Effects of Saponins of Semen Ziziphi Spinosae on Oxidative Damage of Liver and Kidney and Intestinal Microflora in Lead-exposed Mice [PDF]
Objective: To investigate the effects of saponins of Semen Ziziphi Spinosae (SSZS) on liver and kidney oxidative damage and intestinal flora composition in lead-exposed mice and explore its detoxification mechanism. Methods: The Pb-intoxicated mice model
Lihong LIU, Weidong CAO
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Zhongguo shiyan zhenduanxue, 2019 目的近年来我国的病原生物安全防护工作越来越被重视,所以在医学病原微生物肠道杆菌实验教学中,根据卫生部公布的《人间传染的病原微生物名录》,将肠道致病微生物列为第二类病原微生物,属高致病性病原微生物。方法所以在教学中肠道致病伤寒杆菌减毒株的研究迫在眉睫,特此设计了肠道伤寒杆菌的减毒株实验。结果通过肠道伤寒杆菌减毒株实验,使得肠道伤寒实验无毒性,保持生物学性状。结论避免了学生病原微生物学实验中的感染,提高了病原微生物实验教学的安全性,保证医学高校学生学习到真正的肠道致病菌的生化特性,同时保证了生物安全。
于军, 贺丹, 张灵, 李洪岩
doaj
野生动物学报, 2021 罗氏鼢鼠（Myospalax rothschildi）是陕西南部农区主要害鼠，研究其与当地环境的相互作用对鼠害防控有重要意义。肠道微生物对宿主行为及生理的调控机制是近年来啮齿类动物防控研究新方向。本研究通过Illumina 高通量测序技术，对雌性罗氏鼢鼠的盲肠样品进行 16S rRNA V3V4区的高通量测序，分析性别及食物因素对罗氏鼢鼠肠道细菌多样性的影响。结果显示，雌性罗氏鼢鼠的肠道内容物中的细菌隶属10门9纲11目13属。肠道革兰氏阳性厚壁菌门（Firmicutes）和革兰氏阴性菌类的变形菌门 ...
陈晓宁 封托 侯祥 安晓雷 王京 常罡
doaj
Fecal Microbiota Transplantation Induces HBeAg Clearance in Patients with Chronic Hepatitis B with Persistent Positive HBeAg [PDF]
, 2017 背景和目的：慢性乙型肝炎（ChronichepatitisB，CHB）在世界范围内流行，且经过长时程口服抗病毒治疗后仅有少数患者能达到停药标准。粪菌移植（FecalmicrobiotaTransplantation，FMT）已被证明可以诱导缓解多种临床疾病，包括艰难梭菌相关性结肠炎。在本研究中，我们探索了粪菌移植对长期核苷/酸类似物（nucleos(t)ideanalogues，NAs）治疗后HBeAg仍未实现血清学阴转的CHB患者的治疗价值。 实验方法：在该开放性、单盲 ...
任艳丹
core
Research Progress in Short-Chain Fatty Acid Modulation of the Gut-Bone Axis in Bone Metabolism [PDF]
As global aging intensifies, the incidence of age-related bone metabolic disorders, such as osteoporosis, continues to climb. Seeking safe and effective therapeutic interventions is of utmost importance.
ZHANG Xuan, YANG Xue, LI Xinke, MENG Lu, WANG Jiaqi, ZHENG Nan
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Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases [PDF]
, 2023 Ketogenic diets have been shown to play a role in some metabolic diseases and neurodegenerative diseases as a low-carbohydrate, high-fat diets supplemented with appropriate protein. Ketogenic diets have been proven effective, but the mechanisms of action
Jian LI +5 more
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野生动物学报, 2021 肠道微生物是一个复杂的生态系统，与宿主的健康、疾病以及其他因素有着密切的关系。目前，关于肠道菌群结构和功能的研究较多，但是对西伯利亚狍肠道菌群的研究还未见报道。西伯利亚狍（Capreolus pygargus）属于反刍动物，有独特的消化特性和微生物群来帮助它们适应高纤维的食物。本研究利用高通量测序技术在Illumina MiSeq平台上对14只狍肠道微生物进行16S rRNA基因分析。结果表明：个体样本中门类组成的差异，雌性个体JY3和雄性个体JY9除Firmicutes，Bacteroidetes ...
刘金月 刘德凯 王璐瑶 李响 贾博文 刘艳华
doaj
Effect of Acer truncatum Seed Oil on Physiological Indicators and Intestinal Flora in Aging Drosophila melanogaster [PDF]
The aim of this study was to explore the effect of Acer truncatum seed oil (ATO) on physiological indicators and the intestinal flora in aging Drosophila melanogaster. Wild-type D.
LI Xiujuan, WEI Jingjing, CHAI Xuejun, LIU Yafei, HUANG Junlang, LIU Wei, CHEN Shulin, ZHU Xiaoyan, ZHAO Shanting
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Research progress on the relationship between lung microbiome and lung cancer [PDF]
, 2023 Lung cancer is the leading cause of cancer-related deaths worldwide. Lung microbiome is defined as the microbial organisms located in the lung. With rapid development of next-generation sequencing， microbiome has been found to affect the host’s nutrition，
Ge Yijun, Cao Chao
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Analysis of gut microbiota changes in alcoholic fatty liver disease in progression based on 16S rDNA sequencing technology [PDF]
Objective To analyze the changes of gut microbiota in the progression of alcoholic fatty liver disease(AFLD) using 16S rDNA sequencing technology, and to explore the possible mechanism of AFLD progression in mice.
DONG Xiaowei +5 more
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