[Anti-inflammatory effects of cell membrane vesicle-mediated delivery of small interfering RNA targeting tumor necrosis factor-α on dental pulp stem cells]. [PDF]
Gao R +6 more
europepmc +1 more source
[Exploring the research on the molecular mechanisms of autoimmune liver diseases]. [PDF]
Liu YQ, Jiang XW, Li Y, Liu XL.
europepmc +1 more source
【目的】 探讨氧控制性再灌注(OCR)对体外循环肺缺血再灌注(I/R)早期损伤的作用65377; 【方法】 14只健康犬随机分为对照组(I/R,n = 7)和实验组(OCR, n = 7)65377;对照组全程FiO2 80%;实验组在主动脉开放即刻调整FiO2至40%,随后每5 min依次上调10%,最后达80%,其余时段均维持FiO2 80%65377;检测动脉血气,观察两组犬在麻醉后65380;主动脉开放前65380;开放后565380;1065380;1565380;2065380;25 ...
doaj
[Progress in the Immune Mechanism of Microwave Ablation Therapy for Lung Cancer]. [PDF]
Yang Z, Chen X, Jiang J.
europepmc +1 more source
[Research Progress on the Regulatory Mechanism of Respiratory Microbiota in the Comorbidity of Chronic Obstructive Pulmonary Disease and Lung Cancer]. [PDF]
Zhang Y, Zhang T, Wang H.
europepmc +1 more source
Receptor activator of nuclear factor-κB ligand and tumor necrosis factor-α promotes osteoclast differentiation through the exosomes of inflammatory periodontal ligament stem cells. [PDF]
Dai Z, Zheng W, Li S.
europepmc +1 more source
单羧酸转运蛋白4调控口腔鳞状细胞癌肿瘤相关巨噬细胞极化的机制研究
目的探讨靶向抑制单羧酸转运蛋白4(MCT4)对肿瘤相关巨噬细胞(TAMs)极化的影响及机制。方法采用佛波醇-12-十四酸酯-13-乙酸酯(PMA)诱导人单核细胞白血病细胞(THP-1)为巨噬细胞后,以MCT4特异性抑制剂VB124或二甲基亚砜(DMSO)预处理,再与人口腔鳞状细胞癌(OSCC)细胞株CAL27进行Transwell共培养诱导TAMs。蛋白免疫印迹(Western blot)法检测巨噬细胞和TAMs中MCT4的蛋白表达;流式细胞术、免疫荧光染色以及Western ...
刘璐 +4 more
doaj
[A Case Report of Successful Control of Refractory Tumor Fever in Lung Adenocarcinoma with Interleukin-6 Antibody Tocilizumab]. [PDF]
Li Y, Li C, Li B.
europepmc +1 more source
[Research advances on the targeted programmed cell death regulatory network for treatment of refractory diabetic wounds]. [PDF]
Zhang ZH, He WF.
europepmc +1 more source
【目的】 探讨右旋美托咪啶在脑缺血再灌注损伤中的保护作用和相关机制。【方法】 42只雄性SD大鼠随机分为3组,每组14只:右旋美托咪啶组(Dex)采用右旋美托咪啶5 μg·kg-1·h-1恒速输注2 h;拮抗剂组(Dex+Yoh)于开启注射泵前10 min经尾静脉输注拮抗剂育亨宾1 mg/kg,余用法同上组;对照组(Con)以同等速度输注生理盐水2h。所有大鼠行大脑中动脉栓塞术,缺血90 min后再灌注。观察术后24 h神经功能评分、脑梗死体积、水肿指数以及脑组织白介素(IL)-1β、肿瘤坏死因子 ...
doaj

