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2014年～2017年某院复治肺结核患者的耐药情况分析 [PDF]
, 2018 目的了解我院复治肺结核涂阳患者的耐药谱,为我院预防和治疗结核病提供依据。方法 2014年1月至2017年12月在我院结核病门诊诊断和治疗的涂阳肺结核患者的痰培养结核分枝杆菌,鉴定为结核分枝杆菌的菌株采用比例法,使用6种抗结核药物[异烟肼(H)、利福平(R)、乙胺丁醇(E)、链霉素(S)、氧氟沙星(Ofx)、卡那霉素(Km)]测试耐药性。结果 350例复治肺结核患者的总耐药率为41.71%(146/350),单药耐药(SDR)率为10.25%,多耐药(PDR)率为6.85%,耐多药(MDR)率为24.57%
卢惠萍
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Zhongguo shiyan zhenduanxue, 2021 潜伏性结核感染(LTBI)是指人体经呼吸道感染结核分枝杆菌后,机体检测呈带菌状态,但无活动性结核病相关临床表现的状态。据统计,目前全球近四分之一人口处于潜伏结核感染状态,我国作为人口大国,每年新增结核病患者已超过100万例,虽近些年来LTBI感染率有所下降,但仍是全球LTBI负担较重的国家之一[1]。医务人员在从事诊疗、护理工作中,面临职业暴露的危险[2],医护人员是潜伏性肺结核感染的高风险人群[3],是普通人群的3倍[4-5]。本研究通过对吉林省某医疗机构内的临床医护人员进行调查 ...
赵薇 +8 more
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Uncovering Xi Jinping's Policy Agenda: Text As Data Approach
The Developing Economies, Volume 63, Issue 1, Page 9-46, March 2025.How many agendas has Xi Jinping put forth and promoted since taking office in 2012, and what are the types of agendas? How much of political attention has each agenda received, and how has the allocation of attention changed over time? We utilize a dataset of presidential statements, speeches, and reports from 2012 to 2022 and employed automated text ...
Jaehwan Lim, Asei Ito, Hongyong Zhang
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2022 目的 研究单核细胞P糖蛋白(Pgp)、多药耐药相关蛋白(MRP)在肺结核病患者外周血中的表达情况,探讨其与多药耐药的相关性。方法 回顾性分析144例肺结核病患者临床资料及同期50例健康体检者资料,采用Trizol法检测Pgp、MRP基因在血清样本中表达情况,根据药敏试验将144例肺结核病患者分为耐药组和初治肺结核病组,分析Pgp、MRP基因在肺结核患者血清中的表达情况,探讨肺结核病患者耐药的影响因素。结果 Pgp、MRP在肺结核病组表达量及阳性率均高于对照组,耐药组Pgp ...
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European Policy Analysis, Volume 11, Issue 1, Page 32-53, Winter 2025.Abstract While much work has looked at how governments responded to the Corona pandemic, little consideration has been given to how the crisis affected party competition and what positions political actors took during this period. How were political actors' positions on COVID‐19 portrayed in daily newspapers? And how can we explain these patterns?
Katja Demler
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Biochemical characteristics and function studies of Esx-1 secretion-associated protein EspL and EspG1 [PDF]
, 2016 由巨噬细胞等人体免疫细胞聚集形成的肉芽肿是结核病的形成标志，肉芽肿的形成在结核分枝杆菌的致病过程中扮演着重要角色，它使被感染的宿主与结核分枝杆菌融合在一起。结核分枝杆菌通过特异性的蛋白分泌系统Esx-1分泌系统将具有毒性作用的毒力因子通过高疏水性的细胞膜分泌到胞外。这些毒力因子与宿主中肉芽肿的形成以及结核分枝杆菌毒性作用有关。EspL是结核分枝杆菌Esx-1分泌系统中的一个重要的蛋白，已有研究表明EspL可能通过影响另外两个毒力因子EspE和ESAT-6的分泌而调控肉芽肿的形成 ...
田双良
core
Zhongguo shiyan zhenduanxue, 2010 目的评价结核杆菌蛋白芯片对肺结核的诊断价值及其影响因素。方法对痰涂片阳性肺结核病患者结核杆菌蛋白芯片和胸部CT扫描结果进行对比,分析肺结核病变范围和类型等因素对结核杆菌蛋白芯片检测的影响。结果结核杆菌蛋白芯片阳性率72.0%,CT诊断阳性率为90.0%,两种方法同时检测阳性率达到96.0%;多个肺野肺结核的结核杆菌蛋白芯片阳性率高于单个肺野 ...
曹军皓, 黄前川, 赵冰红
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Study on the diagnostic value of macrophage migration inhibitory factor in neurosyphilis [PDF]
, 2016 目的： 神经梅毒诊断依赖于实验室检查结果，脑脊液（cerebrospinalfluidrapid，CSF）快速血浆反应素环状卡片试验（rapidplasmareagintest，RPR）常作为神经梅毒的确诊指标，但脑脊液RPR的灵敏度低，易造成漏诊；即使结合脑脊液的其他参数（蛋白和白细胞等），也可能造成神经梅毒的漏诊。巨噬细胞移动抑制因子（macrophagemigrationinhibitoryfactor，MIF）作为一种炎症因子已广泛应用于神经系统疾病的诊断 ...
张亚锋
core
National Essential Public Health Services Programs over the Past Decade Research Report Two：Progress and Achievements of the Implementation of National Essential Public Health Services Programs over the Past Decade [PDF]
, 2022 Background The national essential public health services programs (NEPHSP) is an important project led by the Chinese government to benefit the people, which is a Chinese practice towards universal health coverage.
Lili YOU, Jinhong ZHAO, Xinyue CHEN, Linghe YANG, Meicen LIU, Yuting PAN, Siqi ZHANG, Yuanli LIU
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Zhongguo shiyan zhenduanxue, 2019 据WHO报道,全球有将近1/3人口感染结核杆菌,是发展中国家的高发传染病,肺结核是我国常见传染病之一,占全球总负担的15%,具有患病率高、结核耐药率高的特点[1,2]。近年来,许多活动性肺结核患者常无明显症状及典型影像学改变,不典型肺结核具有发生部位、临床症状和影像学表现不典型的特点,影像学以肺间质改变为主的继发性肺结核是不典型肺结核的一种特殊类型,胸部CT及HRCT是早期诊断的关键 ...
梁晓玉, 尹金植
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