Results 21 to 30 of about 1,877 (114)

Ceramide changes in abdominal subcutaneous and visceral adipose tissue among diabetic and nondiabetic patients 糖尿病和非糖尿病患者腹部皮下和内脏脂肪组织神经酰胺的变化

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 271-281, April 2022., 2022
Highlights The gender‐specific role of sphingolipids in obesity‐related metabolic dysfunctions is unclear. The aim of this study is to identify ceramide species by liquid chromatography‐mass spectrometry that accumulate in central fat in relation to status of diabetes and gender for subjects with a body mass index ≥40 kg/m2 or > 35 kg/m2 with ...
Michelle Brusatori   +7 more
wiley   +1 more source

MMC celebrating 6 years of experience and expansion 庆祝MMC六年的经验和壮大

open access: yes, 2022
Journal of Diabetes, Volume 14, Issue 5, Page 356-357, May 2022.
Itamar Raz
wiley   +1 more source

COVID‐19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity? 新冠肺炎与合并症:二肽基肽酶4在疾病严重程度中的作用?

open access: yesJournal of Diabetes, Volume 12, Issue 9, Page 649-658, September 2020., 2020
Highlights Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2; recent modeling of the structure of SARS‐CoV‐2 spike glycoprotein, which mediates viral‐host‐cell entry, predicts interactions with dipeptidyl peptidase 4 (DPP4) in addition to angiotensin‐converting enzyme 2.
Margaret F. Bassendine   +3 more
wiley   +1 more source

The Jiangnan diet, a healthy diet pattern for Chinese 江南饮食——一种健康的中国传统饮食模式

open access: yesJournal of Diabetes, Volume 12, Issue 5, Page 365-371, May 2020., 2020
Highlights To explore the localized “Mediterranean diet” for metabolic disorders prevention in China, we review the main healthy diet components, which the native inhabitants in the Yangtze River Delta region have eaten for a long time, and refer to this healthy diet as “Jiangnan Diet.” Abstract Geographically, the Qinling Mountain—Huai River line ...
Jiqiu Wang   +3 more
wiley   +1 more source

Renoprotective effects of brown adipose tissue activation in diabetic mice 棕色脂肪激活对糖尿病小鼠的肾脏保护作用

open access: yesJournal of Diabetes, Volume 11, Issue 12, Page 958-970, December 2019., 2019
Highlights This study demonstrates that of brown adipose tissue (BAT) with CL316,243 attenuates the progress of diabetic kidney disease (DKD). Mechanistically, the activation of BAT improved concentrations of circulating adipokines and microRNAs, which further affected the diabetic kidney and reactivated the AMP‐activated protein kinase/sirtuin 1 ...
Ying‐Ying Cai   +10 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

重庆市重庆大学社区人群中心性肥胖的患病率及其与微量白蛋白尿的相关性调查

open access: yesZhongguo shiyan zhenduanxue, 2011
目的调查重庆市重庆大学社区人群中心性肥胖的患病率,并探讨微量白蛋白尿(MAU)与中心性肥胖的相关性。方法在重庆市重庆大学社区健康体检人群中随机抽取30岁以上者501例,按《中国成人超重和肥胖症预防控制指南》提出腰围切点作为中心性肥胖的诊断标准,分为正常对照组(Con组)和中心性肥胖组(Ob组)。用化学发光法检测MAU,并与相关指标进行相关分析。结果本人群中心性肥胖的患病率为49.7%。Ob组的MAU明显高于Con组,且与年龄、腰围、收缩压和口服葡萄糖耐量试验2小时血糖相关 ...
杜娟   +6 more
doaj  

蒙古族、汉族肥胖者的诊断及瘦素差异与相关因素分析

open access: yesZhongguo shiyan zhenduanxue, 2015
肥胖是一种常见疾病,与瘦素关系密切。瘦素(Leptin),脂肪细胞合成的一种激素,是肥胖基因编码的蛋白质产物,具有广泛的生物学活性,且受体分布广泛,是一种作用于多靶器官、多功能的激素。它可控制能量消耗与食欲,与胰岛素密切相关,多数肥胖个体存在瘦素抵抗且大都存在明显高胰岛素血症。本研究通过对蒙古族、汉族肥胖及非肥胖人群血清瘦素水平、胰岛素水平、血糖的测定,研究蒙古族和汉族肥胖者瘦素水平的差异及与肥胖、胰岛素、
焦雪琴   +4 more
doaj  

肥胖痛风患者尿酸排泄特征分析

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2019
【目的】探索合并肥胖的痛风患者临床特征及尿酸排泄特点。【方法】纳入2013年1月至2018年5月在中山大学孙逸仙纪念医院风湿免疫科住院的痛风患者228例,收集临床资料及空腹血生化指标,测定24h尿尿酸和尿肌酐并计算肾尿酸排泄指标。【结果】根据体质量指数(BMI)把患者分为肥胖组(n=44)、超重组(n=88)及非超重组(n=96),肥胖组年龄小于超重组及非超重组[43(32,57)岁比55(45,65)岁、58(45,67)岁],起病年龄小于非超重组[37(26,48)岁比48(38,59)岁 ...
梁锦坚
doaj  

肥胖患者异丙酚静脉全麻行无痛肠镜中麻醉并发症临床观察

open access: yesZhongguo shiyan zhenduanxue, 2013
众所周知,过度肥胖者心脏负荷增大,心、肺疾病易患率增加。因而过度肥胖者在麻醉中对心脏、呼吸系统有影响的药物应用时应监测循环、呼吸系统的各项指标。本研究通过对肥胖患者异丙酚静脉全麻术行结肠镜检查中麻醉并发症的发生情况进行观察,探讨肥胖在异丙酚静脉全麻中对心脏、呼吸系统的影响。
李秀慧   +3 more
doaj  

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