Survival Analysis of 1,742 Patients with Stage IV Non-small Cell Lung Cancer [PDF]
Background and objective At present non-small cell lung cancer (NSCLC) is still the leading cause of death induced by cancer. The aim of this study is to investigate the prognostic factors of advanced NSCLC.
Baohui HAN, Hong PENG, Meili MA
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Lobectomy with Bronchoplasty and Reconstruction of Pulmonary Artery by Minitrauma-technique for Lung Cancer [PDF]
Background and objective To research the effect and practicalbility of lobectomy with bronchoplasty and reconstruction of pulmonary artery by minitrauma-technique for lung cancer.
Jiajun DU +7 more
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Correlations between IGF-IR Expression and Clinicopathological Factors and Prognosis in Patients with Lung Adenocarcinoma [PDF]
Background and objective The incidence of lung adenocarcinoma increases rapidly, and IGF-IR is the key mediator of several growth factors signal transduction, therefore it plays an important role in the proliferation and differentiation of cancer cell ...
Baohui HAN +4 more
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Expression and Significance of gp96 and Immune-related Gene CTLA-4, CD8 in Lung Cancer Tissues [PDF]
Background and objective It has been proven that gp96 plays an important role in specific cytotoxic immune response which is involved in anti-tumor effect in the body.
Haiyan ZHENG +4 more
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Changes on Mitochondrial DNA Content in Non-small Cell Lung Cancer [PDF]
Background and objective It has been proven that the mitochondrial DNA (mtDNA) mutations and content change were associated with increasing risk of tumorigenesis. MtDNA content is significantly reduced in most substantive tumors. The aim of this study is
Hongmei WANG, Jigang DAI
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A meta-analysis of Pemetrexed plus Platinum Chemotherapy versus Gemcitabine plus Platinum Chemotherapy for Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Whether pemetrexed plus platinum (PP) regimen is superior to gemcitabine plus platinum (GP) regimen for patients with advanced non-small cell lung cancer (NSCLC) is unclear.
Jin JIANG +5 more
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目的探讨非小细胞肺癌(NSCLC)组织中VEGF mRNA的表达特点。方法应用RT-PCR方法,检测56例非小细胞肺癌组织和10例良性肺肿瘤组织及正常肺组织的VEGF mRNA的表达情况,并分析其与病理特征之间的关系。结果VEGF mRNA在正常肺组织及良性肺肿瘤组织几乎无阳性表达,而在非小细胞肺癌中84.56%有阳性表达;VEGFmRNA在不同组织类型肿瘤中的表达无统计学差异;在临床分期III期的肿瘤中VEGFmRNA的表达量与临床分期II、I期的肿瘤相比明显过表达,两两组间对比存在统计学差异 ...
李冬, 杨海山
doaj
Clinicopathological Research and Expression of PTEN/PI3K/Akt Signaling Pathway in Non-small Cell Lung Cancer [PDF]
Background and objective It has been known that abnormality of PTEN/PI3K/Akt signal pathway played an important role in initiation of some malignant tumors.
Can XU +3 more
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Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]
Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG +7 more
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目的提出125I粒子组织间植入对肺癌细胞A549的有效剂量,确定125I粒子组织间植入对缩小肺癌肿瘤的有效性。方法建立裸小鼠皮下肺癌移植瘤模型,分三组:对照组、空白组、125I粒子植入组。从粒子植入日起观察记录肿瘤大小变化,绘制肿瘤大小变化曲线。植入粒子后第28天处死动物,取瘤,测量最终体积大小及病理分析。结果肺癌细胞A549粒子植入组和对照组、空白组相比效果明显。结论证实了125I粒子对缩小肺癌肿瘤的有效性。125I粒子计量在0.8 mCi对肺癌细胞A549肿瘤缩小的效果明显。
杨帆 +5 more
doaj

