, 2001 Mx蛋白是干扰素诱导表达的蛋白家族中的成员 ,当机体和细胞受病毒感染或诱生剂处理时产生。Mx蛋白和其它干扰素诱导蛋白一起构成宿主细胞的抗病毒状态 ,以达到抗病毒的目的。研究表明 ,Mx蛋白具有抗病毒活性 ,还可能与其它基本生命活动如发育或分化 ,蛋白质分送和生长有关。在鱼类也发现多种Mx蛋白 ,具有Mx蛋白家族的共有特征 :在肽链末端有一个三联ATP/GTP结合区和发动蛋白家族的结构特征序列 ;在蛋白C端存在使Mx蛋白形成三聚体的Leu拉链结构以及定位信号。但是迄今没有发现鱼类Mx蛋白的抗病毒活性 ...
张义兵,桂建芳
core
[Protective effects and underlying mechanisms of bone marrow mesenchymal stem cells-derived apoptotic extracellular vesicles in acute kidney injury]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiLin Z, Chen J, Lin T, Liu S, Liu J.
europepmc +1 more source
[Berberine attenuates necrotizing enterocolitis-associated brain injury via the TLR4/MyD88/NF-κB/NLRP3 pathway]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiChen JQ +4 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 应用乙腈(ACN)预处理血清的方法,对肝细胞癌(HCC)患者的血清进行蛋白质组分析,寻找与HCC发病相关的蛋白质65377; 【方法】 收集原发性HCC患者和健康人的血清各12例,首先使用乙腈预处理,然后去除白蛋白和免疫球蛋白等高丰度蛋白质,再进行双向电泳(2-DE)分析,筛选HCC与健康对照血清中有显著性差异的蛋白质斑点,并进行MALDI-TOF/TOF质谱鉴定65377; 【结果】 血清经0%65380;20%和30%浓度的乙腈预处理后,进行2-DE分析发现蛋白质斑点的检出数量分别为532
doaj
[<i>Liuwei Dihuang</i> Pill regulate osteoclast membrane fusion to improve postmenopausal osteoporosis in mice: the CLCF1/NFATc1 signaling axis as a therapeutic target]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZheng R, Xie L, Huang X, Ge J.
europepmc +1 more source
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Nan Fang Yi Ke Da Xue Xue BaoLi C +6 more
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[Systemic Reprogramming of Cellular Senescence: Coordinated Regulation of Metabolism, Epigenetics, and Proteostasis]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZheng Y, Liu Q, Wang R, Sun C.
europepmc +1 more source
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Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za ZhiWang SS +6 more
europepmc +1 more source
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Zhonghua Gan Zang Bing Za ZhiZhou D, Gao XQ, Zhang LT.
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Sheng Wu Yi Xue Gong Cheng Xue Za ZhiWang Q, Zhao S, Wang H, Li X, Ren W.
europepmc +1 more source