Results 71 to 80 of about 17,332 (187)
Multicolor Melting Curve Analysis-based on Detection of Pyrazinamide-Resistant Mycobacterium tuberculosis [PDF]
结核病是由结核分枝杆菌感染人体的慢性传染性疾病。2015年新增患病人数高达1040万,有140万人死于结核病。在众多治疗结核病药物中,吡嗪酰胺是较早发现的一线抗结核药物之一。在酸性环境下,吡嗪酰胺可以抑制巨噬细胞内半休眠结核分枝杆菌。随着吡嗪酰胺广泛使用,耐受吡嗪酰胺的结核病危害面广,因此吡嗪酰胺耐药突变检测的研究急需开展。针对上述问题,本文利用探针熔解曲线分析技术对结核分枝杆菌吡嗪酰胺耐药突变检测展开研究。 第一章绪论,首先简要概述现今世界结核病概况,再介绍耐药结核病诊断和治疗的方法 ...
李梓
core
Accountability in Government Use of AI: Citizen Concerns and Preferences
ABSTRACT Government adoption of AI opens the “pandora's box” of accountability, a core aspect of public value. Despite the centrality of governmental AI accountability, citizens' concerns and preferences in holding governments accountable for AI usage remain poorly understood.
Naikang Feng, Yanto Chandra
wiley +1 more source
Xpert MTB/RIF和荧光定量PCR在痰液标本中快速检测结核分支杆菌的比较
结核病作为全球最严重的公共卫生威胁,世界卫生组织发布的2015年全球结核病报告显示结核菌的感染率首次逼近艾滋病,2014年共有960万新发结核病病例,150万人死于结核病,其中40万人同时感染了艾滋病毒。我国2014年新发结核病病例93万,仅次于印度与印度尼西亚而位居全球第三[1]。结核病防控的一个重要方面是快速 ...
杜鹏 +6 more
doaj
Expressions of Cyr61 and WISP-3 in Non-small Cell Lung Cancer and Its Clinical Significance [PDF]
Background and objective Cysteine-rich protein 61 (Cyr61) plays a role as a tumor suppressor in non-small cell lung cancer (NSCLC). Cyr61 and WISP-3 have a very significant sequence homology, belonging to the same CCN gene family.
Chunwei ZHANG +3 more
core
Emotion and the Advocacy Coalition Framework: An Affective Dynamics Perspective
ABSTRACT Despite extensive evidence that emotion and cognition are deeply intertwined, the Advocacy Coalition Framework (ACF) lacks an analytically independent emotional mechanism in its causal architecture—an omission that may be particularly consequential in policy subsystems structured around morally charged, identity‐laden policy disputes.
Moshe Maor
wiley +1 more source
目的探讨实时荧光定量聚合酶链反应技术(RT-PCR)对结核性脑膜炎的诊断价值。方法分别采用涂片法、RT-PCR法对结核性脑膜炎、疑似结核性脑膜炎以及非结核性脑膜炎患者的脑脊液标本进行检测,并对检测结果进行比较分析。结果涂片法共检出10例阳性,其中结核性脑膜炎7例(70.00%),疑似结核性脑膜炎3例(30.00%);RT-PCR法共检出46例阳性,其中结核性脑膜炎31例(67.39%),疑似结核性脑膜炎15例(32.61%)。对结核性脑膜炎患者检测,涂片法阳性率(12.28%)低于RT-PCR法阳性率 ...
杨柳 +7 more
doaj
Study on the diagnostic value of macrophage migration inhibitory factor in neurosyphilis [PDF]
目的: 神经梅毒诊断依赖于实验室检查结果,脑脊液(cerebrospinalfluidrapid,CSF)快速血浆反应素环状卡片试验(rapidplasmareagintest,RPR)常作为神经梅毒的确诊指标,但脑脊液RPR的灵敏度低,易造成漏诊;即使结合脑脊液的其他参数(蛋白和白细胞等),也可能造成神经梅毒的漏诊。巨噬细胞移动抑制因子(macrophagemigrationinhibitoryfactor,MIF)作为一种炎症因子已广泛应用于神经系统疾病的诊断 ...
张亚锋
core
Use of a Cytobrush for Sampling the Ear Canal of Dogs With Otitis Externa
Cytological examination of the ear canal is essential for evaluating dogs with otitis externa (OE). The conventional sampling method uses a swab. However, the cytobrush (gynaecological cervical brush), already used for cytological collection from other anatomical sites, has not been adequately investigated for this purpose in dogs with OE.
Nicoly Radaeli Atanasio +3 more
wiley +1 more source
结核病是严重危及全球的公共卫生问题之一,高耐药性结核病的流行,成为结核病诊断和治疗的难点。结核菌的培养和药敏结果,在结核病的防治中起着重要作用[1]。目前公认的结核分枝杆菌培养方法有两种,一是液体培养基快速检测法,其营养成分高,培养速度快,一般仅需10-20天 ...
赵大力, 韩中波, 周亚丽
doaj
Diagnosis and Treatment of Tracheal or Bronchuotracheal Adenoid Cystic Carcinoma [PDF]
Background and objective Adenoid cystic carcinoma is primary bronchopulmonary carcinoma with low malignancy, and 43 patients treated in the past 50 years in our hospital were retrospectively studied.
Daping YU +5 more
core

