Effects and mechanisms of Pd-Ia on LPS-induced acute lung injury in mice [PDF]
目的:随着环境的不断恶化,空气质量越来越差,并且已经严重影响到了人们的身体健康,雾霾已经遍布中国的众多城市,使得呼吸系统疾病的发病率日渐升高。急性肺损伤(ALI)/急性呼吸窘迫综合征(ARDS)都是比较常见的临床呼吸系统疾病,ARDS对于临床疾病来说,可谓是灾难性的,属于严重的呼吸衰竭,目前无有效的药物治疗措施。ALI是ARDS的早期阶段,其特点是弥漫性的炎症损伤,目前研究发现中药白花前胡根中提取出的活性成分白花前胡甲素(Pd-Ia)在LPS诱导的内皮细胞炎症损伤中具有良好的抗炎效果 ...
周晓霞
core
Correlation between Chlamydia Pneumoniae IgG Positive in Lung Cancer Patients and Cytokines Related to Radiation-induced Pulmonary Lesion [PDF]
Background and objective There exsits intimate relationship between infection with chlamydia pneumoniae (Cpn) and lung cancer incidence. But few studies have been reported about radiation-induced pulmonary lesion in lung cancer patients infected with Cpn.
Daoan ZHOU +3 more
core
早期循证护理对预防重症急性胰腺炎相关性肺损伤的临床 价值研究 [PDF]
Objective: To investigate the severe acute pancreatitis in patient with early application of evidence-based care,where to improve breathing,reduce mortality and shorten the time of ICU.
Li, Jun-lei, Lu, Rong
core +2 more sources
<正>放射治疗是肺癌患者的主要治疗手段之一,可以提高肿瘤的局部控制率。但由于肺是射线敏感器官,其组织细胞容易受到辐射的损坏[1]从而可以引发放射性肺损伤(RILI)。RILI的发病机制可能与炎症反应、肺泡及内皮细胞损伤等有关[2]。在体外研究中,细胞外组蛋白可损伤内皮细胞[3]、刺激细胞因子的释放[4],并可以诱导嗜中性粒细胞细胞外诱捕网的形成和髓过氧化物酶的释放。因此,推测细胞外组蛋白可能作为促炎介质在RILI的发生发展中占据重要地位。本研究拟通过收集接受胸部放疗的肺癌患者并利用细胞实验 ...
刘立杰 +9 more
doaj
Clinical Application of Adjuvant Treatment after Operation in Patients with Stage IIIa Non-small Cell Lung Cancer [PDF]
Background and objective The efficacy of complete resection of the cancer for patients with stage IIIa non-small cell lung cancer (NSCLC) is limited. Synthetic therapy is taken the lead in advocating at present.
Bin ZHANG, Xia ZHANG, Yajie GAO
core
Research progress of immune response regulated by epigenetic modification in pneumonia [PDF]
Pneumonia is one of the most common infectious diseases, and although considerable progress has been made in the diagnosis and treatment of pneumonia, it is still associated with high mortality, prolonged hospitalization, and significant medical ...
HAN Xiao, WANG Qing, ZHANG Xiaobo
core +1 more source
Changes and significance of TLR7/9 and IFN-Ⅰ levels in children with severe mycoplasma pneumoniae pneumonia [PDF]
Objective To investigate the changes and significance of Toll-like receptor 7 (TLR7), TLR9 and type I interferon (IFN-Ⅰ) in children with severe mycoplasma pneumoniae pneumonia (SMPP).
Yan Jiangxue, Ding Xia, Jiao Qiongjie, Huang Li, Cao Nannan, Dong Xinfang, Ni Qian
core +1 more source
This paper summarized the modified prone ventilation treatment and nursing for a elderly patients with pulmonary injury after surgery for suppurative cholecystitis.
LI Xueyan (李学艳) +3 more
doaj +1 more source
A Randomized Phase I/II Trial to Compare Weekly Usage with Triple Weekly Usage of Paclitaxel in Concurrent Radiochemotherapy for Patients with Locally Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Although the guidelines of the National Comprehensive Cancer Network of USA recommend that the standard therapy for locally advanced non-small cell lung cancer (LANSCLC) is concurrent chemoradiotherapy.
Anhui SHI +4 more
core
The relationship between serum IL⁃33,vWF,G⁃CSF and prognosis of acute massive hemorrhage patients with transfusion⁃related acute lung injury [PDF]
Objective To explore the predictive value of serum interleukin⁃33(IL⁃33),von Willebrand factor(vWF),and granulocyte colony⁃stimulating factor(G⁃CSF)for the prognosis of acute massive hemorrhage patients withtransfusion⁃related acute lung injury(TRALI ...
DU Dan*,WEI Ge,WANG Lingxue,LIU Hongbin
core +2 more sources

