Results 31 to 40 of about 1,524,900 (144)
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
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Veterinary Dermatology, Volume 36, Issue 2, Page 148-158, April 2025.Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Bhumika F. Savaliya +3 more
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, 2019 水产养殖过程中抗生素的过度使用导致耐药菌株不断出现,细菌耐药性成了威胁公共安全的一个全球性问题。抗性基因是细菌产生耐药性的根本原因,动物肠道微生物是抗性基因的储存库,目前我国对水产养殖动物消化道微生物抗生素抗性基因的研究匮乏。为探究草鱼(Ctenopharyngodon idellus)肠道微生物中抗性基因的类型和丰度,通过提取草鱼肠道内容物的基因组DNA,采用shotgun宏基因组技术进行测序和序列注释,分析草鱼肠道内容物微生物数据,对比抗性基因数据库ARDB筛选出微生物序列中的抗性基因。结果表明 ...
吴山功 +4 more
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浙江大学学报. 农业与生命科学版The gut microbiota-gut-brain axis is a bidirectional communication pathway established between the gut microbiota, the gut, and the central nervous system.
ZHOU Qian(周倩) +2 more
doaj +1 more source
野生动物学报, 2021 动物肠道中寄生着数以亿计的微生物,参与到动物机体中如代谢和免疫等重要的生理过程中。然而,在粪便等复杂样本中包含着大量微生物,无法通过纯培养技术进行研究,无法评估样本中的微生物多样性。通过宏基因组学技术可以对微生物群总DNA进行分析,使其成为目前研究复杂样本微生物结构和功能的重要工具。并且伴随高通量测序技术和生物信息学的进步,对微生物的分析流程也在不断地被改进。本文比较了在宏基因组学中普遍应用的标志基因扩增子分析和全宏基因组分析,对宏基因组技术在几类野生脊椎动物肠道微生物领域中的应用进行综述 ...
赵宇卓 吴 尽 杨天雄 姚茂林 裴 欣 付蓝仪 刘学东
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Integrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang +10 more
wiley +1 more source
Veterinary Dermatology, Volume 35, Issue 4, Page 375-385, August 2024.Background – Perianal fistulas are painful ulcers or sinus tracts that disproportionately affect German shepherd dogs and are proposed as a spontaneous animal model of fistulising Crohn's disease. Objectives – To characterise the rectal and cutaneous microbiota in German shepherd dogs with perianal fistulas and to investigate longitudinal shifts with ...
Christine L. Cain +6 more
wiley +1 more source
Zhongguo youzhi, 2022 为了进一步开发与应用元宝枫籽油，研究了元宝枫籽油对高脂膳食小鼠脂代谢及肠道健康的影响。将60只小鼠分为空白组、模型组、元宝枫籽油高剂量组〔1 200 mg/(kg·d）〕和低剂量组〔600 mg/(kg·d）〕，连续灌胃60 d。实验结束后，测定小鼠生长状况、血脂水平、盲肠微环境指标和盲肠内容物短链脂肪酸及微生物菌群。结果表明：与模型组相比，元宝枫籽油高剂量组能显著降低小鼠体质量、腰围、Lee′s指数、腹腔脂肪质量，显著降低小鼠盲肠内容物中游离氨、氨态氮、硫化氢和pH，显著增加盲肠内容物中丁酸 ...
安玉红1，关天琪1，郭艳红1，李慧1,梁世康2，黄涛2 AN Yuhong1，GUAN Tianqi1，GUO Yanhong1，LI Hui1，LIANG Shikang2，HUANG Tao2
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Veterinary Dermatology, Volume 35, Issue 3, Page 325-336, June 2024.Background – Norway spruce (Picea abies) resin‐based products are used in human medicine. A resin‐based otic rinse also could be useful in supportive care of canine otitis externa (COE), yet information on its antimicrobial effect against canine pathogens or ototoxicity is lacking.
Elina Aimo‐Koivisto +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目的近年来我国的病原生物安全防护工作越来越被重视,所以在医学病原微生物肠道杆菌实验教学中,根据卫生部公布的《人间传染的病原微生物名录》,将肠道致病微生物列为第二类病原微生物,属高致病性病原微生物。方法所以在教学中肠道致病伤寒杆菌减毒株的研究迫在眉睫,特此设计了肠道伤寒杆菌的减毒株实验。结果通过肠道伤寒杆菌减毒株实验,使得肠道伤寒实验无毒性,保持生物学性状。结论避免了学生病原微生物学实验中的感染,提高了病原微生物实验教学的安全性,保证医学高校学生学习到真正的肠道致病菌的生化特性,同时保证了生物安全。
于军, 贺丹, 张灵, 李洪岩
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