Results 11 to 20 of about 12,712 (160)

Developing a prediction model for all‐cause mortality risk among patients with type 2 diabetes mellitus in Shanghai, China 中国上海地区建立的2型糖尿病患者全因死亡风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 1, Page 27-35, January 2023., 2023
Highlights This study constructed the first 5‐year all‐cause mortality risk prediction model for patients with type 2 diabetes mellitus in south China. This well‐performing model, using highly accessible predictors collected in routine clinical settings, provides a powerful tool for clinicians to identify high‐risk diabetic patients.
Jiying Qi   +10 more
wiley   +1 more source

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes 一种新兴的1型糖尿病治疗策略:靶向胰腺β细胞中的PI3K/Akt信号通路以增强其存活和功能

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya   +2 more
wiley   +1 more source

Chinese Clinical Named Entity Recognition with ALBERT and MHA Mechanism

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Traditional clinical named entity recognition methods fail to balance the effectiveness of feature extraction of unstructured text and the complexity of neural network models. We propose a model based on ALBERT and a multihead attention (MHA) mechanism to solve this problem.
Dongmei Li   +4 more
wiley   +1 more source

Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion

open access: yesScientific Programming, Volume 2021, Issue 1, 2021., 2021
The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang   +5 more
wiley   +1 more source

Abstracts

open access: yes, 2022
Cancer Science, Volume 113, Issue S1, Page 1-1874, February 2022.
wiley   +1 more source

肝硬化结节与肝癌的关系

open access: yesZhongguo shiyan zhenduanxue, 1998
肝硬化结节与肝癌的关系沈锋丛文铭吴孟超多项统计资料和临床观察的结果已肯定,随着肝硬化病程的进展,除了食道胃底静脉出血、肝功能失代偿外,肝癌是主要的肝硬化致死性因素,肝炎→肝硬化→肝癌被认为是肝癌发生的“三部曲”。日本肝癌研究组报道了一组4354例肝癌...
沈锋, 丛文铭, 吴孟超
doaj  

The metabolism of endogenous lipids in hepatocellular carcinoma [PDF]

open access: yes, 2015
研究背景:原发性肝细胞癌(以下简称原发性肝癌)是肝脏主要的恶性肿瘤,由于其起病隐匿,进展迅速,确诊时大多数患者已达到晚期或发生远处转移,治疗困难,因此提高原发性肝癌的诊断及愈后至关重要。有研究证明内源性大麻素系统可以通过多条通路产生抗肿瘤作用,但其与原发性肝癌发生发展的关系及治疗作用尚未完全阐明。 目的:本课题通过相关实验技术研究内源性大麻素系统与原发性肝癌之间的内在联系,探讨相关机制,以期发现原发性肝癌发生早期的生物标志物;并通过调控内源性脂质,探讨有效治疗原发性肝癌的特异性靶标。 方法 ...
李蕾
core  

甲胎蛋白与癌胚抗原在原发性肝癌与转移性肝癌鉴别诊断中的意义分析

open access: yesZhongguo shiyan zhenduanxue, 2013
肝癌是常见的消化系统恶性肿瘤之一,严重危险到患者生命安全。根据肝癌的发生情况可把肝癌原发性肝癌和转移性肝癌。肝癌的早期诊断和早期给予有效治疗,有利于提高患者预后[1,2]。在对肝癌的诊断中,除了影像学检查外,还有相关因子的检测有助于诊断。本文观察甲胎蛋白与癌胚抗原在原发性肝癌与转移性肝癌鉴别诊断中的意义。现报告如下。1材料与方法 1.1一般资料选择我院2009年8月至2013年8期间收治的肝癌患者89例 ...
刘英平, 潘在兴
doaj  

Effects of Ciji Hua’ai Baosheng Decoction on Hematopoiesis & Tumor Cells Apoptosis Related Factors of Tumor-bearing Chenmotherapy Mice with H22 Hepatoma Carcinoma Cells [PDF]

open access: yes, 2015
目的:研究并证实慈济化癌保生汤(CijiHua’aiBaoshengDecoction,CHBD)对肝癌化疗后机体整体机能的改善作用,明确慈济化癌保生汤对肝癌化疗后机体血细胞的保护作用、造血相关因子的生成作用、促肿瘤细胞凋亡作用,为慈济化癌保生汤在临床的应用提供科学依据。 研究方法:培养昆明(KM)小鼠肝癌H22细胞,稀释为2×107/ml,接种于60只小鼠右前腋下,常规饲养7天后,全部形成皮下移植瘤,以环磷酰胺(CyclophosphamideTabletsandInjections,CTX ...
程尧
core  

Home - About - Disclaimer - Privacy