Results 41 to 50 of about 184,145 (152)
Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Platinum‐based electrocatalysts are fundamentally constrained by strong oxygen binding, which restricts the oxygen reduction reaction (ORR) kinetics, and by severe CO poisoning, which hinders the methanol oxidation reaction (MOR). To address these limitations, we synthesized PdPtRuIrRhNi high‐entropy alloy (HEA) mesoporous nanotubes that ...
Hong Pan +6 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】利用聚合酶链反应(PC R)技术对Wilson 病(WD)基因进行体外定点突变的研究。【方法】采用PCR 定点 突变技术, 首先设计两对引物, 将突变位点设计在引物上, 通过重叠延伸法两次PCR 扩增, 扩增片段上含有所需要的突变位 点, 最后将扩增片段克隆入pRc/ CMV 载体中。【结果】DNA 测序表明在预期位点已经发生突变,WD 基因第778 位密码子由 精氨酸(Arg)残基突变为亮氨酸残基(Leu), 用PCR 定点突变技术成功构建Wilso n 病基因突变体。【结论】PCR ...
闫振文 +4 more
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Concurrent Crises and Non‐State Service Provision
Risk, Hazards &Crisis in Public Policy, Volume 17, Issue 3, September 2026.ABSTRACT Concurrent crises represent a significant challenge for disaster and public health governance. Activated in response to one threat, governing institutions may be distracted or stretched thin during an emergent crisis. In such crises, governments and communities rely heavily on non‐state service providers such as non‐profit organizations and ...
Daniel Sledge, Herschel F. Thomas
wiley +1 more source
四川大学学报. 自然科学版, 2002 G6PD是磷酸戊糖旁路代谢的限速酶 ,也是重要的看家酶 .G6PD缺乏症是人类常见的遗传性疾病 .作者应用突变特异性扩增系统 (ARMS) ,对 2 1例G6PD缺乏症患儿进行基因检测 .结果在2 1例患儿中检出G1388A突变 7例 ,G1376T突变 4例 ,A95G突变 3例 ,未定型 7例 .成都常见的G6PD基因突变型为中国人中常见突变型 ,分析四川人群G6PD基因突变型 ,估计基因突变频率 ,可为四川省G6PD缺乏症的临床防治提供理论依据 .
杨春蕾 +4 more
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Zhongguo shiyan zhenduanxue, 2021 目的探讨肝硬化患者血浆游离DNA(cfDNA)中TERT基因-124(C/T)和-146(C/T)热点突变率及其突变与临床指标相关性。方法纳入航天中心医院2019年10月-2020年11月肝硬化患者80例,收集患者临床基本资料。EDTA抗凝全血分离500μL血浆提取cfDNA。TERT热点突变检测采用ARMS-qPCR方法。结果在80例肝硬化患者血浆cfDNA中,检测到TERT热点突变6例(7.5%),其中-124(C/T)4例(5%),-146(C/T)2例(2.5%)。与非突变组比较 ...
薛晓霞, 何美琳, 梁国威
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World Medical &Health Policy, Volume 18, Issue 3, September 2026.ABSTRACT Confrontational violence still puts catastrophic burdens on children, with 2024 being the highest recorded levels of displacement, malnutrition, injury, and deprivation in contemporary humanitarian history. Children's surgical care is still grossly underrepresented in health responses worldwide in the prevention of avoidable deaths and long ...
Gaurav Chanderprakash Mittal +4 more
wiley +1 more source
, 1997 介绍了基于细观非线性动力学模型的研究所取得的进展。发现系统显示一种共性特征，称为演化诱致突变，即演化模式从整体稳定向灾变性模式转变，宏观破坏的样本个性行为 ...
白以龙, 柯孚久, 夏蒙棼
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Functional Ecology, Volume 40, Issue 9, Page 2843-2860, September 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract Drylands are mainly structured by both vascular plants and biological soil crusts (biocrusts), the latter often regarded as a self‐organizing component of these ecosystems.
Haoran Luo +13 more
wiley +1 more source
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT The electrocatalytic co‐reduction of CO2 and nitrate (NO3− ${\text{NO}}_{3}^{-}$) to synthesize urea presents a sustainable alternative to traditional industrial processes, yet its efficiency is fundamentally limited by the kinetically mismatched activation and coupling of CO2 and NO3− ${\text{NO}}_{3}^{-}$.
Jiayu Liu +9 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的对已明确基因突变的轻型β-珠蛋白生成障碍性贫血患者的红细胞参数进行比较分析,探讨β-珠蛋白基因的突变类型与红细胞参数的相关性。方法分析118例已知基因突变的轻型β-珠蛋白生成障碍性贫血患者的红细胞平均容积、红细胞平均血红蛋白含量、红细胞平均血红蛋白浓度、红细胞体积分布宽度标准差、红细胞体积分布宽度变异系数,对这些参数依据突变类型进行比较。结果在已知β-珠蛋白基因突变中,携带codon41/42（-TTCT）突变的患者红细胞平均容积、红细胞平均血红蛋白含量及红细胞平均血红蛋白浓度高于其它突变患者 ...
彭运生 +4 more
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