Zhongshan Daxue xuebao. Yixue kexue ban, 2004 ［目的 l 探讨铝佐剂Al3,2及其C端亚单位肤Al3J6 -•2疫苗接种大鼠能否产生特异性抗Al3,2抗体。【方法】24只SD大鼠随机分为Al3., 肤疫苗、Al3,• -•2肤疫苗和对照组，每组8只。将Al3,2肤疫苗及Al3J• _,, 与七聚赖氨酸耦联制成的亚单位疫苗分别接种千SD大鼠， 对照组用等体积PBS加铝佐剂。 用间接ELISA法检测 大鼠血清和脑匀浆上清液中特异性抗体的滴度；用Morris水迷宫测试大鼠的行为学变化；用HE染色观察大鼠 的脑、肝、脾和肾组织学变化 ...
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