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儿童青少年超重肥胖诊断与管理华南专家共识(2025) [PDF]
儿童青少年超重及肥胖症的发病率上升,已成为中国及全球重大公共卫生问题。中国华南地区儿童青少年的超重率和肥胖率位于全国的较低水平,其独特的气候、文化、饮食习惯有利于儿童青少年超重肥胖防控工作的开展。本共识基于华南地区超重和肥胖症儿童青少年减重的实践经验,结合循证医学证据,系统构建了儿童青少年超重肥胖症的规范化诊疗体系,涵盖诊断与评估、生活方式干预、行为干预、药物治疗和中医治疗等内容。本共识将地域性特征纳入儿童青少年超重和肥胖管理框架,旨在为临床工作者提供兼具科学性与实操性的指导方案 ...
广东省保健协会儿童内分泌遗传代谢分会 +4 more
doaj +5 more sources
Association between triglyceride glucose index and carotid intima-media thickness in obese and nonobese adults. [PDF]
Highlights Many studies have reported that the triglyceride glucose (TyG) index is an inexpensive biochemical marker to assess metabolic and cardiovascular diseases. Our findings indicate that the TyG index is nonlinearly associated with the risk of new‐onset elevated carotid intima‐media thickness (CIMT) during a follow‐up of 4.3 years.
Jia X +19 more
europepmc +2 more sources
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan +5 more
wiley +1 more source
Highlights Higher creatinine to cystatin C to waist circumference ratio (CCR/WC ratio) was associated with decreased risk of type 2 diabetes mellitus (T2DM) among Chinese people. A nonlinear association was found between CCR/WC and T2DM risk. Abstract Background There is a lack of research regarding the relationship between creatinine to cystatin C to ...
Yinfei Chen +5 more
wiley +1 more source
Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv +6 more
wiley +1 more source
Highlights Laparoscopic sleeve gastrectomy and laparoscopic Roux‐en‐Y gastric bypass are effective for reducing weight and improving metabolic parameters in Chinese patients with obesity. These interventions resulted in improved glycemic control, as evidenced by decreased glycated hemoglobin levels, reduced insulin resistance, and improved ...
Wenhuan Feng +6 more
wiley +1 more source
Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制
Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin +6 more
wiley +1 more source
Highlights In Chinese postmenopausal women with type 2 diabetes mellitus, serum follicle‐stimulating hormone levels were negatively and independently associated with the prevalence of nonalcoholic fatty liver disease. Metabolic conditions, including overweight/obesity, central obesity, hyperuricemia, hypertension, and dyslipidemia did not interact with
Shengjie Ge +10 more
wiley +1 more source
Highlights In people with type 2 diabetes, the risk of all‐cause, cardiovascular disease, and cancer mortality increased with higher gamma‐glutamyl transferase (GGT) concentrations. Stronger effects of GGT levels and all‐cause mortality were observed in the group with body mass index <25 kg/m2 and those with dyslipidemia.
Haoyu Guan +12 more
wiley +1 more source
Highlights Interventional techniques offer novel therapeutic approaches for metabolic disorders such as obesity and type 2 diabetes mellitus, with advantages such as less invasiveness, fewer potential complications, and lower costs. By embolizing specific arteries feeding ghrelin‐producing cells, bariatric arterial embolization not only promotes weight
Zhi Wang +9 more
wiley +1 more source

