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儿童青少年超重肥胖诊断与管理华南专家共识(2025) [PDF]
儿童青少年超重及肥胖症的发病率上升,已成为中国及全球重大公共卫生问题。中国华南地区儿童青少年的超重率和肥胖率位于全国的较低水平,其独特的气候、文化、饮食习惯有利于儿童青少年超重肥胖防控工作的开展。本共识基于华南地区超重和肥胖症儿童青少年减重的实践经验,结合循证医学证据,系统构建了儿童青少年超重肥胖症的规范化诊疗体系,涵盖诊断与评估、生活方式干预、行为干预、药物治疗和中医治疗等内容。本共识将地域性特征纳入儿童青少年超重和肥胖管理框架,旨在为临床工作者提供兼具科学性与实操性的指导方案 ...
广东省保健协会儿童内分泌遗传代谢分会 +4 more
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Objective To understand the feelings and to explore the motivations of domestic obese people undergoing bariatric surgery. Methods Phenomenological research design and semi-structural interviews were conducted on 15 obesity patients who undergoing ...
XU Mengyu (徐梦瑜) +4 more
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Effect of intramuscular adipose tissue in the skeletal muscle of thigh on glucose metabolism in male patients with obesity [PDF]
Objective·To investigate the correlation between intramuscular adipose tissue (IMAT) content and glucose metabolism in male patients with obesity.Methods·Eighty male patients with obesity were recruited from the Endocrinology Department of Renji Hospital,
DONG Ying +5 more
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Combined effects of intermittent fasting and thermogenic fat activation on the treatment and prevention of obesity in mice [PDF]
Objective·To investigate the effects of intermittent fasting (IF) combined with thermogenic fat activation on the treatment and prevention of obesity in mice.Methods·Male C57BL/6J mice aged 8 weeks were fed by high-fat diet for 4 months and then used as ...
MA Jing, WU Kaimin, ZHAO Xuyun
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Inulin Molecular Detection Methods of High-Performance Gel FiltrationChromatography and Changes in Inulin Molecular Weight During Storage [PDF]
菊芋是一种耐盐抗旱植物,可用于生产菊糖.菊糖具有良好的生物活性,其活性受到聚合度的影响.本研究对比了各项条件,总结得到了一套可以用于测定菊糖相对分子量的高效凝胶过滤色谱(HPGFC)方法:纯水为流动相,0.8 m L/min洗脱,Shodex OHpak SB-804HQ色谱柱检测,柱温控制在30℃,样品进样量为每次20μL,检测器为示差折光检测器(RID),采用Sigma公司生产的右旋糖酐标准品,绘制二次方的标准曲线,检测菊糖的相对分子质量.同时利用确定的凝胶过滤色谱(GFC)方法 ...
李琬聪 +4 more
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近年来,随着治疗技术的不断提升,减重代谢手术已成为治疗病态肥胖的首选治疗方法,然而,肥胖患者仍会伴随很多相关并发症,如心脑血管疾病、呼吸系统疾病、关节肌肉疾病以及代谢相关综合征,上述并发症在围术期给麻醉医生带来极大的挑战,并严重影响着手术结果。麻醉用药右美托咪定是一种新型a2肾上腺素受体激动剂,其独特药理和代谢的特点,使得右美托咪定在临床麻醉中的应用更加广泛,但目前其在肥胖患者减重手术中的相关研究鲜少。本文将围绕右美托咪定在病态肥胖患者减重代谢手术中的应用进展作一概述。
俞贝贝 +4 more
doaj
目的 研究肥胖与症状性颅内动脉粥样硬化狭窄(symptomatic intracranial atherosclerosis stenosis,sICAS)患者跨病变压力比(pressure ratio,PR)减低的关系。 方法 本研究数据来源于中国国家卒中登记Ⅲ数据库。纳入数据库中具有HR-MRI影像学资料的sICAS患者进行分析。采用TOF-MRA成像进行网格建立,采用有限元方法进行建模获得压力值。血管狭窄远端压力和近端压力的PR≤0.76表示狭窄后残余血流减低。按患者BMI分为低或正常体重组 ...
王安琪1,2,3,4,王安心1,2,3,4,张怡君1,2,3,4,姜勇1,2,3,4,张亚清1,2,3,4,刘丽1,2,3,4,付胜奇5, 秦海强1,2,3,4,刘改芬1,2,4,6
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FTO、MC4R、SH2B1与肥胖T2DM的关联及基因间交互作用研究
2型糖尿病(T2DM)是由遗传和环境因素引起的复杂疾病。目前,全球有4.63亿糖尿病患者,到2045年糖尿病的发病人数将增加到7亿[1]。在中国,糖尿病的发病率为10.9%,在超重和肥胖人群中,该值甚至更高[2]。有研究显示糖尿病和肥胖症可以独立遗传亦可共同遗传,甚或糖尿病是引起肥胖的病因[3]。肥胖者体内的非酯化脂肪酸、细胞因子、促炎性标志物等水平的升高与胰岛素抵抗发生发展相关,这些因素可导致T2DM的发生[4]。因此,阐明糖尿病的发病机制非常重要。
耿力, 连明珠, 赵莹, 陈琰
doaj
Relationship between abnormal symptoms of Prader-Willi syndrome model --Snord116 deletion mice and Ghrelin signaling pathway [PDF]
Prader–Willi综合症是以进食异常和血液Ghrelin异常升高为特征的遗传肥胖症。其病因是Snord116SnoRNA群的表达缺失。我们构建的Snord116del小鼠模型表现出贪食和血液Ghrelin升高等PWS症状。此次研究中,我们繁育野生型(WT)、Snord116del(SW)、Ghrl-/-(WG)、Ghsr-/-(WR)小鼠,并制备[Snord116del,Ghrl-/-](SG)和[Snord116del,Ghsr-/-](SR)双敲除小鼠,对其生长发育 ...
甘利芬
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Public attitude and knowledge of stuttering in Hong Kong and mainland China [PDF]
Stuttering is a fluency disorder characterized by stoppage of speech at an abnormally high rate and duration (Guitar, 2006). The present study aims at studying the public attitudes (beliefs, self-reactions and knowledge) towards stuttering in Hong Kong ...
Ip, Man-ling, 葉敏鈴
core

