Results 81 to 90 of about 9,092 (156)

Construction and Verification of A Nomogram Model for Predicting Invasive Risk of Ground Glass Nodules [PDF]

open access: yes
Objective To investigate the importance of a nomogram model based on biomarkers and CT signs in the prediction of the invasive risk of ground glass nodules.
JIN Bingji   +3 more
core   +1 more source

前列腺癌的诊断研究进展

open access: yesZhongguo shiyan zhenduanxue, 2005
论述前列腺肿瘤诊断及鉴别诊断中应用的标志物,为前列腺癌的早期诊断积累经验,同时认为基因芯片技术是寻找前列腺癌更特异标志物的有效方法。
刘仲祥, 杨华
doaj  

结直肠肿瘤组织中HIST1H3B的表达变化及意义

open access: yesZhongguo shiyan zhenduanxue, 2020
结直肠癌为世界最常见的恶性肿瘤之一。内镜、粪便检查、肿瘤标志物等都是有效的结直肠癌筛查手段[1,2]。本次实验通过探究HIST1H3B在结直肠癌的表达量及临床意义,为结直肠癌诊断探究潜在的新型生物标志物。1材料与方法1.1研究对象本实验所选取的样本来源于吉林大学中日联谊医院2017年5月至2018年1月经消化外科手术所得共计34例,其采集标本的标准为:经病理科检验证实为结直肠癌Dukes B期的腺癌,
李凯迪   +5 more
doaj  

Mirk/Dyrk1b在上皮性卵巢癌组织中的表达及意义 [PDF]

open access: yes, 2011
目的:探讨Mirk/Dryk1b(Minibrain-related kinase/Dual specificity tyrosine-phosphorylation-regulated kinase1B)在卵巢组织中的表达及其临床意义。方法:利用免疫组化检测Mirk/Dyrk1b在30例上皮性卵巢癌、20例上皮性卵巢囊腺瘤、10例正常卵巢组织中的表达。结果:Dyrk1b在上皮性卵巢癌中的表达明显高于上皮性卵巢囊腺瘤及正常卵巢组织(P0.05)。结论:Dyrk1b在上皮性卵巢癌中高表达 ...
廖洪锋   +7 more
core  

循环肿瘤细胞在肿瘤诊断中的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2019
恶性肿瘤因其较高的发病率和死亡率,成为严重威胁人类健康的主要疾病之一。液体活检能够应用于肿瘤的早期诊断、预后监测、复发转移、个体化治疗和疗效评估等方面[1]。液体活检用于检测的生物标志物有:循环肿瘤DNA(circulating tumor DNA,ctDNA),循环肿瘤细胞 ...
杨梅   +5 more
doaj  

Expression and Clinical Significance of mTOR and PTEN in Non-small Cell Lung Cancer [PDF]

open access: yes, 2010
Background and objective It has been proved that mTOR was an important signal transduction molecular and protein kinase regulating cell growth and proliferation, and mTOR could activate the downstream protein effector. PTEN could negatively regulate mTOR
Liang WANG   +5 more
core  

Effect of intraperitoneal hyperthermic perfusion chemotherapy after laparoscopic surgery for colorectal cancer and the changes in the HMGB1 and RAGE level [PDF]

open access: yes
Objective To investigate the efficacy of hyperthermic intraperitoneal chemotherapy(HIPEC) after laparoscopic surgery for colorectal cancer and the changes in the high mobility group box 1(HMGB1)and receptor for advanced glycation end products(RAGE ...
LIANG Qizheng,FAN Yue,FU Yang,LI Guodong
core   +2 more sources

肝癌患者血浆游离DNA检测的意义

open access: yesZhongguo shiyan zhenduanxue, 2012
近年,血浆游离DNA(cell-free DNA,cfDNA)受到越来越多的关注。新近一期《Science》杂志专门刊登编辑文章强调cfDNA可能是血液中的潜在的生物标志物[1]。cfDNA的检测就如"液态的组织活检(liquid biopsy)",有可能代替现在的肿瘤活组织检查[2]。研究表明cfDNA浓度在肿瘤患者中升高[3],且随肿瘤大小、部位以及严重程度而不同[4]。
彭兰, 陈孝进, 王克仕, 黄维红
doaj  

Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer [PDF]

open access: yes, 2010
Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Cheng ZHAO   +4 more
core  

Clinical value analysis of simple resection of pancreatic solid pseudopapillary tumor [PDF]

open access: yes
Objective To explore the clinical application value of simple resection in the treatment of pancreatic solid pseudopapillary tumor(SPT). Methods Retrospective analysis of clinical and follow-up data of pancreatic SPT patients who underwent simple ...
GUO Yujie, TANG Ying, GU Jichun, YANG Feng, LIU Huaye, JIN Chen, FU Deliang, Li Ji
core   +1 more source

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