Results 11 to 20 of about 5,876 (110)
Journal of Diabetes, Volume 15, Issue 1, Page 27-35, January 2023., 2023 Highlights This study constructed the first 5‐year all‐cause mortality risk prediction model for patients with type 2 diabetes mellitus in south China. This well‐performing model, using highly accessible predictors collected in routine clinical settings, provides a powerful tool for clinicians to identify high‐risk diabetic patients.
Jiying Qi +10 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022 Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya +2 more
wiley +1 more source
Chinese Clinical Named Entity Recognition with ALBERT and MHA Mechanism
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Traditional clinical named entity recognition methods fail to balance the effectiveness of feature extraction of unstructured text and the complexity of neural network models. We propose a model based on ALBERT and a multihead attention (MHA) mechanism to solve this problem.
Dongmei Li +4 more
wiley +1 more source
Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion
Scientific Programming, Volume 2021, Issue 1, 2021., 2021 The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang +5 more
wiley +1 more source
染色质解旋酶DNA结合蛋白7表达与肝癌临床病理特征及预后的关系
Zhongguo shiyan zhenduanxue, 2017 目的通过研究肝癌组织内染色质解旋酶DNA结合蛋白7（CHD7）的表达及其与肝癌患者临床病理特征及预后的关系,探讨CHD7作为肝癌预后预测指标的可行性。方法将286例肝切除术后病理确诊为肝细胞肝癌的标本制作成组织芯片。采用免疫组化法检测肝癌及癌旁肝组织中CHD7的表达水平,分析其与肝癌患者临床病理特征及预后之间的关系。结果免疫组化结果显示CHD7在肝癌组织中表达明显高于对应的癌旁肝组织。CHD7高表达与肿瘤数目、肿瘤包膜完整性、肿瘤血管侵犯、TNM分期及BCLC分期密切相关 ...
陈颖 +6 more
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Zhongguo shiyan zhenduanxue, 2003 目的 研究外周血肝癌发生相关甲胎蛋白 （AFP）基因在肝癌早期诊断和鉴别诊断中的价值。方法 :从肝癌组织和肝病患者外周血中制备总RNA ,经随机引物和逆转录酶作用合成cDNA ,再以逆转录巢式聚合酶链反应 （RT -PCR）扩增AFP基因 ,并分析其临床价值。结果 RT -巢式PCR扩增的AFP基因片段为 15 9bp ,与原设计一致 ;在 2 0份肝癌及其癌周和远癌组织中 ,AFP基因阳性率分别为 10 0 %、6 5 %和 0 % ;肝癌患者外周血AFP基因检出率为 5 3.7% ,明显高于肝硬化 ...
杨大明 +5 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2020 【目的】探讨多巴胺受体4（DRD4）在肝细胞癌组织以及癌旁组织的表达，分析其表达情况与肝癌术后患者预后相关临床病理因素的关系和预后意义；探讨DRD4 激动剂PD-168077 以及阻滞剂L-745870 对肝癌细胞增殖、迁移及侵袭的影响，并分析其可能的机制。【方法】通过免疫组化以及实时定量PCR（qPCR）技术检测肝 癌以及癌旁组织 DRD4 蛋白和 mRNA 表达情况，并分析 DRD4 表达的预后意义；采用 Cell Counting Kit 8（CCK8） 和 Transwell 实验检测 ...
严俨 +7 more
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