Results 11 to 20 of about 1,361 (164)

Effect of sodium‐glucose cotransporter 2 inhibitors on the rate of decline in kidney function: A systematic review and meta‐analysis 钠‐葡萄糖共转运蛋白2抑制剂对肾功能下降速度的影响:系统综述和meta分析

Journal of Diabetes, Volume 15, Issue 1, Page 58-70, January 2023., 2023
Highlights Sodium/glucose cotransporter‐2 inhibitors (SGLT‐2i) showed an important renoprotective effect on sustained administration, regardless of the presence of diabetes, the baseline estimated glomerular filtration rate (eGFR) and different types of SGLT‐2i. There was an acute decline of eGFR in the initial administration (4.02 ml/min/1.73 m2), and
Yanbei Duo, Junxiang Gao, Tao Yuan, Weigang Zhao   +3 more
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Protein pyrrole adducts are associated with elevated glucose indices and clinical features of diabetic diffuse neuropathies 蛋白质吡咯加合物与血糖指数升高和糖尿病弥漫性神经病的临床特征相关

Journal of Diabetes, Volume 14, Issue 10, Page 646-657, October 2022., 2022
Highlights The protein pyrrole adducts in both plasma and urine correlated well with glucose indices, namely fasting blood glucose (FBG) and glycate hemoglobin A1c (HbA1c). Elevated plasma pyrrole adducts was related to positive distal symmetric polyneuropathy (DSPN) symptoms and a high resting heart rate.
Xiao Chen, Zhuyi Jiang, Lianjing Zhang, Wei Liu, Xiaohu Ren, Luling Nie, Desheng Wu, Zhiwei Guo, Weimin Liu, Xifei Yang, Yan Wu, Zhen Liang, Peter Spencer, Jianjun Liu   +13 more
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Kidney disease parameters, metabolic goal achievement, and arterial stiffness risk in Chinese adult people with type 2 diabetes 中国成年2型糖尿病患者的肾脏疾病参数、代谢目标实现情况和动脉硬化风险

Journal of Diabetes, Volume 14, Issue 5, Page 345-355, May 2022., 2022
Highlights Provide key information on the correlation between kidney disease measures and arterial stiffness by evaluating urine albumin‐creatinine ratio and estimated glomerular filtration rate simultaneously in a large sample with type 2 diabetes. Improving management of arterial stiffness, before reaching the chronic kidney disease stage, should ...
Chen Xu, Li Li, Juan Shi, Bangqun Ji, Qidong Zheng, Yufan Wang, Tingyu Ke, Li Li, Dong Zhao, Yuancheng Dai, Fengmei Xu, Ying Peng, Yifei Zhang, Qijuan Dong, Weiqing Wang   +14 more
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Casual C peptide index: Predicting the subsequent need for insulin therapy in outpatients with type 2 diabetes under primary care 随机C肽指数:预测初级保健门诊中2型糖尿病患者对胰岛素治疗的后续需求

Journal of Diabetes, Volume 14, Issue 3, Page 221-227, March 2022., 2022
Highlights Analyses of the factors affecting insulin introduction in the 4‐year period from 2016 and 2020 were conducted. Multivariate logistic regression analysis revealed that C‐CPI contributed the most. The C‐CPI may serve as a convenient useful biomarker for not only the requirement current insulin treatment but also the requirement of insulin ...
Ryota Uehara, Eijiro Yamada, Yasuyo Nakajima, Aya Osaki, Shuichi Okada, Masanobu Yamada   +5 more
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A stratified analysis of a deep learning algorithm in the diagnosis of diabetic retinopathy in a real‐world study 在真实世界研究中深度学习算法在糖尿病视网膜病变诊断中的分层分析

