Expert consensus on the precise classification and diagnosis of acute respiratory distress syndrome [PDF]
Acute respiratory distress syndrome (ARDS) is a common critical illness in clinical practice, with a high mortality rate. Given the limited traditional treatment options for ARDS and the high heterogeneity among patients, most clinical trials have failed
Expert Group for Precise Classification and Diagnosis of Acute Respiratory Distress Syndrome
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旋毛虫排泄分泌抗原53-ku重组蛋白上调M2型肺泡巨噬细胞减轻脓毒症小鼠急性肺损伤
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 【目的】探讨重组旋毛虫排泄分泌抗原53-ku蛋白（rTsP53）对小鼠急性肺损伤的保护作用及其机制。【方法】采 用尾静脉脂多糖注射（LPS，10 mg/kg）建立BALB/c小鼠急性肺损伤模型。在肺损伤后2 h尾静脉注射rTsP53（50 μg/只）治 疗。统计各组小鼠72 h累计死亡率，HE染色法观察各组小鼠肺脏病理损伤情况，测量肺脏湿/干质量比（W/D），ELISA法检 测各组小鼠肺泡灌洗液 IL-6 和 IL-4 浓度，RT-PCR 法检测各组小鼠肺泡灌洗巨噬细胞 TNF-α、iNOS、IL-
关开泮 +3 more
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Study of bone marrow mesenchymal stem cell transplantation in the treatment of radiation-induced lung injury [PDF]
, 2014 目的：体外分离培养及鉴定SD大鼠BMSCs，研究BMSCs对放射性肺损伤的治疗作用。方法：1.体外分离、培养、鉴定BMSCs；2.大鼠放射性肺损伤模型的建立；3.通过检测血清TGF-β1、HYP水平，肺组织SOD、MDA含量、PCR扩增Sry基因，研究BMSCs对放射性肺损伤的治疗作用。结果：1.运用密度梯度离心法联合细胞贴壁法可获得纯度较高的BMSCs。BMSCs高表达CD29、CD90表面抗原，低表达CD34、CD45表面抗原。BMSCs可分化为成骨细胞及成脂肪细胞。2.行全胸部20Gy照射 ...
赵兴旺
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Research progress on the pathogenesis of acute lung injury in sepsis [PDF]
Sepsis is a systemic inflammatory response syndrome caused by severe infection leading to host dysfunction，often involving multiple organs and causing functional failure.
WANG Qin，YU Xu，LI Qingying，LU Yibin
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Expressions of IL-1α, IL-1β and IL-13 mRNA in Lung Tissue and Serum of Rats Drown in Fresh Water [PDF]
, 2018 Objective To detect the changes of （interleukin, IL） -1α, IL-1β and IL-13 mRNA in lung tissue and serum of drown rats, and to explore the potential value for the diagnosis of drowning in forensic practice.
JIANG Mei-ling, LIU Zhi-jie, PAN Jing，et al
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Forensic Analysis of 72 Cases with Multiple Organ Dysfunction Syndrome Caused by Traffic Accidents [PDF]
, 2020 Objective To investigate the epidemiological and forensic characteristics of multiple organ dysfunction syndrome （MODS） after severe trauma and explore the reference indexes for determining traumatic MODS.
WANG Yao-bin, GONG Dao-yin, WANG Li-li
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先天性心脏病体外循环术后急性肺损伤患儿磷脂酶A2和白细胞介素6的变化及相关性研究
Zhongguo shiyan zhenduanxue, 2006 目的探讨磷脂酶A2（PLA2）和白细胞介素6（IL-6）在婴幼儿先天性心脏病体外循环（CPB）术后发生急性肺损伤（ALI）的变化及意义。方法采用酶联免疫吸附试验（ELISA）方法对10例先天性心脏病体外循环术后急性肺损伤的婴幼儿、10例先天性心脏病体外循环术后未发生急性肺损伤的婴幼儿和10例来我院门诊健康体检婴幼儿进行白介素6检测;同时对上述3组研究对象应用酶底物显色法检测磷脂酶A2活性 ...
李丽红, 黄艳智, 刘愉
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The effect of glucocorticoids combined with ulinastatin on IL⁃6/IL⁃10 balance and oxygenation index in patients with early acute lung injury after trauma [PDF]
Objective To investigate the clinical efficacy of glucocorticoid combined with ulinastatin in patients with early acute lung injury（ALI）after trauma. Methods A total of 100 patients with early ALI after trauma who admitted to Shengjing Hospital of China ...
LI Tang，WANG Yudong，LI Wenchao
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Relationship between Th1/ Th2 cytokines and severity of acute lung injury secondary to sepsis [PDF]
"Objective To analyze the effects of helper T cells（Th）1 and Th2 cytokines on the severity of acute lung injury（ALI）secondary to sepsis and to analyze their roles in evaluating the occurrence of ALI secondary to sepsis.Methods Clinical data of 206 ...
FU Daoliang，CHEN Dejian，REN Lei，HOU Xiaolin
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Zhongguo shiyan zhenduanxue, 2007 目的探讨多层螺旋CT在大白兔放射性肺损伤中的应用价值。方法40只新西兰大白兔随机分为照射组和对照组,照射组均行右肺单分隔照射建立肺损伤模型,照射后第3、5、7、8、11和14天、第3周、第5周、第8周和第12周分别行MSCT检查,并用pulmo自动评估软件测定双肺的密度值。结果照射后2周内,CT图像无明显改变,利用pulmo自动评估软件分析发现从第7天开始,右肺平均密度高于左肺平均密度 ...
郭岩 +5 more
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