Correlation between myocardial work and disease activity in rheumatoid arthritis patients with preserved left ventricular ejection fraction: a retrospective study based on non-invasive pressure-strain loop:. [PDF]
Early cardiac damage is very common in RA patients, but it is usually subclinical. Therefore, finding a non-invasive method for the early detection and treatment of cardiac damage in autoimmune diseases is particularly important.早期diac dam年龄在 RA 患者中很常见 ...
Yu X, Xi J, Wu J, Song R.
europepmc +2 more sources
[Cheng's Juanbi Decoction Inhibits Rheumatoid Arthritis Pathology by Blocking the WTAP-Wnt7b-Wnt/β-Catenin Signaling Axis]. [PDF]
目的 采用胶原诱导的关节炎(collagen-induced arthritis, CIA)小鼠和类风湿关节炎(rheumatoid arthritis, RA)患者的成纤维样滑膜细胞(fibroblast-like synoviocytes, FLSs)研究程氏蠲痹汤(CSJBD)的抗RA作用,并探讨其作用机制。 方法 体内实验:实验动物为体质量17~20 g的雄性C57BL/6小鼠,构建CIA模型。将小鼠分为正常组、模型组(CIA)、模型+CSJBD-L组(8.1 g/kg)、模型+CSJBD-M组(
Wu Y +8 more
europepmc +2 more sources
腕关节镜外科是近年来才兴起的新技术。本文报道了腕关节镜下滑膜切除术治疗20例共30个腕关节类风湿性关节炎的经验。疗效满意。文章并就腕关节镜的诊断作用、具体操作方法、滑膜切除术在治疗类风湿性关节炎中的地位、关节镜下滑膜切除术的优点、尤其是不影响关节活动功能的原因,进行了详细的讨论。
徐锦森
doaj +2 more sources
Research Progress in the Application of Proteomics andMetabolomics in Bee Products [PDF]
Bee products are gaining increasing popularity among consumers for their high nutritional value and various biological activities. However, adulteration is becoming a prominent problem in the production and sale of bee products, and the mechanisms ...
Congcong LIN, Qun LU, Rui LIU, Yan ZHAO
core +1 more source
类风湿关节炎(Rheumatoid arthritis,RA)是以侵蚀性、对称性多关节炎为主要表现的慢性、全身性自身免疫性疾病, 最终发展为关节畸形和功能丧失, 并损害心、肺、肾、神经等器官[1]。我国RA的发病率为0.32%~0.36%。该病具有病程长、复发率高、致残率高等特点,在临床上又被称为\"不死癌症\"[2],严重危害患者健康。该病治疗的目的是缓解疼痛,提高关节活动度,阻止残疾的发生。康复功能锻炼是降低国家自然科学基金资助项目(编号 ...
刘丽静 +6 more
core +1 more source
Bullous pemphigoid complicated with macroamylasemia: a case report [PDF]
High amylase level is a typical sign of acute pancreatitis. However, it can also be found in other diseases. In the article, a case of persistent elevation of amylase level for over 1 year was reported.
Zhang Feiya, Mu Manna, Lin Ying, Yang Yi, Zhu Donglin, Jiang Baiquan, Zhang Guochao, Mu Panwei
core +1 more source
目的了解医院口服非甾体类抗炎药(NSAIDs)的使用情况及用药趋势,为临床合理用药提供一定的参考依据。方法对2011-2015年解放军第175医院口服NSAIDs的主要品种、销售金额、用药频度(DDDs)以及药品的销售金额和用药频度的排序比值(B/A)等情况进行统计分析。结果 5年来,该院口服NSAIDs的销售金额与用药频度逐年呈上升趋势,塞来昔布在单药销售金额排序最高;阿司匹林肠溶片在DDDs排序中居于首位;且B/A平均值最高,5年来均大于2 ...
杨建锋, 费燕, 赵佳丽, 陈尚瑜
core +1 more source
Efficacy of Two Drug Regimens in the Treatment of Severe Disease Activity Rheumatoid Arthritis [PDF]
目的 对重度疾病活动度类风湿关节炎患者用两种药物治疗方案的治疗效果进行探讨分析。方法 随机抽取本院2015年6月—2016年6月收治的40例重度疾病活动度类风湿关节炎的患者作为研究对象,并将其分为对照组和实验组各20例,对照组采用来氟米特联合甲氨蝶呤进行治疗,实验组在此基础上加入沙利度胺进行治疗,对两组的治疗效果进行对比分析。结果 实验组的治疗效果优于对照组的治疗效果,关节肿胀等不良反应均得到了有效的改善,差异具有统计学意义(P〈0.05)。结论 三种药物联合的治疗效果优于两种药物联合的治疗效果 ...
陈煜
core +1 more source
Research progress on perceived risk of patients with rheumatoid arthritis (类风湿性关节炎患者发病风险感知的研究进展)
Rheumatoid arthritis is an autoimmune disease, and current strategies in the treatment of rheumatoid arthritis (RA) should focus on early identification and diagnosis.
YIN Lingyao (尹凌瑶) +2 more
doaj +1 more source
TIPE2 promote synovial fibroblasts cell apoptosis of adjuvant arthritis rats by up-regulating caspase while down-regulating NF-κB [PDF]
目的:TIPE2能够抑制炎症以及肿瘤的发生发展,并且TIPE2过表达能够促进细胞的凋亡。类风湿关节炎是一种免疫多态性慢性疾病,我们应用类风湿关节炎模型大鼠佐剂型关节炎滑膜成纤维样细胞(fibroblast-likesynoviocytesofratadjuvantarthritis,AA-FLS),通过体外实验分析TIPE2对死亡受体5诱导细胞凋亡的作用探讨TIPE2对佐剂型关节炎发病的影响。 方法:通过RT-PCR、荧光实时定量PCR和Western ...
石春燕
core

