利用markov模型评价氯吡格雷CYP2C19基因检测的经济学分析 [PDF]
, 2019 目的评价中国进行氯吡格雷CYP2C19基因检测的成本效果分析。方法利用markov模型模拟1万名中国服用氯吡格雷患者的发展过程,从而估计不同治疗方案的累积成本和健康效果。结果与无进行基因检测组相比,利用氯吡格雷CYP2C19基因检测进行指导用药方案,能减少心肌梗死、卒中、出血及死亡的发生率,每增加1个生命年增加花费4097元。结论与无进行基因检测组方案相比,基因检测组具有成本效果,有助于优化治疗方案的选择 ...
于阗, 黄红萍
core
Zhongguo shiyan zhenduanxue, 2021 目的探讨急性冠状动脉综合症(ACS)患者经皮冠状动脉介入治疗(PCI)术前术后血管内皮功能及炎症因子变化的临床意义。方法选取2018年1月至2019年5月125例ACS患者为病例组,63例无ACS病史的健康人群为对照组。检测对照组以及病例组PCI术前、术后1个月、2个月、3个月时的血浆内皮素-1(ET-1)、一氧化氮(NO)、反应性充血后肱动脉内径变化百分率(FMD)、血清白细胞介素-6(IL-6)、IL-8、肿瘤坏死因子-α(TNF-α)。结果术前病例组的血浆ET-1水平高于对照组 ...
尹锐, 贾国渠, 陈巍, 张成伟
doaj
Correlation of Computed Tomography Angiography and Fractional Flow Reserve Features with Symptoms in Patients with Right Coronary Artery Originating from the Left Coronary Sinus [PDF]
Objective: This study aimed to explore the association between the anatomical and hemodynamic characteristics and the clinical symptoms in patients with the origin of the right coronary artery from the left coronary sinus (AORL) using coronary computed ...
Liang MAO +4 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2022 目的 探究血清视黄醇结合蛋白4（RBP4）、细胞间黏附分子（ICAM-1）与冠心病患者经皮冠状动脉介入术（PCI）预后的相关性。方法 选取2017年11-12月500例行PCI术的冠心病患者，随访至2020年12月，根据预后情况分为不良组（n=72）、良好组（n=367）。比较两组术前血清RBP4、ICAM-1水平及其他可能影响因素；Logistic回归分析法分析PCI术预后不良的危险因素；绘制受试者工作曲线（ROC），评价血清RBP4、ICAM-1单独及联合预测冠心病PCI术预后不良的效能。结果 ...
吴忠林, 谢力民
doaj
, 2015 目的探讨临床药师在神经内科的作用。方法临床药师深入临床,在神经内科开展面向医护人员和患者的药学服务,并对部分典型案例进行分析。结果临床药师采用药学问诊,参与制定药物治疗方案,开展药学监护,提供药学信息等方式开展药学服务,发挥了良好的作用。结论临床药师提供多种形式的药学服务,促进了用药安全 ...
孙洲亮, 李彦萍, 林玮玮
core
Curcumin alleviates myocardial inflammatory responses by inhibiting Wnt5a/β-Catennin pathway after coronary microembolization in rats [PDF]
Objective To explore the potential mechanisms of curcumin on myocardial inflammatory responses following coronary microembolization (CME) in rats. Methods Thirty-two SD rats were randomly divided into a sham group, a CME group (model group), a CME ...
LI Lang +4 more
core +1 more source
Predictive value of Clinical Frailty Scale in long term prognosis of patients with acute myocardial infarction after in-hospital cardiac rehabilitation [PDF]
Objective·To investigate the predictive value of the Clinical Frailty Scale (CFS) in the long term outcomes in acute myocardial infarction (AMI) patients who completed in-hospital cardiac rehabilitation (CR).Methods·A total of 501 AMI patients treated in
DANZENG Quyang +7 more
core +1 more source
Growth and Development Trend of Lateral Plaques and Subsequent Plaques in Bifurcated Vessels: A Dynamic Simulation [PDF]
Objective To investigate vascular remodeling and low-density lipoprotein (LDL) deposition, the growth and development trends of lateral branch plaques in bifurcated vessels, and the potential locations of subsequent plaque growth due to the presence of ...
Du, T +7 more
core +1 more source
Development and validation of a multidisciplinary risk assessment scale for immune checkpoint inhibitor-associated myocarditis [PDF]
ObjectiveTo develop a risk assessment scale for immune checkpoint inhibitor (ICI)-associated myocarditis based on multidisciplinary collaboration, and to evaluate its diagnostic performance.
Junbo GE +7 more
core +1 more source
法舒地尔对急性ST段抬高型心肌梗死患者急诊PCI术中无复流现象及内皮细胞功能的影响
Zhongguo shiyan zhenduanxue, 2016 急性ST段抬高型心肌梗死(STEMI)是目前致死的主要原因之一,目前,治疗STEMI的最有效措施为经皮冠状动脉介入治疗(PCI)[1]。开通罪犯血管后,再灌注治疗的效果与受损微血管的再灌注密切相关。开通罪犯血管后,缺血心肌缺乏充分的血液灌注又被称为无复流现象。在急诊PCI术中,无复流现象的发生直接影响手术成功率及患者预后,而目前尚缺乏能够逆转已发生的无复流现象的有效药物[2-4]。近期研究发现 ...
李智博 +4 more
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