Results 31 to 40 of about 53,621 (172)

The role of TNFAIP8 family in gastric cancer and heart transplantation [PDF]

open access: yes, 2016
摘要 目的:TIPE及TIPE2是TNFAIP8(Tumornecrosisfactor-αinducedprotein-8,TIPE,TNFAIP8)家族的重要成员,TIPE是调控凋亡进程的重要分子,本研究之一是应用TIPE不同表达的BGC823细胞株建立胃癌裸鼠移植瘤模型,观察TIPE对移植瘤生长的影响;同时收集并检测胃癌临床标本TIPE的表达特点,分析TIPE与胃癌临床病理特征的关系,明确TIPE与胃癌生物学行为的关系及对胃癌生长的影响。 TIPE2为免疫负性调控因子,对免疫稳态的维持起重要作用 ...
洪诗福
core  

Deciphering fire tolerance of trees at the Amazonia–Cerrado transition by trait‐based approach: Implications from species to communities

open access: yesAmerican Journal of Botany, Volume 112, Issue 10, October 2025.
Abstract Premise Understanding how fire impacts trees is essential for predicting the effects of novel fire regimes on plant diversity in the transition between the world's two most diverse biomes, the Cerrado and the Amazonia. Here we addressed knowledge gaps regarding physiological damage and mortality in transitional species within fire‐prone ...
Wesley Jonatar A. Cruz   +6 more
wiley   +1 more source

The effection of everolimus on hamster-to-rat concordant heart xenotransplantation [PDF]

open access: yes, 2016
背景:器官移植是解决很多终末期疾病最有效的手段,然而器官短缺限制着器官移植术的推广。异种移植是最有可能快速解决器官短缺问题的途径之一。虽然异种移植的超级性排斥反应已经因分子生物学技术的应用而极大减轻,但异种移植的急性排斥反应、延迟性排斥反应等仍旧没有克服。新型免疫抑制剂的开发可能有助于克服这些类型的免疫排斥反应。依维莫司是雷帕霉素衍生物,是一种可用于抗移植排斥的免疫抑制药物,动物实验和临床资料表明它可延长同种器官移植物生存期。依维莫司对免疫系统具有多种调节作用 ...
付嘉钊
core  

Reproductive outcome after frozen embryo transfer with hormone replacement therapy according to luteal‐phase support protocol: systematic review and network meta‐analysis of randomized controlled trials

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 4, Page 422-432, October 2025.
ABSTRACT Objective To compare reproductive outcome between luteal‐phase support (LPS) protocols for frozen embryo transfer (FET) cycles with hormone replacement therapy (HRT). Methods A search was conducted in MEDLINE, Scopus, LILACS, EMBASE, Scielo.br, PROSPERO, CINAHL, PsycINFO, AMED, ClinicalTrials.gov, ICTRP, the Cochrane Library and conference ...
A. Etrusco   +11 more
wiley   +1 more source

Combination CXCL9 Antibodies with FTY720 Prolongs the Survival of Cardiac Retransplantation Allografts in a Rat Model [PDF]

open access: yes, 2015
实验目的 趋化因子的基因表达上调和随之发生的T淋巴细胞在移植物中的募集发生在 同种异体器官移植急性排斥反应和器官移植血管病变的早期。在本研究中我们尝 试使用联合趋化因子CXCL9抗体和FTY720的免疫抑制方案,抑制记忆性T细胞 的增殖,调节T细胞细胞因子的分泌,加速淋巴归巢,减少再次心脏移植物中的 淋巴细胞浸润,从而延长大鼠再次心脏移植物的存活时间。 实验方法 BN大鼠作为实验受体,LEW大鼠作为实验供体。颈部套管法异位心脏移植术 后4周进行再次腹部异位心脏移植术。根据不同的免疫抑制方案将大鼠分为四组。
马腾
core  

Using online reports of seahorse seizures to track their illegal trade

open access: yesConservation Biology, Volume 39, Issue 5, October 2025.
Abstract Illegal wildlife trade (IWT) is a persistent and extensive threat to global biodiversity. Hundreds of marine fish species are subject to regulation under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), but it is unclear how much protection species gain from CITES because information on marine fish ...
Sarah J. Foster   +3 more
wiley   +1 more source

红外热像扫描技术在组织工程皮肤移植修复中的应用

open access: yesZhongguo shiyan zhenduanxue, 2004
目的 探索红外热像扫描技术在组织工程皮肤移植修复中应用的可能性。方法 在组织工程皮肤对大面积皮肤缺损动物 (裸鼠 )进行移植修复的不同时间 ,应用红外热像扫描仪对移植修复区进行动态观察。结果 在移植术后第 7天 ,热像图上移植区与正常皮肤温差明显 (>0 7℃ ) ;在移植的第 14天 ,移植区与周围正常皮肤的温差变小(
乔锋利   +5 more
doaj  

Thalidomide combined with co-stimulatory molecules blockade prolongs survival of cardiac allografts in alloantigen-primed mice [PDF]

open access: yes, 2015
目的:体内预存的各种记忆细胞是器官移植中的重要障碍。记忆细胞对侵入的病原体产生强烈的免疫反应,但同时会导致移植物发生排斥。研究发现,沙利度胺在初次器官移植中具有抑制免疫排斥反应的作用,但其作用机制仍不明确。沙利度胺在器官移植中的潜在作用,很有可能使其成为作用于新靶点、高效低毒的免疫抑制剂。这里,我们拟研究沙利度胺联合共刺激分子阻断剂对皮肤预致敏小鼠心脏移植物生存期的作用,并探讨其在免疫记忆中的作用机制。 方法:首先通过同种异体皮肤移植得到预致敏小鼠,然后随机将皮肤预致敏小鼠分成4组,每组6只。对照组 ...
朱茂述
core  

A unifying framework for understanding how edge effects reshape the structure, composition and function of forests

open access: yesNew Phytologist, Volume 248, Issue 2, Page 529-541, October 2025.
Summary Due to widespread deforestation and habitat fragmentation, today most of the world's forests lie within 1 km of an edge. Forests near edges are warmer, drier, receive more light, and are more exposed to wind and other disturbances than intact forests, profoundly altering the demographic processes that drive their dynamics.
Rebecca Banbury Morgan, Tommaso Jucker
wiley   +1 more source

Reoccurrence of Dust Storms in South Asia and Their Implications for Vegetation Health 南亚沙尘暴的再次出现及其对植被健康的影响

open access: yesIntegrative Conservation, Volume 4, Issue 3, Page 362-380, September 2025.
Occurrences of dust storms and long‐distance movement of dust across landscapes is constantly increasing in south Asia. This dust is expected to have profound impact on vegetation health and sustainability as dust may contribute to nutrient budgets of the forest ecosystems, while it could impart various stresses to the plants.
Shree P. Pandey   +2 more
wiley   +1 more source

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