Results 11 to 20 of about 31,694 (216)

Study of N-Phosphorylation on Peptide and Protein-- Preparation of Phosphoramidate and Application of anti-Phosphoarginine Antibody [PDF]

open access: yes, 2016
蛋白质有诸多翻译后修饰(post-translationalmodifications,PTMs),包括甲基化、泛素化、乙酰化和磷酸化等等。其中,磷酸化修饰被认为是调控蛋白质功能的重要“开关”,是细胞内信号转导的关键机制,与人类多种疾病的发生密切相关。目前,天然蛋白质中共发现有9种氨基酸可以被磷酸化,其中包括以P-O键连接的磷酸酯类修饰,如磷酸化丝氨酸、苏氨酸和酪氨酸;以P-N键连接的磷酰胺类修饰,如磷酸化组氨酸、精氨酸和赖氨酸;酰基酸化是通过天冬氨酸或谷氨酸的磷酸化形成的,而S ...
孙影
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Construction of CoP/Mn2P Heterojunctions via One‐Step Phosphorization Coupled With Hollow Hard Carbon Spheres as Supports: Enabling Ultrastable Long‐Cycle Sodium‐Ion Anodes Over a Wide Temperature Range

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Driven by global energy transition and sustainability, sodium‐ion batteries (SIBs) have emerged as key alternatives to lithium‐ion batteries for low‐to‐medium energy storage, because of abundant sodium resources and low cost. However, their commercialization is hindered by the lack of anodes with high capacity, fast kinetics, and long‐term ...
Shuang‐Lin Cai   +13 more
wiley   +1 more source

The Application of Long Circulation Liposomes Combined with Phospholipid Complex or Calcium Phosphate Coated- Mesoporous Silica in Anti-Tumor Therapy [PDF]

open access: yes, 2016
纳米药物传递系统种类多样,优势明显。良好的纳米药物传递系统能够降低药物的毒副作用,延长药物在体循环时间,缓控释药物以及拥有良好的靶向性能等特点,使得其具有更好的疗效和治疗指数。然而在抗癌药物载体的研究中,许多药物传递系统的细胞摄取效果并不佳,若长循环脂质体运用在纳米药物传递系统中,势必能够增加药物载体的生物相容性,延长药物在体循环时间。 本课题研究了长循环脂质体在“软物质”和“硬颗粒”两种模型纳米药物载体中的应用,分别对其形态、粒径、电位等理化性质进行了表征,对其稳定性、细胞毒性 ...
吴泓杰
core  

Cancellous Bone‐Like Sr‐Doped Hydroxyapatite/Gelatin Porous Scaffolds With Nanofibrous Architecture and Ion Release for Promoting Osteogenesis

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Constructing a porous scaffold with the essential features of natural cancellous bone, including structural architecture and biochemical cues, is one of the pivotal factors for effective bone regeneration. In this study, a biomimetic composite porous Gelatin fibrous scaffold (SrHA/Gelatin) incorporating ultralong strontium‐doped hydroxyapatite
Yin‐Chuan Wang   +8 more
wiley   +1 more source

ROS via promoting RIP1 auto-phosphorylation to enhance TNF-induced necrosome formation and subsequent necroptosis [PDF]

open access: yes, 2015
活性氧(ReactiveOxygenSpecies,ROS)的产生存在于生物体的众多生理病理过程中。大量的实验数据表明,活性氧还参与到了细胞凋亡和程序性坏死的进程里。丁基羟基苯甲醚(Butylatedhydroxyanisole,BHA)是公认的活性氧清除剂,异戊巴比妥(Amytal)是线粒体上电子传递到泛醌的抑制剂,二者都曾被广泛报道,可以抑制或者延缓肿瘤坏死因子(TumorNecroticFactorα,TNF-α)诱导的小鼠成纤维细胞系L929的程序性细胞坏死。然而 ...
张荧荧
core  

Elevation, soil pH and calcium availability shape regional and local scale spatial patterns of PhoD gene abundance in tropical and subtropical forests

open access: yesFunctional Ecology, Volume 40, Issue 4, Page 983-1000, April 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Organic phosphorus mineralization is a critical process in the phosphorus cycle, governing phosphorus bioavailability for plants. The PhoD gene, which encodes the key enzyme alkaline phosphatase, serves as a valuable biomarker for this process.
Sandhya Mishra   +3 more
wiley   +1 more source

有机-无机配施对盐渍土壤水稻生长及养分利用的影响

open access: yesShuitu Baochi Xuebao, 2019
针对滨海盐渍化土壤水稻种植过程中根系生长受盐碱胁迫,导致养分利用率低的问题。采用田间试验研究了有机肥与磷肥配施对滨海盐渍化土壤水稻不同生育期根系生长、水稻产量及养分利用率的影响。试验采用双因素设计,3个碳水平:(1)C0,无碳;(2)C1:低碳,450 kg/hm2;(3)C2:高碳,900 kg/hm2;3个磷水平:(1)P0:无磷;(2)P1:低磷,P2O5 64 kg/hm2;(3)P2:高磷,P2O5 128 kg/hm2。结果表明,在水稻成熟期,低碳低磷(T5 ...
陈猛猛   +7 more
doaj  

Acid‐Etched Co‐Vacancy‐Tunable CoFeP/N,P‐Codoped Carbon Nanocages for Highly Efficient Alkaline Water Electrolysis

open access: yesRare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Efficient and durable bifunctional electrocatalysts are vital for scalable water electrolysis. Here, we realize cobalt‐vacancy (Covac) engineering in CoFeP supported on N,P‐codoped carbon nanocages (Co1‐vacFeP/NPC) through a simple route comprising a CoFe Prussian blue analog precursor, phosphidation–pyrolysis, tannic‐acid etching, and a ...
Yuan‐Liang Yuan   +6 more
wiley   +1 more source

福州不同农田土地利用类型土壤碳氮磷生态化学计量学特征

open access: yesShuitu Baochi Xuebao, 2019
为阐明不同土地利用类型土壤碳(C)、氮(N)、磷(P)生态化学计量学特征,对福州农田不同土地利用类型(水稻田、菜地和茉莉园)下的土壤全碳(TC)、全氮(TN)、全磷(TP)含量及其生态化学计量学特征进行测定和分析。结果表明:土壤TC含量均值基本表现为水稻田 > 菜地 > 茉莉园(P 菜地 > 茉莉园(P 水稻田 > 茉莉园 ...
刘旭阳   +5 more
doaj  

Flame Retardant Modification of Epoxy Using Phosphorus-containing POSS-based Polymers [PDF]

open access: yes, 2015
环氧树脂因其具有良好的粘结性、化学稳定性、低收缩、优异的机械性能、易加工成型和成本低廉等优点,而广泛应用于粘结剂、涂料及电子封装等领域,但是由于环氧树脂存在内应力大、质脆,耐热性及阻燃性能不足而使得其应用受到限制。传统含卤素尤其是含溴阻燃剂虽被证明有很好的阻燃效果并得到广泛应用,但研究发现其在燃烧时会生成有毒物质,使得含卤阻燃剂的使用受到限制。建立新型无卤、无毒的环氧阻燃体系已成为科研工作者关注的研究热点之一。 本文以DOPO(9,10-二氢-9-氧杂-10-磷杂菲-10-氧化物 ...
陈国荣
core  

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