Results 71 to 80 of about 7,186 (171)
Zhongguo shiyan zhenduanxue, 2012 恶性肿瘤是威胁人类生命健康的第一杀手,在我国,肺癌是发病第一位的肿瘤。肺癌一经发现,首选手术治疗,术后还需经化疗等综合方法进行治疗。在各种疗法中,化疗在肿瘤治疗中占有不可替代的位置。但是,化疗由于用药量大,副作用多,有的患者难以耐受,因而 ...
曹志友 +5 more
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The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help ...
Changli WANG +7 more
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CEA、CYFRA21-1、NSE、CA125联合检测在肺癌诊断中的价值
Zhongguo shiyan zhenduanxue, 2014 目的评价血清癌胚抗原（CEA）、细胞角蛋白19片段（CYFRA21-1）、神经元特异性烯醇化酶（NSE）、糖类抗原125（CA125）在肺癌诊断中的作用及其联合检测的临床价值。方法选取500例肺癌患者,分为鳞癌、腺癌和小细胞癌3组,采用电化学发光法检测并分析各组间及和50例健康对照组血清CEA,CYFRA21-1,NSE,CA125水平。结果肺癌组的各项肿瘤标志物水平较健康对照组差异具有统计学意义 ...
王文涛, 张国俊
doaj
Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma [PDF]
, 2009 Background and objective GRP78, a member of GRPs, plays a critical role in chemotherapy resistance in some cancers. To investigate the relationship between the expression of GRP78 and resistance to anti-cancer drug VP-16 in vitro in lung adenocarcinoma ...
Li JIANG +3 more
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Zhongguo shiyan zhenduanxue, 2007 目的探讨肺癌肿瘤标记物手术前后变化及其临床意义。方法选经手术治疗25例肺癌患者,监测术前和术后第8天的肿瘤标记物CA125、CA153、CEA和AFP、的变化。结果术后CA125、CA153和CEA水平较术前减低,而AFP手术前后变化不大。结论通过监测肿瘤标记物水平改变可以协助肺癌手术疗效的判断,具有简便、经济的特点,在临床中具有一定的价值。
齐红, 崔焕波, 席妍
doaj
The Expression and Biological Significance of PD-L1 on Lung Cancer Cell Lines [PDF]
, 2009 Background and objective Tumor-associated PD-L1 expression was recently shown to promote T-cell apoptosis and proposed as a potential mechanism of immune evasion by tumors. On the basis of the ability of tumor-associated PD-L1 to mediate activated T-cell
Cheng CHEN +6 more
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Zhongguo shiyan zhenduanxue, 2018 研究发现程序性死亡因子-1(PD-1)、程序性死亡1-配体(PD-L1)在多种肿瘤细胞和肿瘤组织中均有表达,如黑色素瘤、非小细胞肺癌、肾母细胞瘤等,肿瘤组织中过度表达的PD-L1通过与PD-1结合下调抗肿瘤免疫反应[1,2]。目前已有多种免疫药物在临床上应用于多种恶性肿瘤,如pembrolizumab是一种高亲和力的结合PD-1的人源化IgG4-kappa抗体用于治疗晚期黑色素瘤,muvolumab用于治疗鳞状细胞肺癌,并取得美国食品药品管理局(FDA)通过及认证[3 ...
王耿杰 +3 more
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The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]
, 2009 Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
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Zhongguo shiyan zhenduanxue, 2010 目的探讨纤维支气管镜刷检与CT下肺穿刺细胞学对肺癌及其分型的诊断价值。方法对331例患者纤维支气管镜、肺穿涂片,进行瑞-吉氏染色、检验,对结果进行统计、分析,并记录其病理学结果 ,同时对肿瘤标志物CEA、CYFRA21-1、NSE进行检测。结果 331例中肺癌患者140例,细胞学诊断结果敏感性为85.7%,特异性为88.2%,符合率85.7%,其中肺腺癌78.9%,肺鳞癌64.3%,小细胞癌87.1%。肺腺癌肿瘤标志物CEA与对照组、鳞癌组及小细胞癌组比较 ...
赵成艳, 王敏, 何晓琳, 项南
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The Expressions of IL-7 and IL-7R and the Relationship between them with Lymph Node Metastasis and Prognosis in Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective It has been proven that lymph node metastasis was closely related to prognosis of lung cancer. Interleukin-7 (IL-7) and interleukin-7 receptor (IL-7R) could promote lymph node metastasis through vascular endothelial growth factor-
Jian MING +4 more
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