Results 21 to 30 of about 4,906 (168)
Highlights Using a large‐scale prospective population‐based cohort study, we found that a higher frequency of daytime napping is associated with an increased risk of incident type 2 diabetes (T2D), and such relations are modified by body fat percentage (BFP) and C‐reactive protein (CRP) levels.
Rui Zhou +9 more
wiley +1 more source
Highlights To our knowledge, our study is the first to date to investigate the association between metabolically defined obesity and adverse outcomes in patients with chronic myeloid leukemia (CML). Metabolic abnormalities were associated with adverse outcomes in patients with CML, irrespective of obesity status.
Yingchun Dong +11 more
wiley +1 more source
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen +11 more
wiley +1 more source
The Association of Retinal age gap with metabolic syndrome and inflammation 视网膜年龄差与代谢综合征和炎症的关系
Highlights Retinal age gap is a non‐invasive and cost‐effective aging biomarker. Retinal age gap was significantly associated with metabolic syndrome and inflammation. Retinal age gap could be potentially used as a screening tool for metabolic syndrome in large populations.
Zhuoting Zhu +13 more
wiley +1 more source
Highlights This is the first large‐sample, multicenter study of the relationship between Chinese Visceral Adiposity Index (CVAI) and urinary albumin to creatinine ratio (UACR) in Chinese community adults. CVAI and UACR were significantly associated in both genders. At higher CVAI levels, the population with prediabetes, diabetes, and hypertension has a
Binqi Li +10 more
wiley +1 more source
Highlights The association between education level and diabetes in Chinese adults is positive in men but negative in women. Obesity is the major mediator underlying the gender disparity in the association between education and diabetes. Combating obesity may help address the burden of diabetes across education levels in both genders.
Yuanyue Zhu +41 more
wiley +1 more source
Highlights In a community‐dwelling Chinese population, famine exposure in early life, especially during the fetal and childhood stages, has an association with an increased risk of metabolic syndrome (MetS) in later life, but the above findings only applied to females, not males.
Yi Zhang +17 more
wiley +1 more source
Childhood obesity in Asia: the value of accurate body composition methodology [PDF]
Childhood obesity, a significant global public health problem, affects an increasing number of low- and middle-income countries, including in Asia. The obesity epidemic has been fuelled by the rapid nutrition and physical activity transition with the ...
Brownie, Sharon +3 more
core +1 more source
Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity [PDF]
孤儿核受体Nur77(也称为TR3)是核受体家族NR4A的一员,在脂肪、肝脏和骨骼肌组织的代谢调控中发挥重要功能,因此被认为是一种新型的治疗代谢性疾病的药物靶点。本文研究中我们发现,在正常生理条件下,随着年龄的增长,Nur77基因敲除的小鼠体重明显高于野生型小鼠。摄食的增多和能量消耗的减少是Nur77基因敲除小鼠体重上升的直接原因。棕色脂肪组织耗能产热功能的衰退也促使了脂肪的积累。原位杂交和实时荧光定量PCR结果显示,Nur77能够正调控瘦素leptin下游厌食多肽POMC的表达。脑室内注射leptin,
肖倩
core +1 more source
Summary Introduction The prevalence of obesity among the Chinese population has increased more than three‐fold over the last twenty years. It is crucial to understand Chinese people's perceptions toward obesity to inform effective weight management initiatives.
Yixi Wang‐Chen +3 more
wiley +1 more source

