Results 21 to 30 of about 13,612 (158)

微囊藻休眠体复苏机制的研究进展 [PDF]

open access: yes, 2010
围绕我国淡水水体中最常见水华优势种-微囊藻(Microcystis)其休眠体复苏机制国内外主要研究进展进行了介绍及评述。涵盖了微囊藻休眠体越冬过程中细胞形态及结构变化和光合活性及生理代谢变化;介绍了微囊藻休眠体在复苏过程中的主要环境影响因子;并指出了今后新方法 ...
万能, 宋立荣, 汤俊
core  

Phylogenomic insights into the relationship and the evolutionary history of planthoppers (Insecta: Hemiptera: Fulgoromorpha) 基于基因组的系统发育分析为蜡蝉亚目(Fulgoromorpha)的系统发育关系及进化提供新见解

open access: yesSystematic Entomology, Volume 50, Issue 3, Page 495-518, July 2025.
Using genomic data from 285 species across 19 planthopper families, we conducted the first phylogenomic study targeting global planthoppers and inferred their phylogeny with the highest resolution so far. We proposed taxonomic changes including the establishment of a new family Borysthenidae stat. rev. and a new superfamily Meenoploidea superfam.
Junchen Deng   +9 more
wiley   +1 more source

微课在骨髓血细胞形态学教学中的应用

open access: yesZhongguo shiyan zhenduanxue, 2019
骨髓血细胞形态学检查是通过观察骨髓涂片中细胞的形态以及细胞间的比例关系来检查骨髓细胞数量和质的变化,是诊断造血系统疾病最常用的基本方法。但血细胞形态学研究对象为看不见摸不着的血细胞,学生们理解并掌握起来有相当大的难度,给教师和学生提出了一个不小的挑战。
崔红花   +5 more
doaj  

Epithelial-mesenchymal Transition in Renal Cell Carcinoma: The Role of Hepatocyte Nuclear Factor 4α [PDF]

open access: yes, 2013
【背景及目的】 肾癌(renalcellcarcinoma,RCC)是起源于肾小管上皮细胞的恶性肿瘤,占肾脏恶性肿瘤的80%~90%,近年来发病率呈上升趋势。除传统手术治疗外,缺乏其它的有效治疗方法。上皮间质转化(epithelial-mesenchymaltransition,EMT)是上皮细胞在细胞结构、形态、功能等方面获得间质细胞特性的过程,在肿瘤的发生、浸润、转移过程中具有重要作用,核心为上皮标志物E-cadherin表达降低和间质标志物表达增高。肝细胞核因子4α ...
谭伟
core  

Cytological evaluation, culture and genomics to evaluate the microbiome in healthy rabbit external ear canals

open access: yesVeterinary Dermatology, Volume 35, Issue 5, Page 479-491, October 2024.
Background – Lop‐eared rabbits may be predisposed to otitis externa (OE) as a consequence of their ear conformation. Although otoscopy, otic cytological evaluation, and culture are valuable tools in dogs and cats, published data on rabbits remain lacking. Hypothesis/Objectives – This study aimed to assess the utility of otoscopy and cytological results
Nikoleta Makri   +8 more
wiley   +1 more source

细胞形态相似的血液病鉴别诊断分析

open access: yesZhongguo shiyan zhenduanxue, 2008
目的鉴别分析两组疾病包括反应性浆细胞比例增高、多发性骨髓瘤(MM)与原发性巨球蛋白血症,慢性粒细胞白血病(CML)与感染细胞形态学的特征。方法分别对各组病例进行回顾分析血象,骨髓象及特殊染色的特征。结果MM、原发性巨球蛋白血症及浆细胞比例增高骨髓象的浆细胞形态有显著性差异 ...
谢风, 孙晓盈, 王海
doaj  

The Mechanism Study of OVOL2 in Regulation of Epithelial-mesenchymal Transition of Colorectal Carcinoma [PDF]

open access: yes, 2013
实验背景及研究目的:ovo基因编码一组在进化上从果蝇、线虫、斑马鱼到哺乳动物保守的蛋白家族,包括OVOL1、OVOL2及OVOL3,该蛋白家族是含有4个C2H2锌指结构的转录因子。OVOL3只在胚胎早期表达,目前几乎没有相关研究。尽管现在已有许多关于OVOL1、OVOL2在组织发育方面的研究,但它们在肿瘤发生发展过程中的作用还是完全未知。在这篇文章中,我们致力于发现OVOL2与结直肠癌上皮-间质转化过程之间的关系,深入探究其内在分子机理。 实验方法:划痕 ...
陈晨
core  

Comparison of selected cytomorphological features of canine pemphigus foliaceus and superficial pyoderma

open access: yesVeterinary Dermatology, Volume 35, Issue 5, Page 524-535, October 2024.
Background – Cytological detection of acantholytic keratinocytes (acantholytic cells [AC]) helps to identify canine pemphigus foliaceus (cPF) yet AC also occurs in superficial pyoderma (SP), the main differential diagnosis. Hypothesis/Objectives – To compare selected cytomorphological features of cPF and SP and to establish cytological diagnostic ...
Tyler S. Spriggs   +3 more
wiley   +1 more source

Anti-tumor Activities of Marine Natural Product Lagunamide A: A Mechanism Study [PDF]

open access: yes, 2016
本研究以海洋天然产物为对象,系统地分析了lagunamideA及其5个类似物抑制多种肿瘤细胞(A549、HeLa、U2OS、HepG2、BEL-7404、BGC-823、HCT116、MCR-7、HL-60与A375)生长的构效关系,结果表明,C-39位的R构型对活性的保持具有至关重要的作用。在A549细胞中进行的进一步机理研究表明,lagunamideA诱导了caspase依赖性的细胞凋亡。它通过降低膜电位(Δφm),产生大量活性氧(ROS),引起线粒体功能障碍,最终导致细胞死亡 ...
黄伟
core  

A pilot study of antimicrobial effects and ototoxicity of a Norway spruce (Picea abies) resin‐based canine otic rinse product

open access: yesVeterinary Dermatology, Volume 35, Issue 3, Page 325-336, June 2024.
Background – Norway spruce (Picea abies) resin‐based products are used in human medicine. A resin‐based otic rinse also could be useful in supportive care of canine otitis externa (COE), yet information on its antimicrobial effect against canine pathogens or ototoxicity is lacking.
Elina Aimo‐Koivisto   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy