分子介导的休眠卵巢癌（OC）细胞对化疗药物耐药的分子机制。方法利用GEPIA数据库分析OC患者中NR2F1分子的表达及其与患者总生存期的关系；采用慢病毒体外转染构建核受体亚家族2组F1（NR2F1）过表达的OC细胞株和对照细胞； CCK-8试剂盒检测OC细胞的增殖；实时荧光定量PCR（qRT-PCR）分析OC细胞中休眠相关分子基因mRNA的表达水平；蛋白质免疫印迹试验分析相关分子蛋白表达水平；台盼蓝排除法分析不同化疗药物作用下OC细胞的活力；Annexin V-FITC ...
郭宁, 居颂文
doaj
[Identification of efferocytosis-related genes in osteoarthritis and prediction of traditional Chinese medicines based on bioinformatics and machine learning]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXiang K +5 more
europepmc +1 more source
Zhongguo shiyan zhenduanxue, 1998 目的探讨ＩＬ－６和ＩＬ－８在监测胎膜早破中的作用。方法采用酶联免疫吸附实验对４６例胎膜早破孕妇母血清、羊水中ＩＬ－６和ＩＬ－８水平进行监测，并以正常足月妊娠孕妇２０例做对照组。结果胎膜早破孕妇母血清中ＩＬ－６、８和羊水中ＩＬ－６、８水平均较正常足月妊娠组高，差异显著（Ｐ＜０．０１；Ｐ＜０．０５）；随着破膜时间延长母血中ＩＬ－６、８和羊水中ＩＬ－６、８有增加趋势；绒毛羊膜炎患者１３例，其母血、羊水中ＩＬ－６和ＩＬ－８水平均明显高于非绒毛羊膜炎患者（Ｐ＜０．０５）。结论测定胎膜早破孕妇羊水ＩＬ－６和ＩＬ ...
doaj
[Selenocystine inhibits colon cancer cell growth by promoting reactive oxygen species generation to trigger oxidative damage]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoSong Q +8 more
europepmc +1 more source
[Liver-bone axis: novel mechanisms and strategies for MAFLD regulation]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWang YW, Yan XZ, You H, Yang AT.
europepmc +1 more source
[Oral homeostasis imbalance under hypoxia]. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiXu Y, Wang S, Zhou J.
europepmc +1 more source
[Niranthin ameliorates Crohn's disease-like colitis in mice via antagonizing intestinal epithelial cell apoptosis and regulating intestinal Th1/Th2 immune homeostasis]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoWen H, Lin J, Zuo L, Liu M.
europepmc +1 more source
[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]
Zhonghua Gan Zang Bing Za ZhiZhao RQ +9 more
europepmc +1 more source