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CEA vaccines

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Carcinoembryonic antigen (CEA) is a glycosylated cell surface oncofetal protein involved in adhesion, proliferation, and migration that is highly upregulated in multiple carcinomas and has long been a promising target for cancer vaccination. This review summarizes the progress to date in the development of CEA vaccines, examining both pre-clinical and ...
Anchit Bhagat   +3 more
openaire   +3 more sources

Colorectal carcinoma evidence for circulating CEA-anti-CEA complexes [PDF]

open access: yesCancer, 2006
Significant increments in measurable plasma CEA were effected by 2.5 M MgCl2 elution from putative circulating CEA-anti-CEA complexes in 11 of 15 patients with disseminated colorectal cancer and in five of ten patients with a high probability of having subclinical disease (Dukes'C category). Following 2.5 M MgCl2 elution, IgG from a patient with a high
G M, Mavligit, S, Stuckey
openaire   +2 more sources

CEA-based vaccines

open access: yesExpert Review of Vaccines, 2002
Carcinoembryonic antigen (CEA), the first tumor-associated antigen to be described, was cloned in 1987 and is expressed on nearly 50% of all human tumors. The identification of T-cell specific epitopes within the coding region of the CEA protein has led to the development of various vaccine strategies that target CEA and CEA-expressing tumors.
Emina H, Huang, Howard L, Kaufman
openaire   +2 more sources

Tumor Marker Index Based on CEA and CA19-9 as a Prognostic Biomarker in Resectable Colon Cancer. [PDF]

open access: yesCancer Diagn Progn
Kosuge T   +9 more
europepmc   +1 more source

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