Correlation of peripheral blood ZO⁃1 and IL⁃38 levels with lung injury degree in patients with acute respiratory distress syndrome [PDF]
Objective To analyze the changes of zonula occludens⁃1（ZO⁃1）and interleukin⁃38（IL⁃38）levels in peripheral blood of acute respiratory distress syndrome（ARDS）patients with different degrees of lung injury，and their correlations with the degree of lung ...
HE Yanxia，XUE Bing，WU Wenjie，CHEN Xing
core +2 more sources
旋毛虫排泄分泌抗原53-ku重组蛋白上调M2型肺泡巨噬细胞减轻脓毒症小鼠急性肺损伤
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 【目的】探讨重组旋毛虫排泄分泌抗原53-ku蛋白（rTsP53）对小鼠急性肺损伤的保护作用及其机制。【方法】采 用尾静脉脂多糖注射（LPS，10 mg/kg）建立BALB/c小鼠急性肺损伤模型。在肺损伤后2 h尾静脉注射rTsP53（50 μg/只）治 疗。统计各组小鼠72 h累计死亡率，HE染色法观察各组小鼠肺脏病理损伤情况，测量肺脏湿/干质量比（W/D），ELISA法检 测各组小鼠肺泡灌洗液 IL-6 和 IL-4 浓度，RT-PCR 法检测各组小鼠肺泡灌洗巨噬细胞 TNF-α、iNOS、IL-
关开泮 +3 more
doaj
先天性心脏病体外循环术后急性肺损伤患儿磷脂酶A2和白细胞介素6的变化及相关性研究
Zhongguo shiyan zhenduanxue, 2006 目的探讨磷脂酶A2（PLA2）和白细胞介素6（IL-6）在婴幼儿先天性心脏病体外循环（CPB）术后发生急性肺损伤（ALI）的变化及意义。方法采用酶联免疫吸附试验（ELISA）方法对10例先天性心脏病体外循环术后急性肺损伤的婴幼儿、10例先天性心脏病体外循环术后未发生急性肺损伤的婴幼儿和10例来我院门诊健康体检婴幼儿进行白介素6检测;同时对上述3组研究对象应用酶底物显色法检测磷脂酶A2活性 ...
李丽红, 黄艳智, 刘愉
doaj
Relationship between Th1/ Th2 cytokines and severity of acute lung injury secondary to sepsis [PDF]
"Objective To analyze the effects of helper T cells（Th）1 and Th2 cytokines on the severity of acute lung injury（ALI）secondary to sepsis and to analyze their roles in evaluating the occurrence of ALI secondary to sepsis.Methods Clinical data of 206 ...
FU Daoliang，CHEN Dejian，REN Lei，HOU Xiaolin
core +2 more sources
Forensic Analysis of 72 Cases with Multiple Organ Dysfunction Syndrome Caused by Traffic Accidents [PDF]
, 2020 Objective To investigate the epidemiological and forensic characteristics of multiple organ dysfunction syndrome （MODS） after severe trauma and explore the reference indexes for determining traumatic MODS.
WANG Yao-bin, GONG Dao-yin, WANG Li-li
core +1 more source
Zhongguo shiyan zhenduanxue, 2007 目的探讨多层螺旋CT在大白兔放射性肺损伤中的应用价值。方法40只新西兰大白兔随机分为照射组和对照组,照射组均行右肺单分隔照射建立肺损伤模型,照射后第3、5、7、8、11和14天、第3周、第5周、第8周和第12周分别行MSCT检查,并用pulmo自动评估软件测定双肺的密度值。结果照射后2周内,CT图像无明显改变,利用pulmo自动评估软件分析发现从第7天开始,右肺平均密度高于左肺平均密度 ...
郭岩 +5 more
doaj
The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help ...
Changli WANG +7 more
core
Expert consensus on the precise classification and diagnosis of acute respiratory distress syndrome [PDF]
Acute respiratory distress syndrome (ARDS) is a common critical illness in clinical practice, with a high mortality rate. Given the limited traditional treatment options for ARDS and the high heterogeneity among patients, most clinical trials have failed
Expert Group for Precise Classification and Diagnosis of Acute Respiratory Distress Syndrome
core +1 more source
Expressions of IL-1α, IL-1β and IL-13 mRNA in Lung Tissue and Serum of Rats Drown in Fresh Water [PDF]
, 2018 Objective To detect the changes of （interleukin, IL） -1α, IL-1β and IL-13 mRNA in lung tissue and serum of drown rats, and to explore the potential value for the diagnosis of drowning in forensic practice.
JIANG Mei-ling, LIU Zhi-jie, PAN Jing，et al
core +1 more source
蟛蜞菊内酯通过调控miR-142-3p表达对肺炎链球菌感染的肺泡上皮细胞损伤的保护作用及其机制研究
Zhongguo shiyan zhenduanxue, 2021 目的探讨蟛蜞菊内酯(WEL)对肺炎链球菌感染的肺泡上皮细胞损伤的作用及分子机制。方法将肺泡上皮细胞A549分为对照组、感染组、感染组+蟛蜞菊内酯低、中、高浓度(WEL-L、M、H)组、感染组+miR-NC组、感染组+miR-142-3p组、感染组+WEL+anti-miR-NC组、感染组+WEL+anti-miR-142-3p组。酶联免疫吸附法(ELISA)检测IL-6、IL-10水平;流式细胞术检测细胞凋亡;蛋白质印迹(Western blot)法检测蛋白表达;实时荧光定量PCR(RT-qPCR ...
郑大炜 +7 more
doaj