Results 21 to 30 of about 4,906 (168)

The association between daytime napping and risk of type 2 diabetes is modulated by inflammation and adiposity: Evidence from 435 342 UK‐Biobank participants 午睡与2型糖尿病风险之间的关联受到炎症和肥胖的调节:来自英国生物样本库(UK‐Biobank) 435 342名参与者的证据

open access: yesJournal of Diabetes, Volume 15, Issue 6, Page 496-507, June 2023., 2023
Highlights Using a large‐scale prospective population‐based cohort study, we found that a higher frequency of daytime napping is associated with an increased risk of incident type 2 diabetes (T2D), and such relations are modified by body fat percentage (BFP) and C‐reactive protein (CRP) levels.
Rui Zhou   +9 more
wiley   +1 more source

Association of obesity under different metabolic status with adverse outcomes in patients with chronic myeloid leukemia: A retrospective cohort study 慢性髓系白血病患者不同代谢状态下肥胖与不良结局的相关性:一项回顾性队列研究

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 436-447, May 2023., 2023
Highlights To our knowledge, our study is the first to date to investigate the association between metabolically defined obesity and adverse outcomes in patients with chronic myeloid leukemia (CML). Metabolic abnormalities were associated with adverse outcomes in patients with CML, irrespective of obesity status.
Yingchun Dong   +11 more
wiley   +1 more source

Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography 通过光学相干断层扫描血管成像检测发现袖状胃切除术改善肥胖队列的微血管表型

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 313-324, April 2023., 2023
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen   +11 more
wiley   +1 more source

The Association of Retinal age gap with metabolic syndrome and inflammation 视网膜年龄差与代谢综合征和炎症的关系

open access: yesJournal of Diabetes, Volume 15, Issue 3, Page 237-245, March 2023., 2023
Highlights Retinal age gap is a non‐invasive and cost‐effective aging biomarker. Retinal age gap was significantly associated with metabolic syndrome and inflammation. Retinal age gap could be potentially used as a screening tool for metabolic syndrome in large populations.
Zhuoting Zhu   +13 more
wiley   +1 more source

A novel index, Chinese visceral adiposity index is closely associated with urinary albumin‐creatinine ratio in Chinese community adults, especially in hypertensive or hyperglycemic population: Results from the REACTION study 一个新的指标, 中国人内脏脂肪指数与中国社区成年人(特别是高血压或高血糖人群)尿白蛋白‐肌酐比值密切相关:来自REACTION研究的结果

open access: yesJournal of Diabetes, Volume 14, Issue 12, Page 792-805, December 2022., 2022
Highlights This is the first large‐sample, multicenter study of the relationship between Chinese Visceral Adiposity Index (CVAI) and urinary albumin to creatinine ratio (UACR) in Chinese community adults. CVAI and UACR were significantly associated in both genders. At higher CVAI levels, the population with prediabetes, diabetes, and hypertension has a
Binqi Li   +10 more
wiley   +1 more source

Obesity mediates the opposite association of education and diabetes in Chinese men and women: Results from the REACTION study 在中国男性和女性中肥胖介导了相反的教育对糖尿病关联:REACTION研究的结果

open access: yesJournal of Diabetes, Volume 14, Issue 11, Page 739-748, November 2022., 2022
Highlights The association between education level and diabetes in Chinese adults is positive in men but negative in women. Obesity is the major mediator underlying the gender disparity in the association between education and diabetes. Combating obesity may help address the burden of diabetes across education levels in both genders.
Yuanyue Zhu   +41 more
wiley   +1 more source

Association between early life famine exposure and risk of metabolic syndrome in later life 生命早期饥荒暴露与晚年代谢综合征风险之间的关联

open access: yesJournal of Diabetes, Volume 14, Issue 10, Page 685-694, October 2022., 2022
Highlights In a community‐dwelling Chinese population, famine exposure in early life, especially during the fetal and childhood stages, has an association with an increased risk of metabolic syndrome (MetS) in later life, but the above findings only applied to females, not males.
Yi Zhang   +17 more
wiley   +1 more source

Childhood obesity in Asia: the value of accurate body composition methodology [PDF]

open access: yes, 2014
Childhood obesity, a significant global public health problem, affects an increasing number of low- and middle-income countries, including in Asia. The obesity epidemic has been fuelled by the rapid nutrition and physical activity transition with the ...
Brownie, Sharon   +3 more
core   +1 more source

Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity [PDF]

open access: yes, 2015
孤儿核受体Nur77(也称为TR3)是核受体家族NR4A的一员,在脂肪、肝脏和骨骼肌组织的代谢调控中发挥重要功能,因此被认为是一种新型的治疗代谢性疾病的药物靶点。本文研究中我们发现,在正常生理条件下,随着年龄的增长,Nur77基因敲除的小鼠体重明显高于野生型小鼠。摄食的增多和能量消耗的减少是Nur77基因敲除小鼠体重上升的直接原因。棕色脂肪组织耗能产热功能的衰退也促使了脂肪的积累。原位杂交和实时荧光定量PCR结果显示,Nur77能够正调控瘦素leptin下游厌食多肽POMC的表达。脑室内注射leptin,
肖倩
core   +1 more source

Exploring the perceptions of Chinese adults toward overweight and obesity: A systematic literature review

open access: yesObesity Reviews, Volume 26, Issue 7, July 2025.
Summary Introduction The prevalence of obesity among the Chinese population has increased more than three‐fold over the last twenty years. It is crucial to understand Chinese people's perceptions toward obesity to inform effective weight management initiatives.
Yixi Wang‐Chen   +3 more
wiley   +1 more source

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