Results 31 to 40 of about 19,528 (165)
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Correlation between Chlamydia Pneumoniae IgG Positive in Lung Cancer Patients and Cytokines Related to Radiation-induced Pulmonary Lesion [PDF]
Background and objective There exsits intimate relationship between infection with chlamydia pneumoniae (Cpn) and lung cancer incidence. But few studies have been reported about radiation-induced pulmonary lesion in lung cancer patients infected with Cpn.
Daoan ZHOU +3 more
core
Using genomic data from 285 species across 19 planthopper families, we conducted the first phylogenomic study targeting global planthoppers and inferred their phylogeny with the highest resolution so far. We proposed taxonomic changes including the establishment of a new family Borysthenidae stat. rev. and a new superfamily Meenoploidea superfam.
Junchen Deng +9 more
wiley +1 more source
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
Background – Canine interdigital furunculosis (CIF) is a complex, relapsing inflammatory condition, typically complicated by deep bacterial infections requiring prolonged systemic antibiotics. Hypothesis/Objectives – This split‐body study, where dogs acted as their own control, evaluated whether the adjunctive use of fluorescent light energy (FLE ...
A. Lange +12 more
wiley +1 more source
The Role of SRC-1 in myocardial infarction [PDF]
类固醇激素受体辅激活子(steroidreceptorcoactivator,SRC)作为一类转录协同因子,能够与多种转录因子相互作用并增强其转录活性。SRC-1是SRC家族(SRC-1/NCoA-1、SRC-2/GRIP/TIF2、SRC-3/AIB1/ACTR/pCTP/RAC3/TRAM-1)的一员。已有的研究表明SRC-1在体内具有多种生物学功能,SRC-1可参与乳腺癌、前列腺癌、肝癌等多种癌症的增殖与入侵。SRC-1在脑内突触的可塑性、神经干细胞分化等生理过程具有重要调控作用。此外,SRC ...
占少鹏
core
ABSTRACT Objectives Ultrasound is the first‐line imaging modality of the pelvis in the pediatric and adolescent gynecology (PAG) population. Ultrasound findings in pre‐ and postpubertal PAG patients differ from those in adults. Diagnostic models for adnexal pathology have not been validated in this cohort.
N. Cooper +15 more
wiley +1 more source
目的 回顾性分析肺鳞状细胞癌胞核倍体类型 ,S期细胞比率 ,核体积及形状因子与 5年生存率的关系及四项指标之间的相关性。方法 取我院病理科 1985~ 1990年间肺鳞癌存档蜡块 2 5例 ,5例正常肺组织作对照。应用流式细胞仪测细胞核体积及形状因子。应用图像分析仪测细胞核体积及形状因子。随访 5年。结果 2倍体肺鳞癌5年存活率 85 7% ,异倍体肺鳞癌 5年存活率 11 1%。S期细胞比率大于或等于 2 7%的 5年存活率为 0 % ,S期细胞比率小于 2 7%的 5年存活率 80 ...
闫继东 +4 more
doaj
Recombinant IL-33 prolongs leflunomide-mediated graft survival through reducing Th1-type cytokine IFN-γ and expanding CD4+Foxp3+ regulatory T cells (Treg) in concordant heart transplantation [PDF]
摘要 背景 白细胞介素33是一种非典型的IL-1家族成员。IL-33的给药与Th2型(Th2细胞)的应答促进相关联,其通过促进Th2细胞的活性和Th类型2相关的细胞因子,在体内,特别是以IL-4和IL-5的增殖为代表。最近,在同种异体心脏移植,IL-33显示出其能增加小鼠体内的CD4+Foxp3+调节性T细胞(Treg细胞),并抑制Th1型相关细胞因子IFN-γ的水平。我们采用小鼠到大鼠协调性异种移植模型,我们推测,IL-33和来氟米特可以延长移植物的存活。在这个模型中 ...
代辰
core
Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward +9 more
wiley +1 more source

