Zhongshan Daxue xuebao. Yixue kexue ban, 1992 采用单个细胞水平细胞毒方法研究比较了正常人外周血自然杀伤(NK)细胞对不同靶细胞结合与杀伤活性的差别。发现NK细胞对人胚胎成纤维细胞和低分化鼻咽癌(CNE-2)细胞的结合率明显高于对人成骨肉瘤细胞(OS-732)和PLC/PRF/5人肝癌细胞,结合并杀伤新鲜切除人肝癌细胞,而对同一病人的癌周肝细胞则无作用;在同一株CNE-2细胞中,NK多选择性地与核浆比例大的靶细胞结合。以上结果说明NK细胞在发挥自然细胞毒过程中具有一定的选择性,选择性地结合并杀伤分化差或幼稚的靶细胞。
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辐射对肝癌细胞HepG2多药耐药基因MDR1表达影响的实验研究
Zhongguo shiyan zhenduanxue, 2006 目的辐射对肝癌细胞多药耐药性的影响。方法取肝癌细胞株HepG2及HepG2/ADM分别进行X线照射（10Gy）,于照射前后分别采用流式细胞仪检测各组细胞表面Pgp变化,采用RT-PCR法检测MDR1表达变化。结果照射前后HepG2细胞表面P-gp阳性表达率分别为:（11.3±1.2）%（、27.4±3.9）%;HepG2/ADM组为:（45.5±5.1）%,（48.1±6.1）%。HepG2组P-gp在细胞膜上的表达较照射前后差异有显著性意义 ...
王宁, 李玉, 刘洁
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[NDRG2 inhibits tumorigenesis of hepatocellular carcinoma by regulating metabolism of phospholipids and triglyceride: a metabonomic analysis]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2022 Wang J +8 more
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Construction of web-based prediction nomogram models for cancer-specific survival in patients at stage IV of hepatocellular carcinoma depending on SEER database. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Zhan G, Cao P, Peng H.
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Influence of different region of interest sizes on CT-based radiomics model for microvascular invasion prediction in hepatocellular carcinoma. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2022 Zhao H +5 more
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[Angio-associated migratory cell protein is highly expressed in hepatocellular carcinoma and promotes tumor cell invasion and metastasis]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi C, Yin G, Cheng X, Jiang Y.
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乙肝病毒X蛋白对肝癌细胞组蛋白H3K4甲基化修饰的影响及机制
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 探讨乙肝病毒X蛋白(HBx)与肝癌细胞组蛋白H3K4位点甲基化修饰的关系及其可能的机制?【方法】构建稳定表达HBx基因的HepG2-hbx及载体对照细胞系HepG2-vc,同时培养用于阳性对照的肝癌细胞系HepG2.2.15及阴性对照细胞系HepG2;用酶标法检测各组细胞组蛋白H3K4位点甲基转移酶活性,比较HBx对H3K4位点甲基转移酶活性的影响;qRT-PCR检测各组细胞中H3K4位点特异性甲基转移酶SMYD3 ( SET and MYND domain containing3 ...
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[Research Advances in the Roles of High-Altitude Hypoxic Stress in Hepatocellular Carcinoma]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanLiang Y +7 more
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[Research progress on ferroptosis regulation in tumor immunity of hepatocellular carcinoma]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanMo Y, Zou Z, Chen E.
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[Overexpression of parathyroid hormone-like hormone facilitates hepatocellular carcinoma progression and correlates with adverse outcomes]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoMiao X +9 more
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