Results 21 to 30 of about 12,378 (161)

Dermoscopic evaluation of normal canine skin with a handheld dermoscope

open access: yesVeterinary Dermatology, Volume 36, Issue 5, Page 593-601, October 2025.
Background – Dermoscopy is a noninvasive diagnostic tool that provides a magnified view of skin structures. While dermoscopy is described for certain canine dermatological diseases, large‐scale studies evaluating normal skin are lacking. Hypothesis/Objective – This study aimed to correlate dermoscopic findings with histopathological results in healthy ...
Rachael Loek   +4 more
wiley   +1 more source

200例宫颈细胞学ASC-US诊断的形态学分析

open access: yesZhongguo shiyan zhenduanxue, 2012
目的根据宫颈组织病理诊断结果,分析细胞学诊断为ASC-US的涂片中异常细胞形态变化的特征。方法对细胞学诊断为ASC-US并建议临床活检的200例病例进行组织病理诊断,并回顾性观察、分析细胞学涂片中异常细胞的排列方式、细胞形态、细胞核形态、核染色质的分布等。结果细胞排列方式上,组织学诊断CINⅢ的细胞学涂片中异常细胞片状排列为72.69%,组织学诊断CIN I和CINⅡ的细胞学涂片中异常细胞为单个散在和片状排列平均分布,组织学诊断炎症的涂片中异常细胞单个散在为74.34%。细胞核形态和染色质分布方面 ...
林宁   +7 more
doaj  

Effect of Benzalkonium Chloride on Corneal Epithelial Barrier Function and Possible Mechanisms of Benzalkonium Chloride Inhibiting Corneal Endothelial Gap Junction Intercellular Communication [PDF]

open access: yes, 2015
第一部分:局部应用前列腺素类药物对兔角膜上皮细胞屏障功能的影响 目的:苯扎氯铵(BAK)是滴眼液中最常用的防腐剂之一,大量的临床研究发现,局部长期使用含BAK的眼部制剂会出现很多眼部不适症状。含BAK的前列腺素类药物是治疗开角性青光眼的一线药物,临床上患者往往需要长期使用,易导致眼睛干涩,结膜充血等等,然而其作用机制还不是非常清楚。紧密连接与粘着连接等构成了角膜上皮抵御外界病原微生物入侵的第一道生理屏障,对角膜正常生理功能的维持具有非常重要的作用 ...
张振豪
core  

Phylogenomic insights into the relationship and the evolutionary history of planthoppers (Insecta: Hemiptera: Fulgoromorpha) 基于基因组的系统发育分析为蜡蝉亚目(Fulgoromorpha)的系统发育关系及进化提供新见解

open access: yesSystematic Entomology, Volume 50, Issue 3, Page 495-518, July 2025.
Using genomic data from 285 species across 19 planthopper families, we conducted the first phylogenomic study targeting global planthoppers and inferred their phylogeny with the highest resolution so far. We proposed taxonomic changes including the establishment of a new family Borysthenidae stat. rev. and a new superfamily Meenoploidea superfam.
Junchen Deng   +9 more
wiley   +1 more source

微课在骨髓血细胞形态学教学中的应用

open access: yesZhongguo shiyan zhenduanxue, 2019
骨髓血细胞形态学检查是通过观察骨髓涂片中细胞的形态以及细胞间的比例关系来检查骨髓细胞数量和质的变化,是诊断造血系统疾病最常用的基本方法。但血细胞形态学研究对象为看不见摸不着的血细胞,学生们理解并掌握起来有相当大的难度,给教师和学生提出了一个不小的挑战。
崔红花   +5 more
doaj  

Cytological evaluation, culture and genomics to evaluate the microbiome in healthy rabbit external ear canals

open access: yesVeterinary Dermatology, Volume 35, Issue 5, Page 479-491, October 2024.
Background – Lop‐eared rabbits may be predisposed to otitis externa (OE) as a consequence of their ear conformation. Although otoscopy, otic cytological evaluation, and culture are valuable tools in dogs and cats, published data on rabbits remain lacking. Hypothesis/Objectives – This study aimed to assess the utility of otoscopy and cytological results
Nikoleta Makri   +8 more
wiley   +1 more source

TNF induced RIP3-dependent NADH depletion [PDF]

open access: yes, 2015
肿瘤坏死因子(tumornecrosisfactor,TNF)能诱导L929细胞产生相互作用蛋白3(receptor-interactingprotein3,RIP3)依赖的程序性细胞坏死,并且在该过程中,胞内的线粒体产生的活性氧(reactiveoxygenspecies,ROS)会积聚,同时当RIP3的表达水平敲低时,胞内ROS的积聚也受到了抑制。但是RIP3如何影响ROS的具体机制仍不清楚。 因为ROS的产生主要在线粒体电子传递链上,而还原型辅酶Ⅰ(NADH)和还原型辅酶Ⅱ(NADPH ...
张丽芳
core  

Comparison of selected cytomorphological features of canine pemphigus foliaceus and superficial pyoderma

open access: yesVeterinary Dermatology, Volume 35, Issue 5, Page 524-535, October 2024.
Background – Cytological detection of acantholytic keratinocytes (acantholytic cells [AC]) helps to identify canine pemphigus foliaceus (cPF) yet AC also occurs in superficial pyoderma (SP), the main differential diagnosis. Hypothesis/Objectives – To compare selected cytomorphological features of cPF and SP and to establish cytological diagnostic ...
Tyler S. Spriggs   +3 more
wiley   +1 more source

细胞遗传学联合免疫细胞化学检查在首诊非霍奇金淋巴瘤骨髓侵犯中的应用

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨细胞遗传学和免疫细胞化学检查在非霍奇金淋巴瘤骨髓侵犯(NHL-BMI)中的诊断价值。方法骨髓标本直接涂片Wright-Gimsa染色观察其形态学改变。应用骨髓细胞短期培养法制备染色体标本,以R显带技术进行核型分析。分离骨髓单个核细胞进行免疫细胞化学染色。结果24例淋巴瘤患者,骨髓受累程度各异,淋巴瘤细胞形态多样。CD20和CD79a对B细胞来源、CD3对T细胞来源淋巴瘤有诊断价值。有染色体核型异常的病例占54%(13/24),2例骨髓轻度受累患者检出核型异常。结论综合细胞遗传学 ...
王娜   +4 more
doaj  

Research on the characteristics of 18F-FDG PET/CT in mantle cell lymphoma and the discrimination between cellular morphological variants [PDF]

open access: yes
Objective·To analyze the imaging characteristics and diagnostic value of 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) in mantle cell lymphoma (MCL) and explore its application to distinguishing between classic ...
CAI Mingci   +9 more
core   +1 more source

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