Results 1 to 10 of about 1,379 (117)
Zhongshan Daxue xuebao. Yixue kexue ban, 2023 目的探讨RNA结合基序单链相互作用蛋白3（RBMS3）在上皮性卵巢癌（EOC）组织中的表达，及其与EOC组织的临床病理特征和预后的关系。方法选取蚌埠医学院第一附属医院2015年1月~2019年12月经术后病理证实的110例EOC石蜡包埋组织及73例上皮性卵巢良性肿瘤石蜡包埋组织，利用抗RBMS3的多克隆抗体进行免疫组织化学染色（IHC），检测各组织中RBMS3的表达情况，并分析RBMS3的表达与EOC临床病理参数及预后的相关性。结果在EOC组织与上皮性卵巢良性肿瘤组织中RBMS3均表达 ...
邢瑞丽 +5 more
doaj +3 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】探讨JAK/STAT信号转导途径负调控子SHP-1基因启动子区域CpG岛异常甲基化在B细胞淋巴瘤中的意义。【方法】收集存档石蜡包埋组织标本61例(52例B细胞非霍奇金淋巴瘤标本,9例良性增生淋巴结标本),健康人外周血单个核细胞DNA标本15例,用甲基化特异性PCR(methylation-specific PCR,MSP)和非甲基化特异性PCR(unmethylation-specific PCR,un-MSP)检测SHP-1启动子区域CpG岛甲基化状态,MSP、un-MSP和RT ...
汪清铭 +5 more
doaj +2 more sources
血小板源性生长因子受体α突变型胃肠间质瘤的临床病理特征及预后分析 [PDF]
, 2021 目的探讨血小板源性生长因子受体α（PDGFRA）突变胃肠道间质瘤（GIST）中PDGFRA基因的突变状况、临床病理特征及预后因素，为生物靶向治疗提供依据。方法收集 2015 年1月至 2020 年11月期间中山大学肿瘤防治中心收治的经病理确诊为GIST，且原发肿瘤组织通过Sanger测序证实存在PDGFRA基因12或18号外显子突变的40例患者石蜡标本。采用免疫组化检测GIST中CD117、CD34、DOG-1及Ki-67表达情况。收集患者临床病理特征资料，回顾性分析影响 PDGFRA 突变型GIST ...
刘小云 +5 more
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Progress in clinical management of cancer of unknown primary based on molecular testing at 2023 ESMO [PDF]
, 2023 Cancer of unknown primary (CUP) is a metastatic syndrome with an unidentifiable primary tumor even after comprehensive clinical and pathological investigations, accounting for approximately 2%-5% of all newly diagnosed cancers.
ZHANG Xiaowei, LIU Xin, LUO Zhiguo
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The standardization of immunohistochemical detection and interpretation of CD30 expression in lymphomas [PDF]
, 2023 CD30 can be expressed in a variety of lymphoma subtypes, among which classical Hodgkin lymphoma (CHL) and anaplastic large cell lymphoma (ALCL) are the most common ones.
CD-Positive Lymphoma Pathology Expert Group
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Change of transcription factor EB activity and autophagy in hippocampus of type 2 diabetic encephalopathy mice [PDF]
, 2023 Objective·To investigate the changes of transcription factor EB (TFEB), the activity of the upstream proteins and autophagy in the hippocampus of mice with type 2 diabetic encephalopathy.Methods·Twenty healthy 8-week-old male C57BL/6J mice were randomly ...
CHEN Yixin +3 more
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Retrospective study on MGMT methylation status and its clinical significance in gliomas [PDF]
, 2023 Background and purpose: Glioma is a common malignant tumor of central nervous system with poor prognosis. Postoperative concurrent chemoradiotherapy with temozolomide (TMZ) is the main treatment for glioma.
JIANG Lin, LIU Qiying, JIA Liqing, ZHANG Jing, CHANG Heng, XUE Tian, REN Min, BAI Qianming, ZHU Xiaoli, ZHOU Xiaoyan
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Process of Forensic Medicine in DNA Identification of Aged Human Remains [PDF]
, 2023 Skeleton and teeth are important biological samples. Due to their special structure and strong ability to resist degradation, they are ideal biological materials to retain DNA under natural condition.
Lu CHEN, Zhe ZHOU, Sheng-qi WANG
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Guidelines for breast cancer diagnosis and treatment by China Anti-cancer Association (2024 edition) [PDF]
, 2023 According to the latest data released by the International Agency for Research on Cancer of the World Health Organization (WHO), breast cancer has become the malignant tumor with the highest incidence rate around the world, seriously endangering the ...
The Society of Breast Cancer China Anti-Cancer Association, Breast Oncology Group of the Oncology Branch of the Chinese Medical Association
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Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]
, 2023 With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.
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