Results 111 to 120 of about 38,945 (161)
, 2017 目的检测地榆皂苷II对多种肿瘤细胞的体外增殖抑制作用,研究地榆皂苷II诱导肿瘤细胞凋亡的分子机制。方法采用SRB法检测地榆皂苷II对肿瘤细胞的体外增殖抑制,通过Western blot来研究地榆皂苷II对三大凋亡通路的影响。结果地榆皂苷Ⅱ可上调MDA-MB-231细胞中活性氧的水平,上调CHOP的表达,激活内质网应激途径;下调Bcl-2的表达,上调Bax的表达,激活线粒体凋亡途径;上调DR4、DR5的表达,激活TRAIL外源凋亡通路。结论地榆皂苷II通过激活三大细胞凋亡通路来抑制肿瘤细胞的增殖 ...
张强 +6 more
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[Clinical Progress and Prospects of mRNA Tumor Drugs]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanChen J +5 more
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[Research Advances on the Immune Evasion Mechanisms of Disseminated Tumor Cells and Their Roles in Cancer Metastasis]. [PDF]
Zhongguo Fei Ai Za ZhiQue Z, Luo B, Tian J.
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Programmable DNAzyme nanocatalysts for tumor immunometabolic modulation. [PDF]
J Zhejiang Univ Sci BLuo R +7 more
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[Liquid Biopsy Revolutionizes the Precise Management of Tumors Across the Entire Course: Current Situation and Future Prospects]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZeng J, Zhang J.
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Inflammation and tumor microenvironment. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Niu T, Zhou F.
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, 2016 本发明公开了ELL(C595A)在促进肿瘤细胞迁移中的应用，本发明提供了ELL(C595A)蛋白在如下1)-6)至少一种中的应用：1)制备促进肿瘤转移产品；2)制备促进肿瘤细胞迁移产品；3)制备提高肿瘤细胞侵袭能力产品；4)制备提高与肿瘤转移相关的基因表达产品；5)制备用于筛选治疗肿瘤转移的动物模型；6)制备用于研究肿瘤转移机制的动物模型；本发明发现ELL突变体ELL(C595A)蛋白，促进肿瘤转移，提高肿瘤细胞侵袭能力；可制备用于筛选治疗肿瘤转移药物的动物模型；可制备用于研究肿瘤转移机制的动物模型。
陈瑜, 肖武汉
core
[Research progress on protein lactylation modification in malignant tumors]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanDong H, Chen H, Zhang C.
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[Gut microbiota involved in cancer invasion and metastasis]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanHuang S, Yang Q, Zhou W.
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[Clinical efficacy of thinned free flaps in reconstructing the wounds following excision of malignant extremity tumors]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za ZhiLi B +7 more
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