Results 81 to 90 of about 2,414 (136)

[Exosomes from folic acid-treated subpatellar fat pad-derived mesenchymal stem cells promote M2 polarization of macrophages <i>in vitro</i>]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
Wang Z   +9 more
europepmc   +1 more source

[Clinical characteristics of late-onset circulatory collapse in preterm infants]. [PDF]

open access: yesZhongguo Dang Dai Er Ke Za Zhi
Huang Y   +5 more
europepmc   +1 more source

[Multidisciplinary diagnosis and treatment of temporal bone cholesteatoma complicated with brain abscess]. [PDF]

open access: yesLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Yang L, Lu J, Wu M, Tang L.
europepmc   +1 more source

The synergistic anticancer effect of Lipo-Dox and perforin on colon cancer cell, CT26

open access: yes
[[abstract]]穿孔素是一種經由活化態細胞毒殺型T淋巴球及自然殺手細胞所表現的分泌型蛋白質。穿孔素在毒殺細胞的機制中為一重要的物質,其作用為插入目標細胞之細胞膜並在細胞表面形成孔洞,造成細胞傷害。在先前的研究中,我們探討利用穿孔素配合抗癌藥物Doxorubicin的協同效用對於毒殺癌細胞的可能性。穿孔素表現載體經由CMV啟動子所驅動,並將表現載體轉染至小鼠大腸癌細胞株,CT26。透過MTT分析的方式評估不同表現載體穿孔素毒殺效率 ...
Li, Yan-Qing, 李彥慶
core  

[Helicid alleviates depression-like behavior in rats with chronic unpredictable mild stress through the NCALD/sGC/cGMP/PKG axis]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
DU X   +8 more
europepmc   +1 more source

Perforin Expression Driven by Survivin Promoter Inhibits Tumor Growth

open access: yes
[[abstract]]生存蛋白在成熟的正常組織表現低落,但卻廣泛地、大量地表現於癌細胞中,為著名的IAP (Inhibitor of Apoptosis Protein) 家族成員之一。功能歸納出有三類,分別是抑制細胞凋亡、參與細胞分裂和抗藥性的產生。因為生存蛋白幾乎不在正常細胞表現,已有許多研究利用位於生存蛋白基因上游的啟動子進行基因治療。在生存素啟動子下游接上可對癌細胞產生細胞毒性的蛋白之基因,然後將此載體送入癌細胞內,使細胞大量表現此一蛋白質,而達到抑癌的結果。 穿孔素為細胞內重要的毒殺蛋白 ...
Chu, Ying-rui, 朱映瑞
core  

[Application and research progress of metal-organic framework materials in skin repair]. [PDF]

open access: yesSheng Wu Yi Xue Gong Cheng Xue Za Zhi
Ma S, Wu W, Liu H, Liu M, Xing F.
europepmc   +1 more source

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