Journal of Diabetes, Volume 14, Issue 2, Page 111-120, February 2022., 2022
Highlights Our deep learning algorithm (DLA)‐based diabetic retinopathy (DR) grading software showed excellent performance in detecting referable DR, especially in patients with type 1 diabetes and diabetic nephropathy who were prone to DR. The DLA showed consistent performance in the detection of referable DR across different subgroups stratified by ...
Na Li, Mingming Ma, Mengyu Lai, Liping Gu, Mei Kang, Zilong Wang, Shengyin Jiao, Kang Dang, Junxiao Deng, Xiaowei Ding, Qin Zhen, Aifang Zhang, Tingting Shen, Zhi Zheng, Yufan Wang, Yongde Peng   +15 more
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A study on the status of normoalbuminuric renal insufficiency among type 2 diabetes mellitus patients: A multicenter study based on a Chinese population 正常蛋白尿的2型糖尿病患者肾功能不全状况的研究:基于中国人群的多中心研究

Journal of Diabetes, Volume 14, Issue 1, Page 15-25, January 2022., 2022
Highlights Approximately 63.6% of diabetes patients with an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 have normal albuminuria. The factors related to normoalbuminuria and eGFR < 60 mL/min/1.73 m2 were male sex, older age, higher triglyceride levels, lower extremity arterial disease, and a longer duration of diabetes. Compared with
Xiaomeng Jia, Li Zang, Ping Pang, Lina Jiang, Jin Du, Weijun Gu, Jianming Ba, Yiming Mu, Zhaohui Lyu   +8 more
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Insulin resistance is associated with urinary albumin‐creatinine ratio in normal weight individuals with hypertension and diabetes: The REACTION study 胰岛素抵抗与尿白蛋白肌酐比值在体重指数正常的高血压合并糖尿病人群中相关:中国REACTION研究

Journal of Diabetes, Volume 12, Issue 5, Page 406-416, May 2020., 2020
Highlights In patients with hypertension and diabetes, early detection and intervention of insulin resistance and related risk factors in patients with normal BMI may reduce the occurrence of urinary microalbumin and delay the progression of CKD. Abstract Background The relationship between albuminuria and insulin resistance (IR) has not been clarified
Shi Gu, Anping Wang, Guang Ning, Linxi Zhang, Yiming Mu   +4 more
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EZSCAN风险评分在肾功能轻度损伤人群中的筛查价值 [PDF]

, 2023
目的自主神经功能障碍是慢性肾脏病（CKD）患者常见严重的并发症，且在CKD早期就会发生。汗腺功能障碍已被视为自主神经功能紊乱的初始组成部分。通过反向离子电渗疗法和计时电流法测量电化学皮肤电导（ESC）来评估汗腺功能，可能会检测出健康体检人群中轻度肾功能不全的患者，以便给予早期干预与治疗，延缓肾功能进一步恶化。方法EZSCAN分数 （0~100） 是基于计时电流分析的专有算法计算得出的。本研究入组了2020年1月至10月浙江大学医学院附属第二医院体检中心健康体检的6 661名受试者，包括肾功能下降 ...
孙婷, 沈国丽, 蔡如意, 邵敏
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Effect of Dapagliflozin on the Risk of New-onset Atrial Fibrillation during Hospitalization for Acute Myocardial Infarction in Patients with Type 2 Diabetes [PDF]

, 2022
BackgroundAtrial fibrillation is a common complication of acute myocardial infarction with an incidence varying from 5% to 20%. New-onset atrial fibrillation developing after acute myocardial fibrillation indicates a significantly increased risk of death
ZHENG Rujie, WANG Yue, JIANG Yaohui, ZHANG Jinying
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Efficacy and safety of lixisenatide as add‐on therapy to basal insulin in older adults with type 2 diabetes in the GetGoal‐O Study GetGoal‐O研究中老年2型糖尿病患者使用基础胰岛素加利西那肽治疗的有效性与安全性

Journal of Diabetes, Volume 11, Issue 12, Page 971-981, December 2019., 2019
Highlights This post hoc analysis of the GetGoal‐O trial suggests that add‐on therapy with lixisenatide in non‐frail patients aged ≥70 years with type 2 diabetes uncontrolled on basal insulin is safe and well tolerated and should be considered in this patient population as an alternative to rapid‐acting insulin.
George E. Dailey, Terry A. Dex, Michelle Roberts, Minzhi Liu, Graydon S. Meneilly   +4 more
wiley   +1 more source