Results 61 to 70 of about 7,186 (171)
Expression and Clinical Significance of mTOR and PTEN in Non-small Cell Lung Cancer [PDF]
Background and objective It has been proved that mTOR was an important signal transduction molecular and protein kinase regulating cell growth and proliferation, and mTOR could activate the downstream protein effector. PTEN could negatively regulate mTOR
Liang WANG +5 more
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CEA、Cyfra21-1、NSE、Ca50联合检测在肺癌中诊断价值
目的探讨肿瘤标志物CEA、Cyfra21-1、NSE、Ca50联合检测在肺癌中诊断价值。方法应用电化学发光免疫分析及免疫放射分析法对214例肺癌、28例良性病变、32例健康人测定血清肿瘤标志物水平。结果214例肺癌血清肿瘤标志物CEA、Cyfra21-1、NSE、Ca50水平高于良性病变、健康组 ...
陈武, 刘洋, 范艳红, 贺贵福
doaj
Immediate Versus Delayed Topotecan after First-line Therapy in Small Cell Lung Cancer [PDF]
Background and objective How to prolong progression free survival (PFS) and overall survival (OS) of patients with small cell lung cancer (SCLC) has been one of the hottest issues. We retrospectively reviewed our data to compare the survival of immediate
Cong XUE +7 more
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用99mTc-MIBI作为肺肿瘤显像剂,对36例肺部肿瘤病人进行了显像,通过计算中,晚期摄取比值(EUR、LUR),摄取时间比值(URTR)及肺癌指数(LCI)进行分析,以LUR、URTR、LCI为指标,对肺部恶性病变诊断的灵敏度分别为93%、74%和92%。特异性为89%、78时和75%。结果认为99mTc-MIBI肺肿瘤显像对良恶性鉴别诊断有较大临床意义。
doaj
Genetic Fingerprint Concerned with Lymphatic Metastasis of Human Lung Squamous Cancer [PDF]
Background and objective With the most recent introduction of microarray technology to biology, it becomes possible to perform comprehensive analysis of gene expression in cancer cell. In this study the laser microdissection technique and cDNA microarray
Li CHEN +7 more
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肺癌骨转移瘤的DCE-MRI成像特点及与循环肿瘤细胞的相关性研究
肺癌是目前最常见的恶性肿瘤之一,发病率高,恶性程度也高,很多病人发现明显症状时已经是肺癌中晚期,可出现各个不同脏器的转移,其中最常发生转移的部位就是骨骼系统。DCE-MRI可以多参数成像,通过各种参数及曲线类型反映肿瘤组织内血流灌注特征,显示其血管分布情况。而基于肿瘤细胞播散理论,检测循环肿瘤细胞(CTC ...
刘桂锋 +3 more
doaj
肺癌(lung cancer)是当前影响人类健康和生命的恶性肿瘤之一[1]。随着生活环境的变化,肺癌的患病率正逐年增加[2]。已有研究发现,我国每年肺癌发病率正以4.5%的速度上升[3]。目前,肺癌的治疗手段主要是以手术治疗,辅助化疗、放疗、免疫治疗等[4]。而顺铂作为金属铂类络合物,可抑制肿瘤细胞中的DNA复制过程[5]。但肺癌的化疗机理仍有待进一步深入研究。芦丁(Rutin)作为心脑血管类药物,已应用多年[6]。近些年来,芦丁在肿瘤的治疗上也逐渐被报道。本文探讨芦丁联合顺铂对肺癌作用机制。
买世雄 +8 more
doaj
BAG Family Gene and Its Relationship with Lung Adenocarcinoma Susceptibility [PDF]
Background and objective BAG genes (Bcl-2-associated athanogene) belong to a recently discovered multifunctional anti-apoptosis gene family that regulate various physiological processes which include apoptosis, tumorigenesis, neural differentiation ...
Heng WU +9 more
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目的探讨血清肿瘤标记物癌胚抗原(CEA)、肿瘤相关抗原199(CA199)、肿瘤相关抗原125(CA125)、神经特异性烯醇化酶(NSE)水平及联合检测在肺癌诊断中的价值。方法采用电化学发光法检测174例肺癌患者血清CEA、CA199、CA125和NSE水平,并与99例肺良性病变患者、42例健康体检者作对照,分析血清肿瘤标记物CEA、CA199、CA125和NSE在肺癌诊断中的价值。结果①肺癌组患者血清CEA、CA199、CA125和NSE水平明显高于肺良性病变组、健康体检组(P0.05);②CEA ...
张亚男 +4 more
doaj
Clinical Application of Adjuvant Treatment after Operation in Patients with Stage IIIa Non-small Cell Lung Cancer [PDF]
Background and objective The efficacy of complete resection of the cancer for patients with stage IIIa non-small cell lung cancer (NSCLC) is limited. Synthetic therapy is taken the lead in advocating at present.
Bin ZHANG, Xia ZHANG, Yajie GAO
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