微生物与人体免疫系统的互动一直是生物医学研究的焦点。新一代测序发现不仅肠道,呼吸道也存在着微生物群,且肠-肺微生物群之间通过免疫细胞及其活性因子等形成了一个相互关联的网络。本综述旨在探讨肠道和肺部微生物群如何调节免疫应答,包括其在局部和全身免疫调节中的作用;同时,解析肠-肺轴之间的免疫联系,对深入理解微生物在免疫系统的作用及探索新的疾病诊疗策略具有重要临床意义。
张萌, 杨正飞
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Generation Mechanism of Gut-Derived Short Chain Fatty Acids and Its Dietary Regulation(肠源性短链脂肪酸生成机制及其饮食调控) [PDF]
Short chain fatty acids (SCFAs), as important metabllites of gut microorganisms, organically link the complex interactions between host nutrition and gut microbiota.
HE Fang(何方) +2 more
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Progress in Understanding the Relationship between Diabetes and Host Intestinal Microbiota and Diet-Mediated Microbiota Regulation [PDF]
Diabetes is a metabolic disease characterized by insulin secretion disorder. When serious, it can cause various complications (cardiovascular and cerebrovascular diseases, cataract and other eye diseases, kidney disease and cancer), bringing a huge ...
WANG Danping, XU Jinzhao, ZHANG Xiaohang, NING Ke, LIU Ye, XU Yuanzhi, XIE Qinggang, XU Xiaoxi
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Progress in Culturemics Research on Beneficial Intestinal Bacteria [PDF]
Gut microbes especially the beneficial ones play an important role in maintaining human health. At present, the research methods for intestinal microbes are mainly based on non-culture technologies such as metagenomics.
YU Xia, ZHAO Feiyan, SUN Zhihong
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Correlation of immune function: gut microbiota and radiation enteritis in patients with cervical cancer [PDF]
Objective To investigate the relationship of immune function and gut microbiota with radiation enteritis (RE) in patients with cervical cancer. Methods Clinical data of 80 patients with cervical cancer were retrospectively analyzed.
Jing Wenjiang, Chen Jiaqi, Luo Ruonan, Ma Wu
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Effects of Human Gut Microflora on Stability of Wine Anthocyanins in vitro(体外模拟人肠道微生物对葡萄酒花色苷稳定性的影响) [PDF]
The influence of intestinal microflora on the stability of wine anthocyanins and the relationship between anthocyanin structure and stability were analyzed, which is helpful for understanding the digestion and absorption of anthocyanins and improving ...
LIU Yangjie(刘杨洁) +4 more
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Novel Developments in the Relationship of Gut Microbiota and Immune Regulation with Childhood Asthma [PDF]
Bronchial asthma, commonly known as asthma, is a frequently seen chronic respiratory disease that seriously threatens human health. More than 300 million people have had asthma worldwide, and most of them are children. Epidemiological investigations have
CUI Tianyi, LIU Jiarui, LYU Bin, GAO Xiumei, ZHAO Xin
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Research progress on sugar substitutes and human health [PDF]
Sugar reduction and restriction have become one of the most urgent health demands as the number of obese people increases globally. Sugar substitutes (mainly classified into sugar alcohols, natural sweeteners, and artificial sweeteners) have been widely ...
Mengying QU +4 more
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Gut Microbiota—A New Concern on Health Regulation(肠道菌群:膳食与健康研究的新视角) [PDF]
With the development of “Human Microbiome Project” and “Metagenomics of the Human Intestinal Tract”, great attention has been paid on human gut microbiota. With the increasing knowledge of the composition and function of gut microbiota, we found that gut
CHEN Wei(陈 卫)
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Generation Mechanism of Gut-Derived Trimethylamine and Its Dietary Regulation(肠源性三甲胺生成机制及其饮食调控) [PDF]
Substances such as choline, L-carnitine, and betaine contained in food can be converted into trimethylamine (TMA) under the action of gut microbiota. TMA can be easily absorbed by intestinal epithelial cells, transported to the liver through the portal ...
WANG Shijie(王世杰) +1 more
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