Results 11 to 20 of about 13,994 (168)
Rare Metals, EarlyView.ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT Multi‐element Prussian blue analog (PBA) nanocomposites have attracted wide attention for their superior characteristics to single‐functional nanomaterials in extensive applications of diagnosis and therapy. In this study, a novel hollow nanocomposite was designed and fabricated by embedding S2− and Ag nanoparticles into a NiCuMnFe (PBA).
Tao Ji +7 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang +6 more
wiley +1 more source
Rare Metals, EarlyView.ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang +14 more
wiley +1 more source
Interaction of two-component systems in Thermus thermophilus [PDF]
, 2015 目前，细菌产生了许多机制来对抗抗生素药物的使用，这给细菌性疾病的药物治疗带来了巨大的威胁。细菌感知外界环境压力的其中一个机制就是运用双组分信号转导系统（TCSs）来响应外界刺激。一个TCS一般包含两个组分：组氨酸激酶（HK）和调节应答蛋白（RR）。HK可以感知各种各样的信号，并通过改变它对应的RR的磷酸化水平来调控RR的活性，大部分磷酸化的RR接下来介导转录水平的调控。由于哺乳动物体内不含TCSs，所以TCSs是新的抗生素药物开发的重要靶点。 在一个TCS中 ...
胡晓婕
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Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Organic phosphorus mineralization is a critical process in the phosphorus cycle, governing phosphorus bioavailability for plants. The PhoD gene, which encodes the key enzyme alkaline phosphatase, serves as a valuable biomarker for this process.
Sandhya Mishra +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的根据细菌16S rDNA的高度保守性,设计合成所有细菌的通用引物,建立快速检测细菌的方法。方法应用PCR方法检测细菌16S rDNA基因。同时对白假丝酵母菌、人白细胞DNA和HBV-DNA阳性病人血清同法检测。结果所有检测细菌均出现特异性条带,而白假丝酵母菌、人白细胞DNA和HBV-DNA阳性病人血清阴性。结论该法快速、特异、敏感。一个样品中能同时检测多种细菌,可为实验室初步判断是否存在细菌感染提供客观依据。
詹銮峰, 高鹏
doaj
Zhongguo shiyan zhenduanxue, 2023 目的 了解重症监护病房(ICU)患者感染细菌的分布特征及耐药性。方法 收集2020年至2022年吉林大学中日联谊医院ICU患者分离的1 373株细菌，使用WHONET5.6软件，分析细菌的分布特征及其对抗菌药物的耐药情况。结果 在所分离的1 373株细菌中以革兰阴性菌为主，共827株(60.2%),主要包括肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌及大肠埃希菌。革兰阳性菌546株(39.8%),主要以屎肠球菌及表皮葡萄球菌为主。标本来源以呼吸道(40.9%)、血液(28.3%)和尿(11.8%)占比最高 ...
鄢超 +5 more
doaj
Study on the distribution and diversity of nanoflagellate in the Yangtze estuary and continental shelf of East China Sea [PDF]
, 2015 本研究应用荧光显微技术、荧光标记颗粒示踪法以及Illumina高通量测序技术，分别于2013年春季、2013年夏季和2013年秋季开展了对长江口及东海陆架区微型鞭毛虫的丰度分布、异养细菌的摄食和群落多样性的研究，并初步探讨了影响微型鞭毛虫分布、摄食和群落多样性的因素。主要结果如下： （1）长江口及东海陆架区微型鞭毛虫的丰度变化范围为0.41-7.15×103cellsml-1，微型鞭毛虫丰度的最高值出现在夏季，最低值出现在秋季，表现出明显的季节变化特征 ...
吴林南
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