Zhongguo shiyan zhenduanxue, 2018 目的测定vinculin在大肠癌及肾癌组织中的表达情况,探究其在大肠癌及肾癌发生发展中的意义。方法用二维液相色谱-质谱联用技术对20例DukesB期大肠癌患者的癌组织及癌旁组织、18例透明细胞肾癌患者的癌组织及癌旁组织中vinculin表达水平进行检测,并通过免疫印迹实验进一步验证。结果 vinculin在大肠癌组织中的表达水平低于其癌旁组织,相反,在肾癌组织中表达较其癌旁组织高。结论 vinculin在大肠癌及肾癌的发生发展中起一定作用。
郑岩 +5 more
doaj
MAPK4 Accelerates Progression of Cervical Squamous Cell Carcinoma by Positively Regulating SLC3A2 Expression [PDF]
ObjectiveTo explore the role of MAPK4 in cervical squamous cell carcinoma (CSCC) for the identification of candidate prognostic prediction biomarkers and molecular therapeutic targets.
Jing YU +4 more
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Zhongguo shiyan zhenduanxue, 2019 VHL综合征是一种可引起多种良恶性肿瘤的遗传性疾病,每36000人中就有一人罹患该病。该病是由VHL基因无法正常表达引起的。VHL基因是一种抑癌基因,定位于染色体3p25-26。本文阐述了关于VHL综合征相关肾透明细胞癌的诊断治疗方法。1 VHL综合征1.1 VHL综合征是一种由VHL抑癌基因的突变引起的累及多器官的显性遗传病,影响包括中枢神经系统、肾脏、胰腺、肾上腺及生殖系统 ...
玄磊 +4 more
doaj
Expression and clinical significance of geranylgeranyl diphosphate synthase1 (GGPS1) in lung squamous cell carcinoma [PDF]
Objective·To investigate the expression and clinical significance of geranylgeranyl diphosphate synthase1 (GGPS1) in lung squamous cell carcinoma (LUSC) by bioinformatics and immunohistochemistry.Methods·Firstly, the transcriptome data of LUSC tissues ...
JIA Xiangdong +7 more
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Recent Advances and Strategies in the Development of Therapeutic Radiopharmaceuticals [PDF]
Therapeutic radiopharmaceuticals can be employed in the treatment of various tumor diseases，and their global market share is likely to witness an explosive growth in the recent decade.
Hao CHEN +8 more
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Zhongguo shiyan zhenduanxue, 2010 目的探讨卵泡抑素在卵巢癌患者血清中的水平变化及其临床意义。方法采用ELISA法检测肿瘤患者及健康对照者血清FS水平;免疫组织化学染色观察卵巢癌组织FS表达情况。结果卵巢癌患者血清FS水平明显高于健康对照组,统计学比较差异显著,P乳腺癌（40%）>肺癌（30%）>胃癌（20%）>肾癌（0%）。免疫组织化学染色显示,卵巢癌组织表达FS与肿瘤类型有关,染色强度依次为粘液性癌>子宫内膜样癌>透明细胞癌>鳞癌>浆液性癌。结论卵巢癌患者血清FS水平升高,其诊断阳性率与卵巢肿瘤类型有关 ...
陈芳芳 +5 more
doaj
Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions [PDF]
Background and purpose: Abnormal DNA methylation is closely associated with the onset and progression of tumors. This study aimed to investigate the expression of intermediate filament family orphan 1 (IFFO1), a methylation-driven gene (MDG) in ...
XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou
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[Mechanism of nuclear protein 1 in the resistance to axitinib in clear cell renal cell carcinoma]. [PDF]
Beijing Da Xue Xue Bao Yi Xue Ban, 2023 Liu YC +7 more
europepmc +1 more source
[Correlation between metabolic syndrome and prognosis of patients with clear cell renal cell carcinoma]. [PDF]
Beijing Da Xue Xue Bao Yi Xue Ban, 2022 Zuo MN, DU YQ, Yu LP, Dai X, Xu T.
europepmc +1 more source
China Anti-Cancer Association guideline for diagnosis and treatment of neuroendocrine neoplasms (2025 edition) [PDF]
Neuroendocrine neoplasms (NENs) are a rare group of tumors that originated from peptidergic neurons and neuroendocrine cells, which has neuroendocrine differentiation characteristics and expresses neuroendocrine markers.
Society of Neuroendocrine Neoplasm of China Anti-Cancer Association
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