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野生动物学报为探究食物主要营养成分对花鼠（Tamias sibiricus）肠道菌群结构的影响，以人工饲料饲喂花鼠，以野外自由取食为对照，通过粪便采样，以16S rRNA高通量测序分析花鼠肠道菌群组成。依据食物来源和饲料中脂肪、淀粉含量的不同，将被饲喂的花鼠分为野外组、脂肪组、淀粉组和饲料组。结果显示：不同饲喂条件下，花鼠肠道菌群的优势菌门均为厚壁菌门（Firmicutes）、拟杆菌门（Bacteroidetes）和变形菌门（Proteobacteria ...
朱紫薇 +5 more
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Research Progress on the Correlation between Different Dietary Patterns and Hyperuricemia Mediated by Intestinal Flora [PDF]
Hyperuricemia (HUA) is a purine metabolism disorder caused by the imbalance between uric acid production and excretion, which, when severe, can lead to gout and renal function damage.
LU Han, ZHAO Kexin, XUE Yuling, MA Xinying, WANG Shijie
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Zhongshan Daxue xuebao. Yixue kexue ban多囊卵巢综合征（PCOS）是育龄期女性最常见的内分泌疾病之一，以排卵功能障碍、高雄激素血症及卵巢多囊样改变为核心特征，是导致女性不孕的主要原因，全球患病率达6%~20%。由于PCOS的复杂性和异质性，其发病机制目前尚未完全阐明，现有证据证明肠道菌群失调和胆汁酸代谢异常可能参与PCOS的发病过程。PCOS患者肠道菌群a多样性下降，产丁酸盐菌减少和拟杆菌属等有害菌增殖，导致肠道屏障受损和慢性炎症，并通过短链脂肪酸与性激素代谢失调加剧胰岛素抵抗和高雄激素血症。PCOS患者胆汁酸代谢异常表现为总胆汁酸水平升高 ...
林康毅, 鄞国书
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野生动物学报, 2020 利用高通量测序方法对虎纹蛙前肠、中肠和后肠微生物结构和功能进行分析。结果表明，虎纹蛙（Rana rugulosa）肠道核心菌群是厚壁菌门（Firmicutes）、变形菌门（Proteobacteria）、拟杆菌门（Bacteroidetes）、梭杆菌门（Fusobacteria）和放线菌门（Actinobacteria）。Romboutsia属、鲸杆菌属（Cetobacterium）、叶杆菌属（Phyllobacterium）是绝对优势菌属。肠道中存在弧菌（Vibro）、邻单胞菌（Plesiomonas）
刘文舒 +5 more
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Research progress in mechanisms of gut microbiota in diabetic cognitive impairment and its targeted intervention [PDF]
Diabetes mellitus type 2 might cause mild cognitive impairment in its advanced stages, potentially progressing to dementia. Diabetic cognitive impairment (DCI) stands as a chronic complication of diabetes mellitus, with its underlying pathogenesis still ...
AN Yu +4 more
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野生动物学报, 2020 高原鼠兔和高原鼢鼠是青藏高原的两种优势小型哺乳动物，其肠道微生物在宿主高原适应性方面发挥着重要作用，同时，作为野生动物，它们的肠道微生物也可能携带抗生素抗性基因并将其传播给人类，造成抗生素药物失效。因此，对这两个物种肠道微生物组和抗生素抗性基因的研究十分重要。本研究通过16S rRNA基因测序，定量PCR等技术获得两物种肠道菌群特征并检测到了抗生素抗性基因。结果发现，在门水平上，高原鼢鼠肠道拟杆菌门（Bacteroidetes）的相对丰度更高；而高原鼠兔肠道厚壁菌门（Firmicutes）和放线菌门 ...
冯天舒 1 俞巧玲 1 周蕊 1 王逸洁 1 苏军虎 2 李欢 1 +1 more
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Oral Safety and Gut Microbiota Regulatory Effect of Cellulose Nanocrystals [PDF]
Objective: This study was conducted to investigate the oral safety and gut microbiota regulatory effect of cellulose nanocrystals (CNC) prepared by sulfuric acid hydrolysis (S-CNC) or phosphoric acid hydrolysis (P-CNC).
MING Liangshan, XIAO Nan, LIU Ao, XIAO Zijian, LIU Hongning, LI Zhe
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A Review of the Role of Probiotics and Prebiotics in Improving Postpartum Obesity Based on Intestinal Microecology [PDF]
As the country has loosened its family planning policy and living standards have improved, postnatal obesity has become a social problem seriously threatening public health in China, which has attracted widespread attention from all walks of life ...
MA Wenlong, HU Linlin, KANG Wenli, HAN Yifeng, LI Yisi, YAN Xiantao, PAN Lina, WANG Jiaqi, GU Ruixia
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Zhongshan Daxue xuebao. Yixue kexue ban, 1999 目的: 研究萎缩性阴道炎患者的阴道菌群分布情况。方法: 收集萎缩性阴道炎病人 50 例、绝经前健康妇女 30 例 和绝经后阴道萎缩妇女 20例, 进行阴道需氧菌和厌氧菌培养。结果: 50 例萎缩性阴道炎组共分离出需氧菌 65 株,分离率由高 到低前 4位依次是大肠埃希氏菌( 13/50,26%)、表皮葡萄球菌( 9/50, 18%)、粪链球菌( 7/50, 14%)和绿色链球菌( 6/50, 12%) , 分离出厌氧菌 56株, 分离率由高到低前 4 位依次是拟杆菌( 21/50,42%) 、消化链球菌(
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Effects of Low-carbon and High Protein Bread Diet on Blood Lipid, Immune Index and Intestinal Flora in Mice [PDF]
Objective: To observe the effects of low carbohydrate and high protein diet (LC-HP) and high oil and high sugar diet on blood lipid, immune index and intestinal flora in mice. Use of high protein gluten as the main ingredient to make bread as the diet of
Dajun LI, Yuchun JIANG, Yuhang XIAO
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