Results 91 to 100 of about 2,568 (155)

Postbiotics Regulate Intestinal Microbiota and Reduce Amyloid β-Protein Deposition in the Brain, Thereby Ameliorating Cognitive Impairment in Rats with Alzheimer’s Disease [PDF]

open access: yes
This study aimed to investigate the impact of three postbiotics at different doses on cognitive function in a rat model of Alzheimer’s disease (AD) induced by D-galactose combined with AlCl3. Specific pathogen-free (SPF) Wistar rats were randomly divided
XIAO Ling, TANG Linlin, SONG Xiaoyan, ZHANG Yihua, HAN Xuemei, LÜ Houjiao, LIANG Wu, WANG Yanping, GENG Weitao, JIA Longgang
core   +1 more source

内蒙古赤峰地区东北马鹿(Cervus elaphus xanthopygus)冬季肠道微生物多样性研究

open access: yes野生动物学报, 2020
基于16S rRNA基因测序技术对24份东北马鹿冬季粪便中细菌的结构和多样性进行分析,试图揭示东北马鹿冬季肠道微生态,为该物种保护提供新的见解。结果表明东北马鹿粪便样品中菌群分属于21门33纲74目131科306属,在门水平上,马鹿肠道菌群主要由厚壁菌门(Firmicutes)和拟杆菌门(Bacteroidete)构成,相对丰度分别为79.43%和6.64%;在属水平上,马鹿肠道菌群主要由Ruminococcaceae_UCG-005和Christenseenellaceae_R-7_group构成 ...
郭金昊   +3 more
doaj  

Effects of Low-carbon and High Protein Bread Diet on Blood Lipid, Immune Index and Intestinal Flora in Mice [PDF]

open access: yes
Objective: To observe the effects of low carbohydrate and high protein diet (LC-HP) and high oil and high sugar diet on blood lipid, immune index and intestinal flora in mice. Use of high protein gluten as the main ingredient to make bread as the diet of
Dajun LI, Yuchun JIANG, Yuhang XIAO
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肠道菌群和胆汁酸代谢在多囊卵巢综合征发病机制中的作用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban
多囊卵巢综合征(PCOS)是育龄期女性最常见的内分泌疾病之一,以排卵功能障碍、高雄激素血症及卵巢多囊样改变为核心特征,是导致女性不孕的主要原因,全球患病率达6%~20%。由于PCOS的复杂性和异质性,其发病机制目前尚未完全阐明,现有证据证明肠道菌群失调和胆汁酸代谢异常可能参与PCOS的发病过程。PCOS患者肠道菌群a多样性下降,产丁酸盐菌减少和拟杆菌属等有害菌增殖,导致肠道屏障受损和慢性炎症,并通过短链脂肪酸与性激素代谢失调加剧胰岛素抵抗和高雄激素血症。PCOS患者胆汁酸代谢异常表现为总胆汁酸水平升高 ...
林康毅, 鄞国书
doaj  

虎纹蛙肠道微生物结构与功能分析

open access: yes野生动物学报, 2020
利用高通量测序方法对虎纹蛙前肠、中肠和后肠微生物结构和功能进行分析。结果表明,虎纹蛙(Rana rugulosa)肠道核心菌群是厚壁菌门(Firmicutes)、变形菌门(Proteobacteria)、拟杆菌门(Bacteroidetes)、梭杆菌门(Fusobacteria)和放线菌门(Actinobacteria)。Romboutsia属、鲸杆菌属(Cetobacterium)、叶杆菌属(Phyllobacterium)是绝对优势菌属。肠道中存在弧菌(Vibro)、邻单胞菌(Plesiomonas)
刘文舒   +5 more
doaj  

Research Progress of Sea Cucumber Polysaccharides on the Structure, Health Efficacy and Mechanism [PDF]

open access: yes
Sea cucumber polysaccharides (SCPs) are characterized by their unique structural configurations and broad-spectrum bioactivities, which are manifested through their regulatory functions or interactions with microbial communities upon entering the ...
Biyi CHEN   +6 more
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Preventive Effect of Lactobacillus paracasei FZU103 on Alcoholic Liver Injury in Mice [PDF]

open access: yes
Objective: To explore the preventive effect of Lactobacillus paracasei FZU103 (LP-FZU103) on alcoholic liver injury (ALI). Methods: Altogether 36 specific pathogen free- (SPF-) grade ICR mice were randomly divided into three groups: control, model and ...
LIANG Zihua, LI Jiayi, XIE Linhui, YANG Ziyi, YOU Shize, WU Chao, LI Wenlong, AI Lianzhong, NI Li, LÜ Xucong, CHEN Youting
core   +1 more source

萎缩性阴道炎阴道菌群的研究

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1999
目的: 研究萎缩性阴道炎患者的阴道菌群分布情况。方法: 收集萎缩性阴道炎病人 50 例、绝经前健康妇女 30 例 和绝经后阴道萎缩妇女 20例, 进行阴道需氧菌和厌氧菌培养。结果: 50 例萎缩性阴道炎组共分离出需氧菌 65 株,分离率由高 到低前 4位依次是大肠埃希氏菌( 13/50,26%)、表皮葡萄球菌( 9/50, 18%)、粪链球菌( 7/50, 14%)和绿色链球菌( 6/50, 12%) , 分离出厌氧菌 56株, 分离率由高到低前 4 位依次是拟杆菌( 21/50,42%) 、消化链球菌(
doaj  

高原鼠兔和高原鼢鼠肠道微生物组及常见抗生素抗性基因的比较

open access: yes野生动物学报, 2020
高原鼠兔和高原鼢鼠是青藏高原的两种优势小型哺乳动物,其肠道微生物在宿主高原适应性方面发挥着重要作用,同时,作为野生动物,它们的肠道微生物也可能携带抗生素抗性基因并将其传播给人类,造成抗生素药物失效。因此,对这两个物种肠道微生物组和抗生素抗性基因的研究十分重要。本研究通过16S rRNA基因测序,定量PCR等技术获得两物种肠道菌群特征并检测到了抗生素抗性基因。结果发现,在门水平上,高原鼢鼠肠道拟杆菌门(Bacteroidetes)的相对丰度更高;而高原鼠兔肠道厚壁菌门(Firmicutes)和放线菌门 ...
冯天舒 1 俞巧玲 1 周蕊 1 王逸洁 1 苏军虎 2 李欢 1   +1 more
doaj  

A Review of the Role of Probiotics and Prebiotics in Improving Postpartum Obesity Based on Intestinal Microecology [PDF]

open access: yes
As the country has loosened its family planning policy and living standards have improved, postnatal obesity has become a social problem seriously threatening public health in China, which has attracted widespread attention from all walks of life ...
MA Wenlong, HU Linlin, KANG Wenli, HAN Yifeng, LI Yisi, YAN Xiantao, PAN Lina, WANG Jiaqi, GU Ruixia
core   +1 more source

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