肝癌细胞株SMMC-7721中CD147和MMP-9的表达及意义
Zhongguo shiyan zhenduanxue, 2008 目的研究肝癌细胞系SMMC-7721中CD147与基质金属蛋白酶-9（MMP-9）的表达及意义。方法用流式细胞仪检测正常肝细胞L-02与肝癌细胞SMMC-7221中CD147的表达;用免疫组化法检测两种细胞产生的MMP-9的表达。结果正常肝细胞L-02中CD147表达阴性,SMMC-7721中CD147表达呈强阳性（阳性率为98.1%）;MMP-9在正常肝细胞及肝癌细胞中均有表达,但在肝癌细胞中表达明显增高。结论肝癌细胞系SMMC-7721中CD147与MMP-9表达明显增高,与肝癌的侵袭转移潜能有关。
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Zhongshan Daxue xuebao. Yixue kexue ban, 1992 1980～1990年,作者收治原发性肝癌660例,手术切除124例(18.8％)。术后肝内复发者32例(肝内复发率25.8％),2 年以内复发者占93.8％。93.7％合并肝硬化,15.5％并发门脉高压症。复发肝癌中4例(3.2％,4/124)行再切除,术后生存平均26.8月;22例行B超引导肝癌复发灶无水酒精注射术,术后8例死亡,平均生存8.5月;10例行肝动脉栓塞化疗或肝动脉结扎及插管化疗,术后生存平均16.8月,对照组仅4.5月。复发癌再次外科治疗以再切除术为首选(术后生存26.8～42.6月 ...
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