Results 11 to 20 of about 19,620 (155)
International Journal of Immunogenetics, Volume 50, Issue 6, Page 299-305, December 2023., 2023 Abstract Hepatitis B virus (HBV) is responsible for various liver diseases, such as chronic hepatitis B (CHB), liver fibrosis, liver cirrhosis (LC) and hepatocellular carcinoma (HCC), which pose a significant threat to human health. An ineffective immune response to HBV can result in viral chronicity.
Hai Cheng +3 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023 Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee +7 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022 Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An +7 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022 Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya +2 more
wiley +1 more source
The psychometric properties of the quick inventory of depressive symptomatology-self-report (QIDS-SR) in patients with HBV-related liver disease [PDF]
, 2017 Background: Comorbid depression in Hepatitis B virus (HBV) is common. Developing accurate and time efficient tools to measure depressive symptoms in HBV is important for research and clinical practice in China.
Duan, Zhong-ping +7 more
core +2 more sources
, 1993 Relationship between ethanol drinking and organs injury was reviewed and special emphasis was put on alcoholic liver disease. Consumption of alcoholic beverage expressed as ethanol per capita of adult in Japan increased 2.1 times in these 25 years and it
Endo, Hiroshi +4 more
core +1 more source
, 1997 肝炎はよく見られる難病の一種であり，その病原としてウイルス，薬物，アルコールおよび自己免疫反応などが挙げられる。そのうち，ウイルス性肝炎（とくにB型とC型肝炎ウイルスの感染によるもの）が多く、これらの持続感染により慢性化となり，厳重の場合は肝硬変，肝癌まで至る。肝炎の慢性化進展における詳細なメカニズムについてはまだ解明されていないが，免疫学的機序の関与が多く報告されている。例えば，B型肝炎はウイルス感染だけでは発症せず，T細胞を介した細胞性免疫反応，すなわち，B型肝炎ウイルス(HBV)-encoded ...
徐 強
core +1 more source
Cガタ マンセイ カンエン ノ チリョウ センリャク [PDF]
, 2007 Ｃ型肝炎ウイルス（HCV）感染症は、自然治癒が稀で、自覚症状に乏しく、長年の経過で慢性肝炎から肝硬変や肝臓癌へ進展する。現在、わが国には、HCV 感染者が約200万人いると推定されており、Ｃ型慢性肝炎対策は急務とされている。Ｃ型肝炎治療薬として、インターフェロン（IFN）は1992年２月から保険診療が可能となり、治療効果向上のため、多くの投与法の変遷を遂げてきた。2004年12月より、Pegylated IFN とリバビリンの併用療法が保険診療に加わり ...
三沢 慶子 +3 more
core +1 more source
Mathematical analysis of pathogenesis of viral hepatitis. [PDF]
, 2000 Simple mathematical models are considered to explain the pathogenesis of viral hepatitis. Dynamics of populations of liver cells and two virus strains are analyzed qualitatively.
Kajiwara, Tsuyoshi, Sasaki, Toru
core +1 more source