Results 11 to 20 of about 6,038 (111)

Developing a prediction model for all‐cause mortality risk among patients with type 2 diabetes mellitus in Shanghai, China 中国上海地区建立的2型糖尿病患者全因死亡风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 1, Page 27-35, January 2023., 2023
Highlights This study constructed the first 5‐year all‐cause mortality risk prediction model for patients with type 2 diabetes mellitus in south China. This well‐performing model, using highly accessible predictors collected in routine clinical settings, provides a powerful tool for clinicians to identify high‐risk diabetic patients.
Jiying Qi   +10 more
wiley   +1 more source

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes 一种新兴的1型糖尿病治疗策略:靶向胰腺β细胞中的PI3K/Akt信号通路以增强其存活和功能

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya   +2 more
wiley   +1 more source

Chinese Clinical Named Entity Recognition with ALBERT and MHA Mechanism

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Traditional clinical named entity recognition methods fail to balance the effectiveness of feature extraction of unstructured text and the complexity of neural network models. We propose a model based on ALBERT and a multihead attention (MHA) mechanism to solve this problem.
Dongmei Li   +4 more
wiley   +1 more source

Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion

open access: yesScientific Programming, Volume 2021, Issue 1, 2021., 2021
The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang   +5 more
wiley   +1 more source

Abstracts

open access: yes, 2022
Cancer Science, Volume 113, Issue S1, Page 1-1874, February 2022.
wiley   +1 more source

Comparison of ultrasound with computed tomography and whole‐body diffusion‐weighted MRI in prediction of surgical outcome using ESMO‐ESGO criteria in patients with tubo‐ovarian carcinoma: prospective ISAAC study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 2, Page 207-219, February 2026.
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova   +26 more
wiley   +1 more source

膜型基质金属蛋白酶一1 在肝癌组织中的表达及意义

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2005
【目的】比较膜型基质金属蛋白酶-1(membrane type-1 matrix metalloproteinase,MT1-MMP)在大肝癌(瘤体直径>3cm)及小肝癌(单肿瘤结节且瘤体直径≤3cm)组织中的表达差异,并探讨其在肝癌肿瘤细胞浸润、转移过程中的作用。【方法】应用半定量RT-PCR方法检测MT1-MMP mRNA在22例大肝癌及12例小肝癌组织中的表达;应用免疫组化方法检测MT1-MMP蛋白在53例大肝癌及40例小肝癌组织中的表达,并分析MT1-MMP蛋白表达水平与肝癌浸润、转移之间的关系。
何萍   +4 more
doaj  

Abstracts

open access: yes
Cancer Science, Volume 116, Issue S1, Page 1-1975, January 2025.
wiley   +2 more sources

人肝癌组织和外周血中甲胎蛋白基因片段扩增及临床应用

open access: yesZhongguo shiyan zhenduanxue, 2003
目的 研究外周血肝癌发生相关甲胎蛋白 (AFP)基因在肝癌早期诊断和鉴别诊断中的价值。方法 :从肝癌组织和肝病患者外周血中制备总RNA ,经随机引物和逆转录酶作用合成cDNA ,再以逆转录巢式聚合酶链反应 (RT -PCR)扩增AFP基因 ,并分析其临床价值。结果 RT -巢式PCR扩增的AFP基因片段为 15 9bp ,与原设计一致 ;在 2 0份肝癌及其癌周和远癌组织中 ,AFP基因阳性率分别为 10 0 %、6 5 %和 0 % ;肝癌患者外周血AFP基因检出率为 5 3.7% ,明显高于肝硬化 ...
杨大明   +5 more
doaj  

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