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Effect and Mechanism of Soluble Dietary Fiber from Corn Bran on Loperamide-induced Constipation in Mice [PDF]
This study was performed to elucidate effects of corn bran soluble dietary fibers (CSDF) on loperamide-induced constipation and changes in intestinal flora in mice. Sixty male BALB/c mice were randomly divided into a normal group, a model group, CSDF low,
Caixia JIANG +4 more
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利用Illumina测序技术分析圈养成年滇金丝猴肠道菌群多样性
野生动物学报, 2019 选取中国科学院昆明灵长类研究中心的4只成年健康滇金丝猴和1只成年亚健康滇金丝猴，基于高通量测序技术分析其肠道细菌群落的组成和多样性，探讨健康状况对成年滇金丝猴肠道微生物的影响，揭示其肠道微生态特征。结果表明：在门水平上，健康滇金丝猴的主要菌群有厚壁菌门（Firmicutes，78.41%）、拟杆菌门（Bacteroidetes，18.97%）；在属水平上，主要菌群有瘤胃球菌属（Ruminococcus，6.29%）、未分类的毛螺菌科（unidentified Lachnospiraceae，420 ...
金洁 1 张飞燕 1 谢丽分 1 刘超 1 张庆宇 1 邬继文 1 吕龙宝 1 +1 more
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Regulatory Effect of Fermented Oat on Immune Cytokines and Gut Health in Healthy Adults [PDF]
Objective: To investigate the regulatory effect of fermented oat on immunity and gut health in healthy adults in order to provide scientific evidence supporting dietary recommendations to enhance immune function and gut health.
YAN Qinyu, XIA Hui, XIA Jiayue, YU Junhui, WANG Xin, XIANG Xuesong, YANG Weiwei, FENG Meiyuan, SUN Guiju
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Zhongguo shiyan zhenduanxue, 2011 目的定量检测脓毒症大鼠肠道主要菌群的变化情况,同时找出引起脓毒症大鼠患病甚至死亡的主要致病菌。方法采用盲肠结扎穿孔法（CLP）制作大鼠脓毒症模型,取腹水进行细菌培养和菌种鉴定;同时取结肠内容物提取DNA,使用荧光定量PCR法对肠道内5种细菌进行定量。结果与对照组相比模型组大鼠肠道内双歧杆菌、乳杆菌数量明显减少,而大肠埃希菌的数量则有所增加。同时大肠埃希菌在腹水中大量繁殖。结论肠道中益生菌数量减少和条件致病菌的大量繁殖是导致脓毒症大鼠发病和死亡的微生态学因素。
刘大全 +4 more
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Research advances Progress in the pathogenesis of IgA nephropathy [PDF]
As the most common primary glomerular disease in the world, IgA nephropathy (IgAN) is one of the major causes of end-stage renal disease (ESRD). With the in-depth studies of IgAN, researchers have gradually clarified the important roles of galactose ...
Bing Li +4 more
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Progress of olfactory changes in metabolic diseases and the mechanisms [PDF]
Metabolic disorders, characterized by a complex pathogenesis, are experiencing a rising prevalence globally and a trend toward younger populations, making them a significant public health concern.
LI Huating, WU Qian
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野生动物学报, 2012 寄生菌是动物体非特异性免疫的重要组成部分,体表或体内的微生态系统对于牵制或抑制外来有害病原体起到重要作用。生殖道内的寄生菌对于维持生殖道内的稳态起着重要作用。2011年年初在对北京动物园2只健康的雌性大熊猫"萌萌"和"瑛华"进行人工授精过程中,抽取阴道深部（约15 cm处）分泌物,于有氧和无氧两种条件下,进行了细菌培养。2只大熊猫的培养结果完全相同。均主要有三株细菌,利用API鉴定试剂条鉴定的结果是L群链球菌、溶血性大肠杆菌和乳杆菌。对数量较多的链球菌和溶血性大肠杆菌进行了药物敏感试验以及16s ...
刘燕 +7 more
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Simulated Digestion of Polygonatum sibiricum Extract in Vitro and Its Effect on Intestinal Flora [PDF]
Objective: To explore the changes of active components in Polygonatum sibiricum extract and its regulation on intestinal flora by in vitro simulated digestion combined with 16S rDNA high-throughput sequencing technology. Methods: P. sibiricum extract was
Aixin CHANG +4 more
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野生动物学报为了掌握鄱阳湖周边农田生境中越冬白鹤（Leucogeranus leucogeranus）和鸿雁（Anser cygnoides）的肠道微生物多样性，利用高通量测序技术，对来自五星垦殖场和康山垦殖场的200份白鹤、鸿雁粪便样品进行检测。结果表明：厚壁菌门（Firmicutes）是白鹤肠道菌群的绝对优势菌门，厚壁菌门和变形菌门（Proteobacteria）是鸿雁肠道菌群的绝对优势菌门，白鹤肠道菌群多样性低于鸿雁，且二者肠道菌群结构存在显著差异。白鹤和鸿雁共携带184种病原菌，包括动物病原菌 ...
张阳 +4 more
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Zhongguo cuzhong zazhi目的 通过建立急性轻型缺血性卒中（mild ischemic stroke，MIS）患者队列，探索肠道微生物群与MIS患者临床功能预后间的关系，寻找不良功能预后的干预靶点。 方法 前瞻性连续纳入2018年9月—2023年3月于南方医科大学南方医院神经内科住院的卒中事件后7 d内入院的急性MIS（入院NIHSS评分≤5分）患者，根据90 d随访评估结果，分为预后良好（mRS评分≤2分）组及预后不良（mRS评分＞2分）组。入院后24 h内收集入组患者粪便样本 ...
任悦冉，梁京儒，郑逸锋，尹恝 (REN Yueran, LIANG Jingru, ZHENG Yifeng, YIN Jia )
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