B/C基因型的乙型肝炎病毒在不同ALT状态下对乙型肝炎相关性肾炎的差异性影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】探讨不同ALT状态下B/C基因型的乙型肝炎病毒对乙型肝炎相关性肾小球肾炎的差异性影响。【方法】回顾性分析兰州大学第一医院确诊为乙型肝炎相关性肾小球肾炎的患者558例，所选病人均病历完整，均接受过肾组织病理学检查，化验指标包括：丙氨酸氨基转移酶、肌酐、尿β2微球蛋白、尿N-乙酰-β-D-葡萄糖苷酶、血尿素氮、肾小球滤过率、乙型肝炎病毒载量及基因型。【结果】B型C型基因型的乙肝相关性肾小球肾炎均以弥漫性膜增生性肾病为主（57.9%vs.54.4%），其次为毛细血管内增生性肾小球肾炎（25.3%vs ...
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Predictive value of cystatin C-based estimated glomerular filtration rate combined with thromboelastogram for clinical prognosis of acute-on-chronic liver failure [PDF]
, 2023 Objective To investigate the value of cystatin C-based estimated glomerular filtration rate （eGFR-CysC） combined with thromboelastogram （TEG） to predict clinical prognosis of patients with acute-on-chronic liver failure （ACLF）.
Ba Zhiwei, Zhao Wen, Liu Chuanmiao
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Clinical characteristics and risk factors of acute kidney injury in pediatric diabetic ketoacidosis [PDF]
, 2023 Objective To assess the incidence and clinical characteristics of acute kidney injury （AKI） and explore the associated risk factors in type 1 diabetes mellitus （T1DM） children complicated with diabetic ketoacidosis （DKA）. Methods Clinical data of 76 T1DM
Hu Guosheng, Li Li
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Relationships of Skin AGEs and Serum CN-1 with Microvascular Complications in Type 2 Diabetes Mellitus [PDF]
, 2022 BackgroundHyperglycemia plays a significant role in the development and progression of diabetic complications. While carnosine is a putative scavenger of advanced glycation end products (AGEs) , its availability in tissue is limited by the activity of ...
YANG Guang, XU Xin, ZHANG Yu, XU Juan, JIANG Shujuan, XIA Li, ZHANG Yang, WANG Yikun, LI Zhongsheng, ZHANG Shiqi
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Serum Uric Acid and Long-term Prognosis in Patients with Acute Myocardial Infarction [PDF]
, 2022 BackgroundIt is still controversial whether or not serum uric acid, a key risk for coronary heart disease, is significantly associated with prognosis of acute myocardial infarction (AMI) .
CHEN Qiang, CHEN Yingzhong, CUI Caiyan, JIANG Xinglin, ZHU Feng, LI Siyi, ZHANG Yumei, YE Tao, CAI Lin
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糖尿病肾病（DKD）是指由糖尿病导致的慢性肾脏疾病，受遗传和环境因素及其相互作用的影响，是慢性肾脏病和终末期肾病的主要病因。小檗碱（BBR）是一种天然的异喹啉生物碱。近年来研究发现，BBR具有降血糖、降血脂、抗氧化、抗炎及抗纤维化作用，可以有效改善DKD的肾脏损害，其作用机制可能包括：改善糖脂代谢、减轻氧化应激、减轻炎症反应、改善肾脏纤维化、调控DNA甲基化、改善线粒体功能、调节肠道菌群，改善肠道代谢及清除功能。本文系统性综述了BBR治疗DKD的作用机制的研究现状 ...
曲柄衡, 童晓鹏
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Critical Left Ventricular Ejection Fraction and Its Possible Pathogenesis in STEMI Patients with Supra-normal Ejection Fraction after Primary PCI [PDF]
, 2022 BackgroundLeft ventricular ejection fraction (LVEF) is often used as an assessment indicator for left ventricular systolic function. As adverse events occur in some patients with preserved LVEF, other phenotypes based on LVEF may exist in the population ...
HAO Xiao, ZHAO Mei, LI Shuren
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Influencing Factors of Glycemic Variability in Type 1 Diabetes Patients [PDF]
, 2022 BackgroundThe prevalence of T1DM (type 1 diabetes) is increasing year by year, and its autoimmunity can easily lead to the destruction of pancreaticβcells and insulin deficiency, making blood glucose difficult to reach the target.ObjectiveTo ...
HE Yan, ZHAO Songqing
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Research progress on elderly-onset inflammatory bowel disease [PDF]
, 2023 Inflammatory bowel disease （IBD） is a group of chronic nonspecific intestinal inflammatory diseases with unknown etiology. It has been found that approximately 10%-20% of IBD occurs in old age. At present， the prevalence and quantity of elderly-onset IBD
Lin Jue, Zhi Min, Zhang Min
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Application of evolocumab in patients with coronary heart disease complicated with mild renal insufficiency [PDF]
, 2023 Objective To evaluate the efficacy and safety of evolocumab， a proprotein convertase subtilisin/kexin type 9 （PCSK9） inhibitor， in lowering LDL-C levels in patients with coronary heart disease complicated with mild renal insufficiency.
Zhang Yu, Wu Bin, Feng Jiaxu, Wang Rutao, Yuan Ming
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