Results 11 to 20 of about 8,344 (191)
Zhongguo shiyan zhenduanxue, 2017 目的确定维持性血液透析透患者癌胚抗原（CEA）、鳞状细胞癌抗原（SCC）、角蛋白19片段（Cyfra21-1）,神经元特异性烯醇化酶（NSE）等肺癌肿瘤标志物的特殊人群参考值范围。方法选择我院2011年至2014年血液净化科维持性血液透析6个月以上的终末期肾病患者共320例,其中男158例,女162例,健康查体者372例,男189例,女183例,采用电化学发光法检测角蛋白19片段（Cyfra21-1）,神经元特异性烯醇化酶（NSE）,采用化学发光法检测癌胚抗原（CEA）、鳞状细胞癌抗原（SCC ...
焦妍, 赵洪刚, 张遵城
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Zhongguo shiyan zhenduanxue, 2015 肿瘤标志物（tumor marker,TM）是指在恶性肿瘤发生和生长过程中,由肿瘤细胞的基因表达而合成分泌的或因肿瘤细胞反应而异常产生和（或）升高的,提示肿瘤存在和生长的一类物质[1]。近年来,随着分子生物学技术的迅猛发展,检测手段不断提高,已有多种检测技术,现针对肿瘤标记物相关分子生物学检测技术及其发展作一综述。1分子诊断技术1 ...
李时孟, 潘宝香, 刘春迎, 谢风
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Zhongguo shiyan zhenduanxue, 2017 目的探讨痰液细胞原血红素联合肿瘤标志物检测对非小细胞肺癌诊断的临床意义。方法选择我院收治的70例非小细胞肺癌患者（NSCLC组）、85例肺良性疾病患者（肺良性疾病组）、50例体检健康者（健康对照组）作为研究对象,所有入组对象入院后均进行痰液细胞原血红素检查、癌胚抗原（CEA）、糖蛋白抗原19-9（CA19-9）、神经元特异性烯醇化酶（NSE）检查,分析不同组别痰液细胞原血红素、肿瘤标志物水平差异,分析痰液细胞原血红素、肿瘤标志物及联合检测的阳性率及诊断价值。结果 NSCLC组、肺良性疾病组 ...
刘建博
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Zhongguo shiyan zhenduanxue, 2016 肺癌其初期不易被检测到,后期病情发展迅速,不易控制,因此越早发现、及时准确诊断及分期,对其治疗及预后意义重大。近年来,血清肿瘤标志物检测在全身肿瘤病灶诊断中越来越广泛的被应用。多种血清肿瘤标志物联合检测作为应用于肺部疾病的生物学诊断,可以提高其诊断准确率[1,2]。1资料与方法1.1临床资料对2011年11月至2013年9月在我院就诊的肺部原发疾病的患者,进行癌胚抗原（CEA ...
刘春海 +5 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 探讨胰腺类癌的临床和病理学特点65377;【方法】 对1997年1月1日至2007年12月31日期间手术治疗的8例胰腺类癌临床病理资料(如肿瘤标志物65380;病理免疫组织化学染色65380;伴发其他肿瘤65380;误诊率65380;肿瘤转移率65380;住院死亡率65380;手术根治率等)进行回顾性分析,并结合国内外文献探讨胰腺类癌的临床和病理学特点65377; 【结果】 肿瘤标志物CEA65380;CA19965380;CA12565380;CA72-4在胰腺类癌的表达阳性率分别为0 ...
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Canine melanocytes: Immunohistochemical expression of melanocytic markers in different somatic areas
Veterinary Dermatology, Volume 34, Issue 4, Page 284-297, August 2023., 2023 Background – Melanoblasts originate in the neural crest from where they migrate to peripheral tissues and differentiate into melanocytes. Alteration during melanocyte development and life can cause different diseases, ranging from pigmentary disorders and decreased visual and auditory functions, to tumours such as melanoma.
Ilaria Porcellato +5 more
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Journal of Diabetes, Volume 15, Issue 4, Page 325-331, April 2023., 2023 Highlights Leukocyte telomere length was independently associated with the risk of cardiovascular mortality. Leukocyte telomere length was not associated with the risk of all‐cause mortality in patients with diabetes. Telomere length may be a predictor of cardiovascular mortality in diabetes.
Ziwei Chen +6 more
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Effect of type 2 diabetes on A disintegrin and metalloprotease 10 2型糖尿病对解整合素金属蛋白酶10表达的影响
Journal of Diabetes, Volume 14, Issue 6, Page 394-400, June 2022., 2022 Highlights a disintegrin and metalloprotease 10 (ADAM10), a sheddase responsible for the cleavage of a variety of cell surface molecules, has been implicated in the pathogenesis of Alzheimer disease, atherosclerosis, and inflammatory and neoplastic disorders, and systemic ADAM10 concentration may potentially be used as a prognostic biomarker. Our study
Sum Lam +3 more
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Serum concentrations of IL‐31 in dogs with nonpruritic mast cell tumours or lymphoma
Veterinary Dermatology, Volume 31, Issue 6, Page 466-e124, December 2020., 2020 Background The aim of this study was to compare serum interleukin (IL)‐31 concentrations in dogs with lymphoma and mast cell tumours (MCT) without pruritus to those of healthy dogs. Hypothesis/Objectives To determine if IL‐31 plays a role in tumour pathogenesis and if IL‐31 could be a biological marker for disease progression.
Nataliia Ignatenko +8 more
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肿瘤标志物SCC-Ag、Cyf21-1、CEA、ProGRP、及NSE联合检测在肺癌诊断中的应用
Zhongguo shiyan zhenduanxue, 2019 目的通过体外分析检测血清中鳞状细胞癌抗原(SCC-Ag)、细胞角蛋白19片段抗原(Cyf21-1)、癌胚抗原(CEA)、胃泌素释放肽前体(ProGRP)及神经元特异性烯醇化酶(NSE)5种肿瘤标志物在健康体检者、肺良性疾病和肺癌人群中含量的差异,分析五种肿瘤标志物联合检测的可行性。方法回顾性分析2015年1月到2018年7月我院相关科室收治明确诊断肺癌患者90例,肺良性病变患者90例,体检中心健康体检者90例。通过收集三组数据进行比较分析,对比5种肿瘤标志物独立诊断与联合诊断肺癌的敏感性和特异性 ...
董芸, 袁峥玺, 姚原
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