Results 21 to 30 of about 9,466 (165)
在精子发生的不同阶段,睾丸组织特异性基因的按严格的时间、空间特性表达,这些基因在不同的调节因子作用下从多个层次对精子发生过程进行调控,最终形成成熟的精子。本文对生精细胞及非生精细胞中睾丸特异性基因的表达及其调控进行了综述。
余振东 +3 more
doaj
胭脂鱼(Myxocyprinus asiaticus)是亚洲特有的淡水珍稀鱼类,但由于人类活动和生态环境的变化,胭脂鱼数量急剧减少,研究其精子冷冻保存技术及建立精子冷冻保存库,对种质资源的保护和遗传育种具有重要意义。选取健康的雄性胭脂鱼,经人工催产后获得成熟精子,首先对4种精子稀释液种类(D-17、D-15、D-20、人工精浆A)、4种抗冻剂种类(DMSO、GLY、MeOH、PG)及4种DMSO抗冻剂浓度(6%、8%、10%、12%)进行筛选,其次选取筛选后冷冻效果最好的冻精与鲜精做受精实验 ...
丁 小雨 +8 more
doaj +1 more source
Functions of DHP and its nuclear receptor on reproductive neuroendocrine in zebrafish (Danio rerio) [PDF]
本文研究了DHP对野生型和孕酮核受体敲除纯合型两种类型雄性斑马鱼垂体中促性腺激素β亚基基因(fshb和lhb)、脑中多巴胺合成限速酶酪氨酸羟基化酶基因(th2)及多巴胺二型受体基因(drd2a和drd2b)和促性腺激素释放激素基因(gnrh2和gnrh3)mRNA表达的影响。主要研究结果如下: 1.野生型雄性斑马鱼垂体中促性腺激素β亚基基因(fshb和lhb)mRNA表达呈现周日变化趋势,可分为基础表达期、上升表达期和高峰表达期3个期,高峰表达期的mRNA表达量显著高于其它2个期 ...
王翠丽
core
ABSTRACT MCrAlX coatings are widely used as bond coats in thermal barrier coating systems to protect turbine blades from high‐temperature oxidation. However, their oxidation resistance is often restricted by uncontrolled microstructures, surface roughness, and aggregation of reactive elements (REs). In this study, high‐repetition‐rate femtosecond laser
Wei Qian +7 more
wiley +1 more source
Effects of difenoconazole on reproductive ability and lipids metabolism of marine medaka (Oryzias melastigma) [PDF]
苯醚甲环唑(Difenoconazole)是一种三唑类农药,广泛用于水稻、蔬菜等农作物用于防治真菌类感染。苯醚甲环唑对海洋鱼类的毒性报道很少。采用环境浓度的苯醚甲环唑(0、1、10、100和1000ng/L)暴露黑点青鳉180天。探究苯醚甲环唑对黑点青鳉(Oryziasmelastigma)生殖和脂类代谢的影响。 苯醚甲环唑暴露导致雄性黑点青鳉性体比下降,并在1000ng/L组出现差异。苯醚甲环唑处理组的精子数目减少以及精原细胞和精母细胞数量增加。脑中促性腺素释放激素(sGnRH)、促黄体激素(LHβ ...
董晓翠
core
ABSTRACT Mechanoluminescent materials have gained significant attention for their unique capability to convert mechanical stimuli into light without external optical or electrical excitation, holding immense promise for applications in safety monitoring, biomedicine, optical anti‐counterfeiting, and intelligent sensing.
Fanlei Qin +8 more
wiley +1 more source
Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu +12 more
wiley +1 more source
目的筛选与精子发生相关的基因。方法将不同发育阶段的小鼠睾丸组织cDNA探针与Affymetrix全基因组芯片进行杂交,通过杂交信号的比较,筛选出差异表达的基因。利用网络信息资源对该基因进行生物学信息分析。RT-PCR分析该基因在小鼠不同发育阶段睾丸及小鼠不同组织中的表达。结果通过4、91、8、35、54、日龄和6月龄小鼠睾丸的芯片信号比较筛选出一个差异表达杂交点(GenBank登录号:NM-026234),生物信息学分析发现该基因全长3 979 bp,含有1 272 bp的完整ORF ...
唐爱发 +7 more
doaj
Complete androgen insensitivity syndrome, a pedigree gene mutation analysis [PDF]
研究背景 雄激素不敏感综合征(AndrogenInsensitivitySyndrome,AIS),是一种常见的男性假两性畸形。是伴X连锁隐性遗传病。患者染色体核型为46,XY,但其X染色体上的雄激素受体(Androgenreceptor,AR)基因存在缺陷,可致雄激素靶器官上的AR出现缺陷,体内的雄激素不能发挥相应的作用而出现相应的临床症状。此疾病可对患者的生殖能力造成不同程度的影响,还可能引发与性发育异常相关的性心理、性行为的异常,并可能给社会和患者家庭造成难以挽回的损失 ...
杨瑞娟
core
ABSTRACT High‐entropy alloys (HEAs) have emerged as a transformative class of materials distinguished by their complex chemical compositions, unique microstructures, and remarkable mechanical and functional properties. Traditionally, the discovery and optimization of HEAs have relied on conventional methods, including trial‐and‐error experimentation ...
Chrispin Ouko Zamzu +2 more
wiley +1 more source

