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基于“形气神”理论探析缺血性脑卒中的神经元铁死亡机制的临床内涵

Medical Research and Practice
缺血性脑卒中(IS)因其高致残率、复发率及致死率,临床治疗亟需突破再灌注后神经损伤的干预瓶颈。铁死亡作为由脂质过氧化与活性氧异常蓄积驱动的新型细胞死亡方式,已被证实参与脑缺血再灌注损伤的病理进程。中医学认为,IS属“中风”范畴,病机关键为风火痰瘀痹阻脑络,导致形、气、神三者失和,进而引发肢体功能障碍与神经损伤。本文基于中医“形神气一体”理论,探讨IS病程中形气神受损与神经元铁死亡的内在关联,揭示中医药通过调和形、气、神以调控铁死亡通路的潜在靶点。
盼盼 吴, 涛 郭
semanticscholar   +1 more source

输液及再灌注治疗中伴出血性转化的缺血性脑卒中不良结局因素分析

Themed collection of papers from Foreign international scientific conference «Joint innovation - joint development». by HNRI «National development» in cooperation with PS of UA. December 2025. – Harbin (China)
Analyzing the factors associated with adverse outcomes in hemorrhagic transformation of ischemic strokes, certain patterns were identified during infusion and reperfusion therapy.
O. V. Zolotarev   +1 more
semanticscholar   +1 more source

非优势大脑半球缺血性脑卒中患者存在的急性期脑功能连接改变:基于rs-fMRI技术

, 2021
高静纯   +7 more
semanticscholar   +1 more source

脑-肠轴在缺血性脑卒中及其并发症中的机制探索与应用展望

Scientia Sinica Vitae, 2022
Kaiyu Xu   +4 more
semanticscholar   +1 more source

中国急性缺血性脑卒中诊治指南2010

, 2010
中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组
semanticscholar   +1 more source

中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2010

, 2010
中华医学会神经病学分会脑血管病学组缺血性脑卒中二级预防指南撰写组
semanticscholar   +1 more source

老年急性缺血性脑卒中患者血清miR-150-5p及miR-148b-3p的表达及其临床意义

, 2020
郝玉青   +9 more
semanticscholar   +1 more source

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