Results 21 to 30 of about 7,900 (173)
Highlights This consensus document identifies challenging areas and strategic recommendations for the effective management of cardiorenal complications in type 2 diabetes mellitus in the Middle East and North Africa and Africa. There is a need for optimum glycemic control, early identification of cardiorenal complications, along with risk management ...
Alper Sonmez +12 more
wiley +1 more source
Highlights Provide key information on the correlation between kidney disease measures and arterial stiffness by evaluating urine albumin‐creatinine ratio and estimated glomerular filtration rate simultaneously in a large sample with type 2 diabetes. Improving management of arterial stiffness, before reaching the chronic kidney disease stage, should ...
Chen Xu +14 more
wiley +1 more source
Highlights C3c deposition in the kidney was associated with worse renal outcomes and was an independent predictor for ESRD in DKD patients with T2DM. C3c deposition in the kidney might be a novel biomarker indicating DKD progression in T2DM. Abstract Background Although extensive efforts have been paid to identify reliable predictors for renal outcomes
Meng‐Rui Li +6 more
wiley +1 more source
Highlights The prognostic value of combining tubular basement membrane (TBM) and glomerular basement membrane (GBM) in diabetic nephropathy (DN) was lacking. TBM thickness was strongly correlated with GBM thickness, baseline estimated glomerular filtration rate, and proteinuria. The degree of TBM thickness provided additional value to GBM thickness for
Lijun Zhao +13 more
wiley +1 more source
Highlights Admission serum or point‐of‐care glucose is a greater predictor of mortality than glycosylated hemoglobin in persons with type 2 diabetes and coronavirus disease 2019 (COVID‐19). Those with diabetes and COVID‐19 who were intubated had a higher morality than those who were not intubated.
Alyson K. Myers +5 more
wiley +1 more source
Chinese Medical Entity Recognition Model Based on Character and Word Vector Fusion
The medical information carried in electronic medical records has high clinical research value, and medical named entity recognition is the key to extracting valuable information from large‐scale medical texts. At present, most of the studies on Chinese medical named entity recognition are based on character vector model or word vector model.
Qinghui Zhang +5 more
wiley +1 more source
TGF-β1/SMAD在糖尿病肾病中的作用机制与研究进展 [PDF]
Diabetic nephropathy (DN) is a common complication of diabetes and a leading cause of end-stage renal disease. Transforming growth factor-β1 (TGF-β1)/SMAD signaling activation plays an important role in the onset and progression of DN.
Chen, Haiyong +4 more
core +1 more source
高血压可以导致全身多个器官及系统的病变,其中肾脏是其损害的重要靶器官[1-2]。原发性高血压导致的肾脏损害主要体现为肾脏血管病变,称为良性肾小动脉硬化,晚期可见肾小球的萎缩及硬化,并最终导致肾功能完全丧失。而在肾脏功能受损的过程中,由于肾脏对水钠排泄障碍、血管内皮损伤因子增加、肾素-血管紧张素-醛固酮系统的激活等也可导致血压进一步增高。63%-90%的恶性高血压患者存在不同程度的肾脏结构和功能损害[3],且可快速发展至终末期肾脏病。
王淑平 +3 more
doaj
Highlights In patients with hypertension and diabetes, early detection and intervention of insulin resistance and related risk factors in patients with normal BMI may reduce the occurrence of urinary microalbumin and delay the progression of CKD. Abstract Background The relationship between albuminuria and insulin resistance (IR) has not been clarified
Shi Gu +4 more
wiley +1 more source
肾脏肿瘤或者肾动脉瘤破裂、钝性或穿透性肾脏损伤均可导致致命性肾脏出血。临床诊疗操作过程中,肾脏出血也时有发生,例如肾脏活检(PKB)、经皮肾造瘘、肾脏部分切除术(PN)、经皮肾镜取石术(PCNL)、肾动脉血管腔内成形术(PTRA)等[1-4]。肾脏出血的自发止血率仅为11%[5],保守处理疗效欠佳。1973年首次报道了肾动脉栓塞(RAE)对PKB相关动静脉瘘(AVF)进行干预[6]。为进一步探讨与RAE相关的临床问题,本文进行了病例回顾分析,报道如下。1材料与方法1 ...
张海峰 +6 more
doaj

