Results 61 to 70 of about 7,825 (189)
Zhongguo shiyan zhenduanxue, 2022 肺癌是我国死亡率最高的恶性肿瘤[1]。非小细胞肺癌（NSCLC）作为常见的诊断类型，约占肺癌的85%，其发病隐匿，受目前检测方法限制，约75%NSCLC患者诊断时已为晚期，5年生存率不足20%[2]。目前，临床常用的肺癌血清肿瘤标志物有癌胚抗原（CEA）、糖类抗原125(CA125)、细胞角蛋白片段19(CYFRA21-1)、神经元特异性烯醇化酶（NSE）等，但它们的敏感度均较低，尚难满足肺癌的临床诊断需求，特别是对于早期肺癌的识别[3]。因此，探寻高敏感度、高特异度的新型肿瘤标志物 ...
张浩, 张逊, 孙大强
doaj
A Clinical Observation of Concomitant Therapy of Erlotinib and Whole Brain Radiotherapy in Patients of NSCLC Combined with Brain Metastases [PDF]
, 2009 Background and objective Treatments to brain metastases in patients of NSCLC include operation, chemotherapy and radiotherapy, while the disease control rate of brain lesions is not so good, the media survival time is 4-6 months.
Jing ZHAO, Lihong ZHANG, Qiang FU
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Zhongguo shiyan zhenduanxue, 2015 根据肿瘤统计结果,肺癌是我国男性患者中最常见的癌症类型和最主要的肿瘤致死原因。2000-2005年,我国肺癌的发病人数增加了11.6万,死亡人数增加了10.1万。肺癌5年生存率仅约15.6%,主要原因是约75%的患者在诊断时已属晚期肺癌[1,2]。肺癌可因早期诊断不足而致预后差,从组织学来看,腺癌在肺癌中占38.5%,是最常见的一种类型,由于腺癌呈贴壁式生长 ...
方思月, 杨涟
doaj
The Impact of Smoking Status on the Efficacy of Erlotinib in Patients with Advanced Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective Erlotinib is a targeted treatment for advanced non-small cell lung cancer. Smoking status may be one of influencing factors of the efficacy of erlotinib.
Jinji YANG +5 more
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Immediate Versus Delayed Topotecan after First-line Therapy in Small Cell Lung Cancer [PDF]
, 2010 Background and objective How to prolong progression free survival (PFS) and overall survival (OS) of patients with small cell lung cancer (SCLC) has been one of the hottest issues. We retrospectively reviewed our data to compare the survival of immediate
Cong XUE +7 more
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Expression and Clinical Significance of mTOR and PTEN in Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective It has been proved that mTOR was an important signal transduction molecular and protein kinase regulating cell growth and proliferation, and mTOR could activate the downstream protein effector. PTEN could negatively regulate mTOR
Liang WANG +5 more
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CEA、Cyfra21-1、NSE、Ca50联合检测在肺癌中诊断价值
Zhongguo shiyan zhenduanxue, 2007 目的探讨肿瘤标志物CEA、Cyfra21-1、NSE、Ca50联合检测在肺癌中诊断价值。方法应用电化学发光免疫分析及免疫放射分析法对214例肺癌、28例良性病变、32例健康人测定血清肿瘤标志物水平。结果214例肺癌血清肿瘤标志物CEA、Cyfra21-1、NSE、Ca50水平高于良性病变、健康组 ...
陈武, 刘洋, 范艳红, 贺贵福
doaj
A Novel Method for Detecting p53 Autoantibodies in Sera of Patients with NSCLC [PDF]
, 2009 Background and objective Serum autoantibody detection is useful means for the early diagnosis and prognosis of cancer. So our objective was to synthesize peptide array to analyse p53 autoantibodies in the sera of patients with non small cell lung cancer (
Kai TANG +4 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 1994 用９９ｍＴｃ－ＭＩＢＩ作为肺肿瘤显像剂，对３６例肺部肿瘤病人进行了显像，通过计算中，晚期摄取比值（ＥＵＲ、ＬＵＲ），摄取时间比值（ＵＲＴＲ）及肺癌指数（ＬＣＩ）进行分析，以ＬＵＲ、ＵＲＴＲ、ＬＣＩ为指标，对肺部恶性病变诊断的灵敏度分别为９３％、７４％和９２％。特异性为８９％、７８时和７５％。结果认为９９ｍＴｃ－ＭＩＢＩ肺肿瘤显像对良恶性鉴别诊断有较大临床意义。
doaj
Genetic Fingerprint Concerned with Lymphatic Metastasis of Human Lung Squamous Cancer [PDF]
, 2009 Background and objective With the most recent introduction of microarray technology to biology, it becomes possible to perform comprehensive analysis of gene expression in cancer cell. In this study the laser microdissection technique and cDNA microarray
Li CHEN +7 more
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